Search Results - "Reis, Patrícia P."
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Tomato (Lycopersicon esculentum) or lycopene supplementation attenuates ventricular remodeling after myocardial infarction through different mechanistic pathways
Published in The Journal of nutritional biochemistry (01-08-2017)“…The objective of this study was to evaluate the influence of tomato or lycopene supplementation on cardiac remodeling after myocardial infarction (MI). Male…”
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Tomato (Lycopersicon esculentum) Supplementation Induces Changes in Cardiac miRNA Expression, Reduces Oxidative Stress and Left Ventricular Mass, and Improves Diastolic Function
Published in Nutrients (19-11-2015)“…The aim of this study was to evaluate the effects of tomato supplementation on the normal rat heart and the role of oxidative stress in this scenario. Male…”
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3
mRNA transcript quantification in archival samples using multiplexed, color-coded probes
Published in BMC biotechnology (09-05-2011)“…A recently developed probe-based technology, the NanoString nCounter™ gene expression system, has been shown to allow accurate mRNA transcript quantification…”
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4
Comprehensive Analysis of Lung Adenocarcinoma and Brain Metastasis through Integrated Single-Cell Transcriptomics
Published in International journal of molecular sciences (01-04-2024)“…Lung adenocarcinoma (LUAD) is a highly prevalent and lethal form of lung cancer, comprising approximately half of all cases. It is often diagnosed at advanced…”
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Mechanisms Contributing to the Comorbidity of COPD and Lung Cancer
Published in International journal of molecular sciences (02-02-2023)“…Lung cancer and chronic obstructive pulmonary disease (COPD) often co-occur, and individuals with COPD are at a higher risk of developing lung cancer. While…”
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A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence
Published in BMC cancer (11-10-2011)“…Oral Squamous Cell Carcinoma (OSCC) is a major cause of cancer death worldwide, which is mainly due to recurrence leading to treatment failure and patient…”
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Liquid Biopsy in Lung Cancer: Biomarkers for the Management of Recurrence and Metastasis
Published in International journal of molecular sciences (17-05-2023)“…Liquid biopsies have emerged as a promising tool for the detection of metastases as well as local and regional recurrence in lung cancer. Liquid biopsy tests…”
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Integration of miRNA and mRNA expression profiles reveals microRNA-regulated networks during muscle wasting in cardiac cachexia
Published in Scientific reports (01-08-2017)“…Cardiac cachexia (CC) is a common complication of heart failure (HF) associated with muscle wasting and poor patient prognosis. Although different mechanisms…”
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Editorial: Human and Oncoviral Non-Coding RNAs as Modulators of Cancer Aggressiveness and Disease Progression
Published in Frontiers in oncology (25-01-2021)Get full text
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Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma
Published in Molecular cancer (10-09-2010)“…The tumor suppressor Programmed Cell Death 4 (PDCD4) has been found to be under-expressed in several cancers and associated with disease progression and…”
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Extracellular Vesicle-Packaged miR-195-5p Sensitizes Melanoma to Targeted Therapy with Kinase Inhibitors
Published in Cells (Basel, Switzerland) (05-05-2023)“…Management of advanced melanoma remains challenging, with most BRAF (B-Raf proto-oncogene, serine/threonine kinase)-mutated metastatic patients relapsing…”
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The Complex Role of the Microbiome in Non-Small Cell Lung Cancer Development and Progression
Published in Cells (Basel, Switzerland) (01-12-2023)“…In recent years, there has been a growing interest in the relationship between microorganisms in the surrounding environment and cancer cells. While the tumor…”
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Genetic and Epigenetic Mechanisms Deregulate the CRL2pVHL Complex in Hepatocellular Carcinoma
Published in Frontiers in genetics (18-05-2022)“…Dysregulation of ubiquitin-proteasome pathway genes through copy number alteration, promoter hypomethylation, and miRNA deregulation is involved in cancer…”
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Typical Lung Carcinoids with Metastasis: Potential Role of MicroRNAs in the Regulation of Adaptive Immunity Associated with Disease: a Case Study
Published in Cellular physiology and biochemistry (06-01-2021)“…Lung carcinoids are uncommon neuroendocrine tumours. Molecular features of lung carcinoids have been poorly defined. microRNAs (miRNAs) are potent gene…”
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MicroRNA Signature Obtained From the Comparison of Aggressive With Indolent Non-Hodgkin Lymphomas: Potential Prognostic Value in Mantle-Cell Lymphoma
Published in Journal of clinical oncology (10-08-2013)“…Mantle-cell lymphoma (MCL) has a variable natural history but is incurable with current therapies. MicroRNAs (miRs) are useful in prognostic assessment of…”
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Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility
Published in Non-coding RNA (01-10-2023)“…Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been…”
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microRNA-mRNA Networks Linked to Inflammation and Immune System Regulation in Inflammatory Bowel Disease
Published in Biomedicines (01-02-2024)“…The molecular processes linked to the development and progression of Crohn's disease (CD) and ulcerative colitis (UC) are not completely understood. MicroRNAs…”
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Large-scale discovery of previously undetected microRNAs specific to human liver
Published in Human genomics (27-03-2018)“…MicroRNAs (miRNAs) are crucial regulators of gene expression in normal development and cellular homeostasis. While miRNA repositories contain thousands of…”
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Orange Juice Attenuates Circulating miR-150-5p, miR-25-3p, and miR-451a in Healthy Smokers: A Randomized Crossover Study
Published in Frontiers in nutrition (Lausanne) (24-12-2021)“…Tobacco smoke is associated with oxidative and inflammatory pathways, increasing the risk of chronic-degenerative diseases. Our goal was to evaluate the…”
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microRNA evaluation of unknown primary lesions in the head and neck
Published in Molecular cancer (23-12-2009)“…Unknown primary malignancy in the head and neck is not an infrequent diagnosis for patients with metastatic cervical lymph nodes. Although linked with a…”
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