Search Results - "Reis, Thiago A. R."

A urine-based ELISA with recombinant non-glycosylated SARS-CoV-2 spike protein for detecting anti-SARS-CoV-2 spike antibodies by Ramos, Fernanda F., Bagno, Flávia F., Vassallo, Paula F., Oliveira-da-Silva, João A., Reis, Thiago A. R., Bandeira, Raquel S., Machado, Amanda S., Lage, Daniela P., Martins, Vivian T., Fernandes, Ana P., Christodoulides, Myron, Ravetti, Cecilia G., Nobre, Vandack, da Fonseca, Flávio G., Coelho, Eduardo A. F., Ludolf, Fernanda

“…Serological assays have been widely used to detect anti-SARS-CoV-2 antibodies, which are generated from previous exposure to the virus or after vaccination…”
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Exploring drug repositioning for leishmaniasis treatment: Ivermectin plus polymeric micelles induce immunological response and protection against tegumentary leishmaniasis by Freitas, Camila S., Lage, Daniela P., Machado, Amanda S., Vale, Danniele L., Martins, Vívian T., Cardoso, Jamille M.O., Oliveira-da-Silva, João A., Reis, Thiago A.R., Tavares, Grasiele S.V., Ramos, Fernanda F., Ludolf, Fernanda, Pereira, Isabela A.G., Bandeira, Raquel S., Fujiwara, Ricardo T., Bueno, Lílian L., Roatt, Bruno M., Chávez-Fumagalli, Miguel A., Coelho, Eduardo A.F.

“…[Display omitted] •Drug repositioning was tested using ivermectin (IVE) against L. amazonensis.•It was incorporated into a Poloxamer P407®-containing polymeric…”
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Recombinant guanosine-5′-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection by Lage, Daniela P., Machado, Amanda S., Vale, Danniele L., Freitas, Camila S., Linhares, Flávia P., Cardoso, Jamille M.O., Pereira, Isabela A.G., Ramos, Fernanda F., Tavares, Grasiele S.V., Ludolf, Fernanda, Oliveira-da-Silva, João A., Bandeira, Raquel S., Silva, Alessandra M., Simões, Luciana C., Reis, Thiago A.R., Oliveira, Jamil S., Christodoulides, Myron, Chávez-Fumagalli, Miguel A., Roatt, Bruno M., Martins, Vívian T., Coelho, Eduardo A.F.

“…[Display omitted] •A GTP-binding protein was used as recombinant antigen against L. infantum.•It was associated with saponin or in polymeric micelles as…”
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Detecting anti-SARS-CoV-2 antibodies in urine samples: A noninvasive and sensitive way to assay COVID-19 immune conversion by Ludolf, Fernanda, Ramos, Fernanda F, Bagno, Flávia F, Oliveira-da-Silva, João A, Reis, Thiago A R, Christodoulides, Myron, Vassallo, Paula F, Ravetti, Cecilia G, Nobre, Vandack, da Fonseca, Flavio G, Coelho, Eduardo A F

“…Serum-based ELISA (enzyme-linked immunosorbent assay) has been widely used to detect anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis by Reis, Thiago A.R., Oliveira-da-Silva, João A., Tavares, Grasiele S.V., Mendonça, Débora V.C., Freitas, Camila S., Costa, Rafaella R., Lage, Daniela P., Martins, Vívian T., Machado, Amanda S., Ramos, Fernanda F., Silva, Alessandra M., Ludolf, Fernanda, Antinarelli, Luciana M.R., Brito, Rory C.F., Chávez-Fumagalli, Miguel A., Humbert, Maria V., Roatt, Bruno M., Coimbra, Elaine S., Coelho, Eduardo A.F.

