Search Results - "Reiser, Christian O.A."

Efficient Intracellular Delivery of a Protein and a Low Molecular Weight Substance via Recombinant Polyomavirus-like Particles by Abbing, Andrea, Blaschke, Ulrich K., Grein, Swen, Kretschmar, Michael, Stark, Christoph M.B., Thies, Michael J.W., Walter, Jürgen, Weigand, Martina, Woith, Diemuth C., Hess, Jürgen, Reiser, Christian O.A.

“…Efficient encapsulation of foreign molecules like proteins and low molecular weight drugs into polyoma virus-like particles (capsoids) was achieved by the…”
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Crystal structure of active elongation factor Tu reveals major domain rearrangements by Berchtold, Harald, Reshetnikova, Ludmila, Reiser, Christian O. A, Schirmer, Norbert K, Sprinzl, Mathias, Hilgenfeld, Rolf

“…The crystal structure of intact elongation factor Tu (EF-Tu) from Thermus thermophilus has been determined and refined at an effective resolution of 1.7 A,…”
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The platelet-derived-growth-factor receptor, not the epidermal-growth-factor receptor, is used by lysophosphatidic acid to activate p42/44 mitogen-activated protein kinase and to induce prostaglandin G/H synthase-2 in mesangial cells by Goppelt-Struebe, M, Fickel, S, Reiser, C O

“…In renal mesangial cells, activation of protein tyrosine kinase receptors may increase the activity of mitogen-activated protein (MAP) kinases and subsequently…”
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Beneficial therapeutic effects with different particulate structures of murine polyomavirus VP1-coat protein carrying self or non-self CD8 T cell epitopes against murine melanoma by Brinkman, Marc, Walter, Juergen, Grein, Swen, Thies, Michael J W, Schulz, Torsten W, Herrmann, Martin, Reiser, Christian O A, Hess, Juergen

“…Polyomavirus-like-particles (PLPs) are empty, non-replicative, non-infectious particles that represent a potent antigen-delivery system against malignant…”
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Lysophosphatidic acid-mediated signal-transduction pathways involved in the induction of the early-response genes prostaglandin G/H synthase-2 and Egr-1: a critical role for the mitogen-activated protein kinase p38 and for Rho proteins by Reiser, C O, Lanz, T, Hofmann, F, Hofer, G, Rupprecht, H D, Goppelt-Struebe, M

“…During inflammatory processes of the kidney, lesions of the glomerulus lead to aggregation of thrombocytes and infiltration of macrophages, which can release…”
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Development of a vaccine marker technology: Display of B cell epitopes on the surface of recombinant polyomavirus-like pentamers and capsoids induces peptide-specific antibodies in piglets after vaccination by Neugebauer, Markus, Walders, Birgit, Brinkman, Marc, Ruehland, Claus, Schumacher, Thomas, Bertling, Wolf M., Geuther, Eugen, Reiser, Christian O. A., Reichel, Christoph, Strich, Sandra, Hess, Juergen

“…Highly immunogenic capsomers (pentamers) and virus‐like particles (VLPs) were generated through insertion of foreign B cell epitopes into the surface‐exposed…”
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Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells by BICKERT, Thomas, WOHLLEBEN, Gisela, BRINKMAN, Marc, TRUJILLO-VARGAS, Claudia M, RUEHLAND, Claus, REISER, Christian O. A, HESS, Juergen, ERB, Klaus J

“…We analysed the effects of murine polyomavirus-like particles (PLPs) on bone marrow-derived dendritic cells (BMDCs) and T cells in vitro. BMDCs activated with…”
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Independent regulation of cyclo-oxygenase 2 expression by p42/44 mitogen-activated protein kinases and Ca2+/calmodulin-dependent kinase by Goppelt-Struebe, M, Hahn, A, Stroebel, M, Reiser, C O

“…5-Hydroxytryptamine (5-HT, 'serotonin') is a potent inducer of the early response gene cyclo-oxygenase 2 (Cox-2; prostaglandin G/H synthase) in mesangial…”
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ImmunoTrack®: The novel antibody-based technology for tracing in animal health by Ruehland, Claus, Reichel, Christoph, Neugebauer, Markus, Strich, Sandra, Bertling, Wolf M., Reiser, Christian O. A., Hess, Juergen

