Comparative study of the effects of the Ga-As (904 nm, 150mW) laser and the pulsed ultrasound of 1 MHz in inflammation of tibialis muscle of Wistar rats

This paper aims to compare the therapeutic effect of the laser As-Ga of 904nm and pulsed Ultrasound of 1 MHz applied in striated skeletal muscle of inflamed rats. The animals received an intramuscular injection of bupivacaine hydrochloride in tibialis muscle in order to induce the inflammatory proce...

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Published in:Brazilian archives of biology and technology Vol. 51; no. spe; pp. 225 - 230
Main Authors: Pinto, Marcus Vinícius de Mello, Costa, Daniel Almeida da, Rocha, Lamara Laguardia Valente, Santos, Hélio Ricardo dos, Silva, André Luis dos Santos, Barbosa, Luis Guilherme, Reis, João Batista Alves dos, Bernardo-Filho, Mario
Format: Journal Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 01-12-2008
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Summary:This paper aims to compare the therapeutic effect of the laser As-Ga of 904nm and pulsed Ultrasound of 1 MHz applied in striated skeletal muscle of inflamed rats. The animals received an intramuscular injection of bupivacaine hydrochloride in tibialis muscle in order to induce the inflammatory process, and after 24 hours, the time was considered 0 for the initiation of therapy, using a laser and ultrasound. Samples collected the muscles of the animals were stained with Hematoxylin-Eosin and histological sections of the groups used for the analysis of the muscle tissue in relation to reducing the inflammatory process, comparing the results of the two therapies used. In this study it is suggested that both treatment with laser as with ultrasound can act as anti-inflammatory. However, the laser seems to have anti-inflammatory effect for all periods observed, while the ultrasound was only able to induce declining inflammatory response to seven days. O presente trabalho tem como objetivo comparar o efeito terapêutico do Laser As-Ga de 904nm e do Ultra-som pulsado de 1 MHz aplicado em músculo estriado esquelético inflamado de ratos Wistar. Os animais receberam uma injeção intramuscular de cloridrato de bupivacaína no músculo tibial, a fim de induzir o processo inflamatório, e após 24 horas, foi considerado o tempo 0 para o início da terapia, utilizando-se o laser e o ultra-som. As amostras coletadas dos músculos dos 35 animais foram coradas com Hematoxilina-Eosina e as secções histológicas dos grupos serviram para as análises do tecido muscular em relação à redução do processo inflamatório, comparando os resultados das duas terapias utilizadas. Neste trabalho sugere-se que tanto os tratamentos com laser quanto com ultra-som podem agir como antiinflamatórios, no entanto, o laser parece ter efeito antiinflamatório durante todos os períodos observados, enquanto o ultra-som somente foi capaz de induzir diminuição da resposta inflamatória aos sete dias.
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ISSN:1516-8913
1516-8913
1678-4324
DOI:10.1590/S1516-89132008000700037