Search Results - "Reinsmoen, Nancy"

Compelling scientific and clinical evidence that non-HLA specific antibodies impact graft outcome independently and in concert with donor HLA specific antibodies by Reinsmoen, Nancy L.

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HLA Mismatches Identified by a Novel Algorithm Predict Risk of Antibody-mediated Rejection From De Novo Donor-specific Antibodies by Zhang, Xiaohai, Reinsmoen, Nancy L, Kobashigawa, Jon A

“…The development of de novo donor-specific antibodies (dnDSA) and antibody-mediated rejection (AMR) remains a barrier to long-term graft and patient survival…”
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Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation by Levine, Deborah J., Glanville, Allan R., Aboyoun, Christina, Belperio, John, Benden, Christian, Berry, Gerald J., Hachem, Ramsey, Hayes, Don, Neil, Desley, Reinsmoen, Nancy L., Snyder, Laurie D., Sweet, Stuart, Tyan, Dolly, Verleden, Geert, Westall, Glen, Yusen, Roger D., Zamora, Martin, Zeevi, Adriana

“…Antibody-mediated rejection (AMR) is a recognized cause of allograft dysfunction in lung transplant recipients. Unlike AMR in other solid-organ transplant…”
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Immunological Risk Stratification by Assessing Both the HLA and Non-HLA-Specific Antibodies: Time to Include Testing for Non-HLA Antibodies in the Routine Clinical Antibody Analysis Profile? by Reinsmoen, Nancy L

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Role of angiotensin II type 1 receptor-activating antibodies in solid organ transplantation by Reinsmoen, Nancy L

“…Abstract Angiotensin type I receptor (AT1 R) mediates physiologic and pathophysiologic actions of its ligand, angiotensin II. Overactivity of the AT1 R and…”
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Angiotensin II type I receptor antibodies in thoracic transplantation by Zhang, Xiaohai, Reinsmoen, Nancy L.

“…Angiotensin II type I receptor (AT1R) is a critical player in regulating vasoconstriction, blood pressure, sodium retention. Even though AT1R has limited…”
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Differences in pathologic features and graft outcomes in antibody-mediated rejection of renal allografts due to persistent/recurrent versus de novo donor-specific antibodies by Haas, Mark, Mirocha, James, Reinsmoen, Nancy L, Vo, Ashley A, Choi, Jua, Kahwaji, Joseph M, Peng, Alice, Villicana, Rafael, Jordan, Stanley C

“…Antibody-mediated rejection (ABMR) of renal allografts occurs in two forms. Type 1 ABMR results from persistence and/or a rebound of preexisting donor-specific…”
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Impact of Non-Human Leukocyte Antigen-Specific Antibodies in Kidney and Heart Transplantation by Zhang, Xiaohai, Reinsmoen, Nancy L

“…The presence of donor human leukocyte antigen (HLA)-specific antibodies has been shown to be associated with graft loss and decreased patient survival, but it…”
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A 3-Center Study Reveals New Insights Into the Impact of Non-HLA Antibodies on Lung Transplantation Outcome by Reinsmoen, Nancy L, Mirocha, James, Ensor, Christopher R, Marrari, Marilyn, Chaux, George, Levine, Deborah J, Zhang, Xiaohai, Zeevi, Adriana

“…The presence of antibodies to angiotensin type 1 receptor (AT1R) and endothelin type A receptor (ETAR) is associated with allograft rejection in kidney and…”
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Impact and production of Non‐HLA‐specific antibodies in solid organ transplantation by Zhang, Xiaohai, Reinsmoen, Nancy L.

“…Organ transplantation is an effective way to treat end‐stage organ disease. Extending the graft survival is one of the major goals in the modern era of organ…”
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Comprehensive assessment for serum treatment for single antigen test for detection of HLA antibodies by Zhang, Xiaohai, Reinsmoen, Nancy L.

“…The single antigen test is widely used in the field of transplantation to determine the specificity of HLA antibodies. It will be beneficial to standardize the…”
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Revision of the 1996 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Lung Rejection by Stewart, Susan, FRCPath, Fishbein, Michael C., MD, Snell, Gregory I., MD, Berry, Gerald J., MD, Boehler, Annette, MD, Burke, Margaret M., FRCPath, Glanville, Alan, MD, Gould, F. Kate, FRCPath, Magro, Cynthia, MD, Marboe, Charles C., MD, McNeil, Keith D., FRACP, Reed, Elaine F., PhD, Reinsmoen, Nancy L., PhD, Scott, John P., MD, Studer, Sean M., MD, Tazelaar, Henry D., MD, Wallwork, John L., FRCS, Westall, Glen, MD, Zamora, Martin R., MD, Zeevi, Adriana, PhD, Yousem, Samuel A., MD