“…This paper describes a novel antibody‐based livestock movement control tool and method of meat allocation, both in livestock husbandry as well as during the…”
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Advanced antigen delivery of murine survivin: chimeric virus-like particles in cancer vaccine research by Schumacher, Thomas, Ruehland, Claus, Schultheiss, Christine, Brinkman, Marc, Roedel, Franz, Reiser, Christian O A, Hess, Juergen, Reichel, Christoph

“…Success in cancer immunotherapy depends on the identification and efficient targeting of specific tumor-associated antigens. Two pivotal strategies to prime…”
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Modulation of Prostaglandin G/H Synthase Expression in Mesangial Cells Transfected by pp60c-srcProto-oncogene by Reiser, Christian O.A., Marx, Martin, Hoppe, Jürgen, Goppelt-Struebe, Margarete

“…The role of the protein tyrosine kinase pp60c-srcin the expression of prostaglandin G/H synthase (PGHS), the key enzyme of prostaglandin synthesis, was…”
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Nucleotide binding and GTP hydrolysis by elongation factor Tu from Thermus thermophilus as monitored by proton NMR by Limmer, Stefan, Reiser, Christian O. A, Schirmer, Norbert K, Grillenbeck, Norbert W, Sprinzl, Mathias

“…Proton NMR experiments of the GTP/GDP-binding protein EF-Tu from the extremely thermophilic bacterium Thermus thermophilus HB8 in H2O have been performed…”
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Purification and characterization of a NADH oxidase from the thermophile Thermus thermophilus HB8 by PARK, Ho‐Jin, REISER, Christian O. A., KONDRUWEIT, Simone, ERDMANN, Helmut, SCHMID, Rolf D., SPRINZL, Mathias

“…A NADH oxidase has been purified from the extreme thermophile Thermus thermophilus HB8 by several chromatographic steps. The purified enzyme was essentially…”
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Modulation of phospholipase D stimulation in c-src transfected mesangial cells by Reiser, Christian O.A., Goppelt-Struebe, Margarete

“…Stimulation of rat mesangial cells with platelet-derived growth factor BB (PDGF-BB) enhanced phospholipase D (PLD) activity in a concentration dependent…”
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Mapping the effector region in Thermus thermophilus elongation factor Tu by Peter, Marcus E, Schirmer, Norbert K, Reiser, Christian O. A, Sprinzl, Mathias

“…Native elongation factor Tu from Thermus thermophilus is initially attacked by various endoproteases in a region spanning amino acid residues 40-70. By…”
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Interaction of the isolated domain II/III of Thermus thermophilus elongation factor Tu with the nucleotide exchange factor EF-Ts by PETER, M. E, REISER, C. O. A, SCHIRMER, N. K, KIEFHABER, T, OTT, G, GRILLENBECK, N. W, SPRINZL, M

“…The middle and C-terminal domain (domain II/III) of elongation factor Tu from Thermus thermophilus lacking the GTP/GDP binding domain have been prepared by…”
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Molecular cloning and nucleotide sequence of the gene encoding a H202‐forming NADH oxidase from the extreme thermophilic Thermus thermophilus HB8 and its expression in Escherichia coli by PARK, Ho‐Jin, KREUTZER, Roland, REISER, Christian O. A., SPRINZL, Mathias

“…The sequence of the 32 N‐terminal amino acids of the NADH oxidase from the extreme thermophile, Thermus thermophilus HB8, was used to synthesize…”
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Effect of Thermus thermophilus elongation factor Ts on the conformation of elongation factor Tu by SCHIRMER, Norbert K., REISER, Christian O. A., SPRINZL, Mathias

“…Affinity labeling in situ of the Thermus thermophilus elongation factor Tu (EF‐Tu) nucleotide binding site was achieved with periodate‐oxidized GDP (GDPoxi) or…”
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