Search Results - "Reinius, Lovisa E"
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Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility
Published in PloS one (25-07-2012)“…Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be measured by a large number of methods, now even in a genome-wide…”
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2
Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-01-2016)“…Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels. To examine serum…”
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The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma
Published in Journal of allergy and clinical immunology (01-08-2013)“…Background Problematic severe childhood asthma includes a subgroup of patients who are resistant to therapy. The specific mechanisms involved are unknown, and…”
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Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes
Published in Clinical epigenetics (26-03-2015)“…Age-related changes in DNA methylation occurring in blood leukocytes during early childhood may reflect epigenetic maturation. We hypothesized that some of…”
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Differentially methylated regions in maternal and paternal uniparental disomy for chromosome 7
Published in Epigenetics (01-03-2014)“…DNA methylation is a hallmark of genomic imprinting and differentially methylated regions (DMRs) are found near and in imprinted genes. Imprinted genes are…”
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DNA methylation in the Neuropeptide S Receptor 1 (NPSR1) promoter in relation to asthma and environmental factors
Published in PloS one (2013)“…Asthma and allergy are complex disorders influenced by both inheritance and environment, a relationship that might be further clarified by epigenetics…”
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7
Amino Acid Signatures to Evaluate the Beneficial Effects of Weight Loss
Published in International Journal of Endocrinology (01-01-2017)“…Aims. We investigated the relationship between circulating amino acid levels and obesity; to what extent weight loss followed by weight maintenance can correct…”
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Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus
Published in Human molecular genetics (01-02-2015)“…Single-nucleotide polymorphisms (SNPs) in GSDMB (Gasdermin B) and ORMDL3 (ORMDL sphingolipid biosynthesis regulator 3) are strongly associated with childhood…”
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Hypomethylation of HOXA4 promoter is common in Silver-Russell syndrome and growth restriction and associates with stature in healthy children
Published in Scientific reports (16-11-2017)“…Silver-Russell syndrome (SRS) is a growth retardation syndrome in which loss of methylation on chromosome 11p15 (11p15 LOM) and maternal uniparental disomy for…”
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DNA methylation levels within the CD14 promoter region are lower in placentas of mothers living on a farm
Published in Allergy (Copenhagen) (01-07-2012)“…Background Epigenetic regulation has been suggested to be a link between environmental intrauterine exposures and development of asthma and allergy. The…”
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High-resolution targeted bisulfite sequencing reveals blood cell type-specific DNA methylation patterns in IL13 and ORMDL3
Published in Clinical epigenetics (10-05-2021)“…Methylation of DNA at CpG sites is an epigenetic modification and a potential modifier of disease risk, possibly mediating environmental effects. Currently,…”
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DNA methylation levels within the CD 14 promoter region are lower in placentas of mothers living on a farm
Published in Allergy (Copenhagen) (01-07-2012)“…Abstract Background Epigenetic regulation has been suggested to be a link between environmental intrauterine exposures and development of asthma and allergy…”
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13
DNA Methylation in the Neuropeptide S Receptor 1
Published in PloS one (23-01-2013)“…Asthma and allergy are complex disorders influenced by both inheritance and environment, a relationship that might be further clarified by epigenetics…”
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