Search Results - "Reinstein, J"

Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding by Müller, CW, Schlauderer, GJ, Reinstein, J, Schulz, GE

“…Background: Adenylate kinases undergo large conformational changes during their catalytic cycle. Because these changes have been studied by comparison of…”
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The DnaK/ClpB chaperone system from Thermus thermophilus by Schlee, S, Reinstein, J

“…Proteins of thermophilic organisms are adapted to remain well structured and functional at elevated temperatures. Nevertheless like their 'cousins' that reside…”
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Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli by Reinstein, Jochen, Brune, Martin, Wittinghofer, Alfred

“…The adk gene of Escherichia coli has been used to overexpress the adenylate kinase protein in two ways: (1) by cloning the adk gene with its own promoter into…”
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Percutaneous endoscopic gastrostomy vs surgical gastrostomy in infants with congenital heart disease by Einhorn, Lisa M., Taicher, Brad M., Greene, Nathaniel H., Reinstein, Leon J., Jooste, Edmund H., Campbell, Michael J., Machovec, Kelly A.

“…Summary Background Infants with congenital heart disease often require feeding tube placement to supplement oral intake. Gastrostomy tubes may be placed by…”
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A novel, point-of-care test for Lithium levels: Description and reliability by GLAZER, William M, SONNENBERG, John G, REINSTEIN, Michael J, AKERS, Raymond F

“…Lithium is a highly effective agent for numerous psychiatric disorders but requires therapeutic monitoring because of its narrow therapeutic index. This…”
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Evaluation of the Use of Botulinum Toxin in Children With Achalasia by Hurwitz, Melissa, Bahar, Ron J, Ament, Marvin E, Tolia, Vasundhara, Molleston, Jean, Reinstein, L Julio, Walton, J Mark, Erhart, Nora, Wasserman, Dror, Justinich, Christopher, Vargas, Jorge

“…BACKGROUNDAchalasia is rare in children. Recently, injection of botulinum toxin into the lower esophageal sphincter has been studied as an alternative to…”
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10580 Surgical Approach to Hysterectomy with Obliterated Cul-De-Sac by Clark, NM, Parikh, S, Hanna, H, Reinstein, J, Connor, A, Webber, VE

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Paradoxical reactions in children associated with midazolam use during endoscopy by Massanari, M, Novitsky, J, Reinstein, L J

“…All 2,617 children who received midazolam and meperidine for a variety of endoscopic procedures were monitored for the development of adverse behavioral…”
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p21 with a phenylalanine 28----leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties by REINSTEIN, J, SCHLICHTING, I, FRECH, M, GOODY, R. S, WITTINGHOFER, A

“…The H-ras gene product p21H has been mutated at Phe-28, which makes a hydrophobic interaction with the guanine base of bound GDP/GTP. The mutation Phe-28---Leu…”
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Illumination for ultrafast pump probe experiments by serial femtosecond crystallography by Grünbein, M.L., Stricker, M., Kovacs, G.N., Kloos, M., Doak, R.B., Shoeman, R.L, Reinstein, J., Lecler, Sylvain, Haacke, Stefan, Schlichting, I.

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Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells by Reinstein, L J, Lichtman, S N, Currin, R T, Wang, J, Thurman, R G, Lemasters, J J

“…In liver grafts that will fail as a result of storage injury, reperfusion activates Kupffer cells. Overproduction of tumor necrosis factor by activated Kupffer…”
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Novel Nucleotide Analogues as Potential Substrates for TMPK, a Key Enzyme in the Metabolism of AZT by Müller, H. C., Meier, C., Balzarini, J., Reinstein, J.

“…Novel cyclic and acyclic analogues of dTMP and AZTMP were synthesized from the corresponding cycloSal-phosphotriesters. This method yielded the nucleotides in…”
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Oxcarbazepine versus Divalproex Sodium for the Continuing Treatment of Mania by Reinstein, Michael J, Sonnenberg, John G, Hedberg, Thomas G, Jones, Lynne E, Reyngold, Polina

“…Oxcarbazepine, an antiepileptic and a derivative of carbamazepine, has been shown to have clinical utility as an antimanic agent. This study sought to assess…”
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Crystal Structures of the AppA BLUF Domain Photoreceptor Provide Insights into Blue Light-mediated Signal Transduction by Jung, Astrid, Reinstein, Jochen, Domratcheva, Tatiana, Shoeman, Robert L., Schlichting, Ilme

“…Proteins containing a sensor of blue light using FAD (BLUF) domain control diverse cellular processes, such as gene expression, nucleotide metabolism and…”
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The novel fluorescent CDP-analogue (Pβ)MABA-CDP is a specific probe for the NMP binding site of UMP/CMP kinase by RUDOLPH, MARKUS G., VEIT, THOMAS J.H., REINSTEIN, JOCHEN

“…Direct thermodynamic and kinetic investigations of the binding of nucleotides to the nucleoside monophosphate (NMP) site of NMP kinases have not been possible…”
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Fluorescence and NMR investigations on the ligand binding properties of adenylate kinases by Reinstein, Jochen, Vetter, Ingrid R, Schlichting, Ilme, Roesch, Paul, Wittinghofer, Alfred, Goody, Roger S

“…A new system for measurement of affinities of adenylate kinases (AK) for substrates and inhibitors is presented. This system is based on the use of the…”
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Coupling and Dynamics of Subunits in the Hexameric AAA+ Chaperone ClpB by Werbeck, Nicolas D., Schlee, Sandra, Reinstein, Jochen

“…The bacterial AAA+ protein ClpB and its eukaryotic homologue Hsp104 ensure thermotolerance of their respective organisms by reactivating aggregated proteins in…”
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Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation by Lavie, Arnon, Vetter, Ingrid R, Konrad, Manfred, Goody, Roger S, Reinstein, Jochen, Schlichting, Ilme

“…Structural comparison of thymidylate kinase complexed with either dTMP or with AZTMP suggests that the low phosphorylation rate of AZTMP is due to an induced…”
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Sti1 is a non-competitive inhibitor of the Hsp90 ATPase. Binding prevents the N-terminal dimerization reaction during the atpase cycle by Richter, Klaus, Muschler, Paul, Hainzl, Otmar, Reinstein, Jochen, Buchner, Johannes

“…The molecular chaperone Hsp90 is known to be involved in the activation of key regulatory proteins such as kinases, steroid hormone receptors, and…”
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Comparative Efficacy and Tolerability of Benzatropine and Terazosin in the Treatment of Hypersalivation Secondary to Clozapine by Reinstein, Michael J., Sirotovskaya, Larissa A., Chasanov, Maxim A., Jones, Lynne E., Mohan, Sangarapillai

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