“…Treatment for visceral leishmaniasis (VL) is hindered mainly by the toxicity and/or high cost of therapeutic drugs. In addition, parasite resistance has been…”
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Flau-A, a naphthoquinone derivative, is a promising therapeutic candidate against visceral leishmaniasis: A preliminary study by Mendonça, Débora V.C., Tavares, Grasiele S.V., Pereira, Isabela A.G., Oliveira-da-Silva, João A., Ramos, Fernanda F., Lage, Daniela P., Machado, Amanda S., Carvalho, Lívia M., Reis, Thiago A.R., Carvalho, Ana Maria R.S., Ottoni, Flaviano M., Ludolf, Fernanda, Freitas, Camila S., Martins, Vívian T., Chávez-Fumagalli, Miguel A., Duarte, Mariana C., Humbert, Maria V., Roatt, Bruno M., Menezes-Souza, Daniel, Alves, Ricardo J., Coelho, Eduardo A.F.

“…Visceral leishmaniasis (VL) is a neglected tropical disease found in tropical and subtropical regions in the world. The therapeutics used for the treatment…”
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Sensitive and specific serodiagnosis of tegumentary leishmaniasis using a new chimeric protein based on specific B-cell epitopes of Leishmania antigenic proteins by Galvani, Nathalia C., Machado, Amanda S., Lage, Daniela P., Martins, Vívian T., de Oliveira, Daysiane, Freitas, Camila S., Vale, Danniele L., Fernandes, Bruna B., Oliveira-da-Silva, João A., Reis, Thiago A.R., Santos, Thaís T.O., Ramos, Fernanda F., Bandeira, Raquel S., Ludolf, Fernanda, Tavares, Grasiele S.V., Guimarães, Nathalia S., Tupinambás, Unaí, Chávez-Fumagalli, Miguel A., Humbert, Maria V., Gonçalves, Denise U., Christodoulides, Myron, Machado-de-Ávila, Ricardo A., Coelho, Eduardo A.F.

“…Serological tests used for the diagnosis of tegumentary leishmaniasis (TL) presents problems, mainly related to their variable sensitivity and/or specificity,…”
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Potential of recombinant LiHyQ, a novel Leishmania infantum protein, for the diagnosis of canine visceral leishmaniasis and as a diagnostic and prognostic marker for human leishmaniasis and human immunodeficiency virus co-infection: A preliminary study by Santos, Thaís T.O., Ramos, Fernanda F., Gonçalves, Isabela A.P., Tavares, Grasiele S.V., Ludolf, Fernanda, Bandeira, Raquel S., Silva, Alessandra M., Oliveira-da-Silva, João A., Reis, Thiago A.R., Machado, Amanda S., Lage, Daniela P., Freitas, Camila S., Vale, Danniele L., Martins, Vívian T., Alves, Livia A., Guimarães, Nathalia S., Chaves, Ana Thereza, Chávez-Fumagalli, Miguel A., Cota, Gláucia F., Silveira, Julia A.G., Tupinambás, Unaí, Gonçalves, Denise U., Christodoulides, Myron, Coelho, Eduardo A.F.

“…•A new Leishmania protein classified as hypothetical was cloned, expressed and purified.•It was evaluated in ELISA experiments against 395 canine and human…”
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Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis by Oliveira-da-Silva, João A., Lage, Daniela P., Ramos, Fernanda F., Machado, Amanda S., Tavares, Grasiele S.V., Mendonça, Débora V.C., Pereira, Isabela A.G., Martins, Vívian T., Carvalho, Lívia M., Ludolf, Fernanda, Santos, Thaís T.O., Reis, Thiago A.R., Oliveira, Camila S., Bandeira, Raquel S., Silva, Alessandra M., Costa, Lourena E., Oliveira, Jamil S., Duarte, Mariana C., Menezes-Souza, Daniel, Roatt, Bruno M., Teixeira, Antônio L., Coelho, Eduardo A.F.

“…[Display omitted] •The pyridoxal kinase (PK) protein was evaluated against visceral leishmaniasis.•The protein was administered as a recombinant antigen or DNA…”
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A Leishmania amastigote-specific hypothetical protein evaluated as recombinant protein plus Th1 adjuvant or DNA plasmid-based vaccine to protect against visceral leishmaniasis by Oliveira-da-Silva, João A., Machado, Amanda S., Ramos, Fernanda F., Tavares, Grasiele S.V., Lage, Daniela P., Mendonça, Débora V.C., Pereira, Isabela A.G., Santos, Thaís T.O., Martins, Vívian T., Carvalho, Lívia M., Freitas, Camila S., Ludolf, Fernanda, Reis, Thiago A.R., Bandeira, Raquel S., Silva, Alessandra M., Costa, Lourena E., Oliveira, Jamil S., Duarte, Mariana C., Roatt, Bruno M., Teixeira, Antônio L., Coelho, Eduardo A.F.

