Search Results - "Reinke, Emily N"
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IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
Published in Toxics (Basel) (01-05-2022)“…During the past few decades, the science of toxicology has been undergoing a transformation from observational to predictive science. New approach…”
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Journal Article -
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Translational regulation of GPx-1 and GPx-4 by the mTOR pathway
Published in PloS one (01-04-2014)“…Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor…”
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Journal Article -
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Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies
Published in Regulatory toxicology and pharmacology (01-04-2018)“…Acute systemic toxicity data are used by a number of U.S. federal agencies, most commonly for hazard classification and labeling and/or risk assessment for…”
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Journal Article -
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Comparative Toxicity of Seven Aqueous Film‐Forming Foam to In Vitro Systems and Mus
Published in Environmental toxicology and chemistry (01-11-2023)“…The comparative toxicity of six per‐ and polyfluoroalkyl substance (PFAS)–free and one PFAS‐containing aqueous film‐forming foam (AFFF) was evaluated in an…”
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Journal Article -
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Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
Published in Toxicology in vitro (01-10-2018)“…New approaches are needed to assess the effects of inhaled substances on human health. These approaches will be based on mechanisms of toxicity, an…”
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Journal Article -
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Skin sensitization testing needs and data uses by US regulatory and research agencies
Published in Archives of toxicology (01-02-2019)“…United States regulatory and research agencies may rely upon skin sensitization test data to assess the sensitization hazards associated with dermal exposure…”
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Journal Article -
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In vitro and in vivo effects of 5-aminotetrazole (5-AT), an energetic compound
Published in Regulatory toxicology and pharmacology (01-03-2020)“…Perchlorate is an important oxidizer used in propellants, pyrotechnics, and as a gas generator in commercial airbags, fireworks, and roadside flares. It is…”
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Journal Article -
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Exposure of chronic myelogenous leukemia cells to imatinib results in the post-transcriptional induction of manganese superoxide dismutase
Published in Leukemia & lymphoma (01-04-2015)“…Abstract The treatment of chronic myelogenous leukemia (CML) with specific tyrosine kinase inhibitors typically results in clinical success, although…”
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Journal Article -
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The Post-Transcriptional Regulation of Antioxidant Enzymes
Published 01-01-2013“…A study was conducted exploring the post-transcriptional regulation of four antioxidant enzymes: glutathione peroxidase 1 (GPx1), manganese superoxide…”
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Dissertation -
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The Post-Transcriptional Regulation of Antioxidant Enzymes
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Dissertation