Search Results - "Reisinger, Sonali N."
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Maternal immune activation transgenerationally modulates maternal care and offspring depression-like behavior
Published in Brain, behavior, and immunity (01-07-2017)“…Highlights • Maternal immune activation (MIA) during pregnancy impacts maternal care behavior. • Modulation of maternal care behavior in female offspring after…”
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STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior
Published in Scientific reports (11-03-2015)“…Experimental evidence suggests a role for the immune system in the pathophysiology of depression. A specific involvement of the proinflammatory cytokine…”
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Effect of Chronic Corticosterone Treatment on Depression-Like Behavior and Sociability in Female and Male C57BL/6N Mice
Published in Cells (Basel, Switzerland) (01-09-2019)“…Depression is a very common psychiatric disorder affecting approximately 300 million people worldwide with the prevalence being twice as high in women as in…”
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Life‐long impairment of glucose homeostasis upon prenatal exposure to psychostimulants
Published in The EMBO journal (02-01-2020)“…Maternal drug abuse during pregnancy is a rapidly escalating societal problem. Psychostimulants, including amphetamine, cocaine, and methamphetamine, are…”
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Maternal immune activation epigenetically regulates hippocampal serotonin transporter levels
Published in Neurobiology of stress (01-10-2016)“…Major depressive disorder (MDD) is one of the most debilitating psychiatric diseases, affecting a large percentage of the population worldwide. Currently, the…”
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Mimicking bacterial infection in male mice changes sperm small RNA profiles and multigenerationally alters offspring behavior and physiology
Published in Brain, behavior, and immunity (01-07-2024)“…•Administration of bacterial mimic (LPS) to male mice induced transgenerational impacts on offspring phenotypes.•F1 offspring and F2 grand-offspring of LPS…”
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Paternal immune activation by Poly I:C modulates sperm noncoding RNA profiles and causes transgenerational changes in offspring behavior
Published in Brain, behavior, and immunity (01-01-2024)“…Paternal pre-conceptual environmental experiences, such as stress and diet, can affect offspring brain and behavioral phenotypes via epigenetic modifications…”
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Depletion of the paternal gut microbiome alters sperm small RNAs and impacts offspring physiology and behavior in mice
Published in Brain, behavior, and immunity (01-01-2025)“…•Administration of antibiotics to male mice induced intergenerational impacts on offspring physiology and behavior.•F1 offspring of gut microbiome-depleted…”
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PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model
Published in Translational psychiatry (11-02-2019)“…The serotonin transporter (SERT, Slc6a4) plays an important role in the regulation of serotonergic neurotransmission and its aberrant expression has been…”
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STAT3 in the dorsal raphe gates behavioural reactivity and regulates gene networks associated with psychopathology
Published in Molecular psychiatry (01-07-2021)“…The signal transducer and activator of transcription 3 (STAT3) signalling pathway is activated through phosphorylation by Janus kinases in response to a…”
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Lmo3 deficiency in the mouse is associated with alterations in mood-related behaviors and a depression-biased amygdala transcriptome
Published in Psychoneuroendocrinology (01-01-2020)“…•Lmo3 deficiency is associated with alterations in emotional behavior.•Absence of Lmo3 impairs amygdala LTP.•Amygdala transcriptome is selectively altered in…”
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Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour
Published in Scientific reports (15-07-2015)Get full text
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Correction: Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour
Published in Scientific reports (15-07-2015)“…Experimental evidence suggests a role for the immune system in the pathophysiology of depression. A specific involvement of the proinflammatory cytokine…”
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