“…[Display omitted] •A Leishmania amastigote-specific protein was evaluated as vaccine against VL.•The protein was administered as a recombinant antigen or as…”
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Biotechnological applications from a Leishmania amastigote-specific hypothetical protein in the canine and human visceral leishmaniasis by Oliveira-da-Silva, João A., Machado, Amanda S., Tavares, Grasiele S.V., Ramos, Fernanda F., Lage, Daniela P., Ludolf, Fernanda, Steiner, Bethina T., Reis, Thiago A.R., Santos, Thaís T.O., Costa, Lourena E., Bandeira, Raquel S., Martins, Vívian T., Galvani, Nathália C., Chaves, Ana T., Oliveira, Jamil S., Chávez-Fumagalli, Miguel A., Tupinambás, Unaí, de Magalhães-Soares, Danielle F., Silveira, Julia A.G., Lyon, Sandra, Machado-de-Ávila, Ricardo A., Coelho, Eduardo A.F.

“…The treatment against visceral leishmaniasis (VL) presents problems, mainly related to the toxicity and/or high cost of the drugs. In this context, a rapid and…”
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Leishmania eukaryotic elongation Factor-1 beta protein is immunogenic and induces parasitological protection in mice against Leishmania infantum infection by Santos, Thaís T.O., Machado, Amanda S., Ramos, Fernanda F., Oliveira-da-Silva, João A., Lage, Daniela P., Tavares, Grasiele S.V., Mendonça, Débora V.C., Cardoso, Mariana S., Siqueira, Williane F., Martins, Vívian T., Ludolf, Fernanda, Reis, Thiago A.R., Carvalho, Lívia M., Freitas, Camila S., Bandeira, Raquel S., Silva, Alessandra M., Oliveira, Jamil S., Moreira, Ricardo L.F., Fujiwara, Ricardo T., Roatt, Bruno M., Chávez-Fumagalli, Miguel A., Humbert, Maria V., Teixeira, Antônio L., Coelho, Eduardo A.F.

“…Treatment for visceral leishmaniasis (VL) is hampered mainly by the toxicity and/or high cost of antileishmanial drugs. What is more, variability on…”
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ChimLeish, a new recombinant chimeric protein evaluated as a diagnostic and prognostic marker for visceral leishmaniasis and human immunodeficiency virus coinfection by Galvani, Nathalia C., Machado, Amanda S., Lage, Daniela P., Freitas, Camila S., Vale, Danniele L., de Oliveira, Daysiane, Ludolf, Fernanda, Ramos, Fernanda F., Fernandes, Bruna B., Luiz, Gabriel P., Mendonça, Débora V. C., Oliveira-da-Silva, João A., Reis, Thiago A. R., Tavares, Grasiele S. V., Chaves, Ana T., Guimarães, Nathalia S., Tupinambás, Unaí, Cota, Gláucia F., Humbert, Maria V., Martins, Vívian T., Christodoulides, Myron, Coelho, Eduardo A. F., Machado-de-Ávila, Ricardo A.

“…Visceral leishmaniasis (VL) is a neglected tropical disease of global importance caused by parasites of the genus Leishmania , and coinfection with human…”
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Diagnostic application of sensitive and specific phage-exposed epitopes for visceral leishmaniasis and human immunodeficiency virus coinfection by Ramos, Fernanda F., Tavares, Grasiele S. V., Ludolf, Fernanda, Machado, Amanda S., Santos, Thaís T. O., Gonçalves, Isabela A. P., Dias, Ana C. S., Alves, Patrícia T., Fraga, Vanessa G., Bandeira, Raquel S., Oliveira-da-Silva, João A., Reis, Thiago A. R., Lage, Daniela P., Martins, Vívian T., Freitas, Camila S., Chaves, Ana T., Guimarães, Nathalia S., Chávez-Fumagalli, Miguel A., Tupinambás, Unaí, Rocha, Manoel O. C., Cota, Gláucia F., Fujiwara, Ricardo T., Bueno, Lílian L., Goulart, Luiz Ricardo, Coelho, Eduardo A. F.