“…In 1990, an international grading scheme for the grading of pulmonary allograft rejection was adopted by the International Society for Heart and Lung…”
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Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation by Vo, Ashley A, Lukovsky, Marina, Toyoda, Mieko, Wang, Jennifer, Reinsmoen, Nancy L, Lai, Chih-Hung, Peng, Alice, Villicana, Rafael, Jordan, Stanley C

“…This open-label, phase 1–2, single-center study examined the use of intravenous immune globulin and rituximab to reduce anti-HLA antibodies and improve…”
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Increased Negative Impact of Donor HLA-Specific Together With Non-HLA–Specific Antibodies on Graft Outcome by Reinsmoen, Nancy L, Lai, Chih-Hung, Mirocha, James, Cao, Kai, Ong, Geraldine, Naim, Mehrnoush, Wang, Qi, Haas, Mark, Rafiei, Matthew, Czer, Lawrence, Patel, Jignesh, Kobashigawa, Jon

“…BACKGROUNDDe novo donor HLA-specific (dnDSA) and non-HLA antibodies including antiangiotensin type 1 receptor antibodies (AT1R-abs) have been associated with…”
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Use of Intravenous Immune Globulin and Rituximab for Desensitization of Highly HLA-Sensitized Patients Awaiting Kidney Transplantation by VO, Ashley A, PENG, Alice, TOYODA, Mieko, KAHWAJI, Joseph, KAI CAO, LAI, Chih-Hung, REINSMOEN, Nancy L, VILLICANA, Rafael, JORDAN, Stanley C

“…BACKGROUND.: We have shown that high-dose intravenous immune globulin (IVIG; 2 g/kg x2 doses)+rituximab (1 g x2 doses) was effective in lowering anti-human…”
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A Phase I/II Placebo-Controlled Trial of C1-Inhibitor for Prevention of Antibody-Mediated Rejection in HLA Sensitized Patients by Vo, Ashley A, Zeevi, Adriana, Choi, Jua, Cisneros, Kristen, Toyoda, Mieko, Kahwaji, Joseph, Peng, Alice, Villicana, Rafael, Puliyanda, Dechu, Reinsmoen, Nancy, Haas, Mark, Jordan, Stanley C

“…BACKGROUNDAntibody-mediated rejection (AMR) is a severe form of rejection, mediated primarily by antibody-dependent complement (C) activation. C1 inhibitor…”
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Implications for human leukocyte antigen antibodies after lung transplantation: a 10-year experience in 441 patients by Snyder, Laurie D, Wang, Ziwei, Chen, Dong-Feng, Reinsmoen, Nancy L, Finlen-Copeland, C Ashley, Davis, W Austin, Zaas, David W, Palmer, Scott M

“…Long-term survival after lung transplant is limited by the development of chronic and progressive airflow obstruction, a condition known as bronchiolitis…”
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Optimizing transplantation of sensitized heart candidates using 4 antibody detection assays to prioritize the assignment of unacceptable antigens by Reinsmoen, Nancy L., PhD, Patel, Jignesh, MD, PhD, Mirocha, James, MS, Lai, Chih-hung, PhD, Naim, Mehrnoush, BS, Ong, Geraldine, BS, Wang, Qi, MS, Zhang, Xiaohai, PhD, Liou, Frank, BS, Yu, Zhe, MD, MPH, Kobashigawa, Jon, MD

“…Background The virtual crossmatch relies on the assignment of unacceptable antigens (UAs) to identify compatible donors. The purpose of our study was to…”
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Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection by Stewart, Susan, Winters, Gayle L, Fishbein, Michael C, Tazelaar, Henry D, Kobashigawa, Jon, Abrams, Jacki, Andersen, Claus B, Angelini, Annalisa, Berry, Gerald J, Burke, Margaret M, Demetris, Anthony J, Hammond, Elizabeth, Itescu, Silviu, Marboe, Charles C, McManus, Bruce, Reed, Elaine F, Reinsmoen, Nancy L, Rodriguez, E Rene, Rose, Alan G, Rose, Marlene, Suciu-Focia, Nicole, Zeevi, Adriana, Billingham, Margaret E

“…In 1990, an international grading system for cardiac allograft biopsies was adopted by the International Society for Heart Transplantation. This system has…”
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Anti-Angiotensin Type 1 Receptor Antibodies Associated With Antibody Mediated Rejection in Donor HLA Antibody Negative Patients by REINSMOEN, Nancy L, LAI, Chih-Hung, VO, Ashley A, JORDAN, Stanley C, DRAGUN, Duska, HEIDECKE, Harald, HAAS, Mark, KAI CAO, ONG, Geraldine, NAIM, Mehrnoush, QI WANG, MIROCHA, James, KAHWAJI, Joseph

“…Angiotensin type 1 receptor (AT1R) mediates most physiologic and pathophysiologic actions of its endogenous ligand, angiotensin II, with overactivity leading…”
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