Search Results - "Reis, Donald"

Agmatine: An Endogenous Clonidine-Displacing Substance in the Brain by Li, Gen, Regunathan, S., Barrow, Colin J., Eshraghi, Jamshid, Cooper, Raymond, Reis, Donald J.

“…Clonidine, an antihypertensive drug, binds to $\alpha_2$-adrenergic and imidazoline receptors. The endogenous ligand for imidazoline receptors may be a…”
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Is agmatine a novel neurotransmitter in brain? by Reis, Donald J, Regunathan, Soundararajan

“…Recent evidence suggests that agmatine, which is an intermediate in polyamine biosynthesis, might be an important neurotransmitter in mammals. Agmatine is…”
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Induction of Calcium-Independent Nitric Oxide Synthase Activity in Primary Rat Glial Cultures by Galea, Elena, Feinstein, Douglas L., Reis, Donald J.

“…Exposure of primary cultures of neonatal rat cortical astrocytes to bacterial lipopolysaccharide (LPS) results in the appearance of nitric oxide synthase (NOS)…”
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Neurons of a Limited Subthalamic Area Mediate Elevations in Cortical Cerebral Blood Flow Evoked by Hypoxia and Excitation of Neurons of the Rostral Ventrolateral Medulla by Golanov, Eugene V, Christensen, John R. C, Reis, Donald J

“…Sympathoexcitatory reticulospinal neurons of the rostral ventrolateral medulla (RVLM) are oxygen detectors excited by hypoxia to globally elevate regional…”
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Anatomical substrates for baroreflex sympathoinhibition in the rat by Aicher, Sue A, Milner, Teresa A, Pickel, Virginia M, Reis, Donald J

“…The fundamental neuronal substrates of the arterial baroreceptor reflex have been elucidated by combining anatomical, neurophysiological, and pharmacological…”
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Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia by Glickstein, Sara B, Ilch, Christopher P, Reis, Donald J, Golanov, Eugene V

“…We investigated whether stimulation of the functionally discrete subthalamic region, subthalamic cerebrovasodilator area (SVA), which increases cerebral blood…”
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Neurons of nucleus of the solitary tract synchronize the EEG and elevate cerebral blood flow via a novel medullary area by Golanov, Eugene V., Reis, Donald J.

“…In anesthetized spinalized rat, electrical stimulation of the nucleus tractus solitarius (NTS) synchronizes the EEG by increasing the power of 4–6-Hz waves…”
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Agmatine Reverses Pain Induced by Inflammation, Neuropathy, and Spinal Cord Injury by Fairbanks, Carolyn A., Schreiber, Kristin L., Brewer, Kori L., Yu, Chen-Guang, Stone, Laura S., Kitto, Kelley F., Nguyen, H. Oanh, Grocholski, Brent M., Shoeman, Don W., Kehl, Lois J., Regunathan, Soundararajan, Reis, Donald J., Yezierski, Robert P., Wilcox, George L.

“…Antagonists of glutamate receptors of the N-methyl-D-aspartate subclass (NMDAR) or inhibitors of nitric oxide synthase (NOS) prevent nervous system plasticity…”
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Brief electrical stimulation of cerebellar fastigial nucleus conditions long-lasting salvage from focal cerebral ischemia: conditioned central neurogenic neuroprotection by Reis, Donald J, Kobylarz, Keith, Yamamoto, Seiji, Golanov, Eugene V

“…The cerebellar fastigial nucleus (FN) was electrically stimulated for 1 h in anesthetized rats and the middle cerebral artery occluded at various times…”
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Electrical stimulation of cerebellar fastigial nucleus protects rat brain, in vitro, from staurosporine‐induced apoptosis by Zhou, Ping, Qian, Liping, Glickstein, Sara B., Golanov, Eugene V., Pickel, Virginia M., Reis, Donald J.

“…Electrical stimulation of the cerebellar fastigial nucleus (FN) elicits a prolonged (∼10 days) and substantial (50–80%) protection against ischemic and…”
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Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine by Galea, E, Regunathan, S, Eliopoulos, V, Feinstein, D L, Reis, D J

“…Agmatine, decarboxylated arginine, is a metabolic product of mammalian cells. Considering the close structural similarity between L-arginine and agmatine, we…”
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A brainstem area mediating cerebrovascular and EEG responses to hypoxic excitation of rostral ventrolateral medulla in rat by Golanov, Eugene V., Ruggiero, David A., Reis, Donald J.

“…We sought to identify the medullary relay area mediating the elevations of regional cerebral blood flow (rCBF) and synchronization of the electroencephalogram…”
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Intrinsic Neurons of Fastigial Nucleus Mediate Neurogenic Neuroprotection against Excitotoxic and Ischemic Neuronal Injury in Rat by Glickstein, Sara B, Golanov, Eugene V, Reis, Donald J

“…Electrical stimulation of the cerebellar fastigial nucleus (FN) elevates regional cerebral blood flow (rCBF) and arterial pressure (AP) and provides…”
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Cerebellar stimulation reduces inducible nitric oxide synthase expression and protects brain from ischemia by Galea, E, Golanov, E V, Feinstein, D L, Kobylarz, K A, Glickstein, S B, Reis, D J

“…A focal infarction produced by occlusion of the middle cerebral artery (MCAO) in spontaneously hypertensive rats induced expression of inducible nitric oxide…”
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Agmatine containing axon terminals in rat hippocampus form synapses on pyramidal cells by Reis, Donald J, Yang, Xian-Cheng, Milner, Teresa A

“…We examined the cellular and subcellular localization of agmatine in the hippocampal CA1 region by immunocytochemistry. By light microscopy, agmatine-like…”
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Neuroprotective electrical stimulation of cerebellar fastigial nucleus attenuates expression of periinfarction depolarizing waves (PIDs) and inhibits cortical spreading depression by Golanov, Eugene V, Reis, Donald J

“…In rat, electrical stimulation of the cerebellar fastigial nucleus (FN) for 1 h reduces the volume of focal ischemic infarctions produced by occluding the…”
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Specific actions of cyanide on membrane potential and voltage-gated ion currents in rostral ventrolateral medulla neurons in rat brainstem slices by Wang, Gang, Zhou, Ping, Repucci, Michael A, Golanov, Eugene V, Reis, Donald J

“…The present study examined specific effects of sodium cyanide (CN) on the membrane potential (MP), spontaneous discharge (SD) and voltage-gated ion current of…”
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Stimulation of Imidazoline Receptors Inhibits Proliferation of Human Coronary Artery Vascular Smooth Muscle Cells by Regunathan, Soundararajan, Reis, Donald J

“…Vascular smooth muscle cells of rat aorta express imidazoline receptors whose stimulation, by drugs or an endogenous ligand, agmatine, inhibits…”
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Synthesis of nitric oxide in CNS glial cells by Murphy, S, Simmons, M L, Agullo, L, Garcia, A, Feinstein, D L, Galea, E, Reis, D J, Minc-Golomb, D, Schwartz, J P

“…Attention has focused on particular neurons as the source of nitric oxide (NO) within the parenchyma of the CNS. In contrast, glial cells have been viewed…”
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Evidence for endogenous agmatine in hypothalamo-neurohypophysial tract and its modulation on vasopressin release and Ca2+ channels by GANG WANG, GORBATYUK, Oleg S, DAYANITHI, Govindan, WEI OUYANG, JIALING WANG, MILNER, Teresa A, REGUNATHAN, Soundar, REIS, Donald J

“…Agmatine, decarboxylated from arginine by arginine decarboxylase, is particularly prominent in the hypothalamus. The present study utilized the rat…”
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