“…The diagnosis of visceral leishmaniasis (VL) has improved with the search of novel antigens; however, their performance is limited when samples from VL/human…”
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Corrigendum to “Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis”. Molecular Immunology 124 (2020) 161–171 by Oliveira-da-Silva, João A., Lage, Daniela P., Ramos, Fernanda F., Machado, Amanda S., Tavares, Grasiele S.V., Mendonça, Débora V.C., Pereira, Isabela A.G., Martins, Vívian T., Carvalho, Lívia M., Ludolf, Fernanda, Santos, Thaís T.O., Reis, Thiago A.R., Freitas, Camila S., Bandeira, Raquel S., Silva, Alessandra M., Costa, Lourena E., Oliveira, Jamil S., Duarte, Mariana C., Roatt, Bruno M., Teixeira, Antônio L., Coelho, Eduardo A.F.

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Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis by Costa, Rafaella R., Oliveira-da-Silva, João A., Reis, Thiago A. R., Tavares, Grasiele S. V., Mendonça, Débora V. C., Freitas, Camila S., Lage, Daniela P., Martins, Vívian T., Antinarelli, Luciana M. R., Machado, Amanda S., Bandeira, Raquel S., Ludolf, Fernanda, Santos, Thaís T. O., Brito, Rory C. F., Humbert, Maria V., Menezes-Souza, Daniel, Duarte, Mariana C., Chávez-Fumagalli, Miguel A., Roatt, Bruno M., Coimbra, Elaine S., Coelho, Eduardo A. F.

“…Treatment against visceral leishmaniasis (VL) is mainly hampered by drug toxicity, long treatment regimens and/or high costs. Thus, the identification of novel…”
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Evaluation of Leishmania infantum pyridoxal kinase protein for the diagnosis of human and canine visceral leishmaniasis by Oliveira-da-Silva, João A., Machado, Amanda S., Ramos, Fernanda F., Tavares, Grasiele S.V., Lage, Daniela P., Ludolf, Fernanda, Steiner, Bethina T., Reis, Thiago A.R., Santos, Thaís T.O., Costa, Lourena E., Martins, Vívian T., Galvani, Nathália C., Chaves, Ana T., Oliveira, Jamil S., Chávez-Fumagalli, Miguel A., de Magalhães-Soares, Danielle F., Duarte, Mariana C., Menezes-Souza, Daniel, Silveira, Julia A.G., Moreira, Ricardo L.F., Machado-de-Ávila, Ricardo A., Tupinambás, Unaí, Gonçalves, Denise U., Coelho, Eduardo A.F.

“…[Display omitted] •The Leishmania pyridoxal kinase (PK) protein was used to diagnose VL.•A specific B cell epitope of the PK protein was predicted and…”
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A clioquinol-containing Pluronic ® F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model by Tavares, Grasiele S V, Mendonça, Débora V C, Pereira, Isabela A G, Oliveira-da-Silva, João A, Ramos, Fernanda F, Lage, Daniela P, Machado, Amanda S, Carvalho, Lívia M, Reis, Thiago A R, Perin, Luísa, Carvalho, Ana Maria R S, Ottoni, Flaviano M, Ludolf, Fernanda, Freitas, Camila S, Bandeira, Raquel S, Silva, Alessandra M, Chávez-Fumagalli, Miguel A, Duarte, Mariana C, Menezes-Souza, Daniel, Alves, Ricardo J, Roatt, Bruno M, Coelho, Eduardo A F

“…A clioquinol (ICHQ)-containing Pluronic F127 polymeric micelle system (ICHQ/Mic) was recently shown to be effective against Leishmania amazonensis infection in…”
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