Search Results - "Reinhart, Todd A"

Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection by Gopal, Radha, Monin, Leticia, Slight, Samantha, Uche, Uzodinma, Blanchard, Emmeline, Fallert Junecko, Beth A, Ramos-Payan, Rosalio, Stallings, Christina L, Reinhart, Todd A, Kolls, Jay K, Kaushal, Deepak, Nagarajan, Uma, Rangel-Moreno, Javier, Khader, Shabaana A

“…Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), infects one third of the world's population. Among these infections, clinical…”
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Induction of CD8+ T-Cell Responses Against Novel Glioma–Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma by OKADA, Hideho, KALINSKI, Pawel, ZEH, Herbert, HOLTZMAN, Matthew P, REINHART, Todd A, WHITESIDE, Theresa L, BUTTERFIELD, Lisa H, HAMILTON, Ronald L, POTTER, Douglas M, POLLACK, Ian F, SALAZAR, Andres M, LIEBERMAN, Frank S, UEDA, Ryo, HOJI, Aki, KOHANBASH, Gary, DONEGAN, Teresa E, MINTZ, Arlan H, ENGH, Johnathan A, BARTLETT, David L, BROWN, Charles K

“…Purpose A phase I/II trial was performed to evaluate the safety and immunogenicity of a novel vaccination with α-type 1 polarized dendritic cells (αDC1) loaded…”
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Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection by Jhingran, Anupam, Kasahara, Shinji, Shepardson, Kelly M, Junecko, Beth A Fallert, Heung, Lena J, Kumasaka, Debra K, Knoblaugh, Sue E, Lin, Xin, Kazmierczak, Barbara I, Reinhart, Todd A, Cramer, Robert A, Hohl, Tobias M

“…Aspergillus fumigatus forms ubiquitous airborne conidia that humans inhale on a daily basis. Although respiratory fungal infection activates the adaptor…”
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IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung by Khader, Shabaana A, Guglani, Lokesh, Rangel-Moreno, Javier, Gopal, Radha, Junecko, Beth A Fallert, Fountain, Jeffrey J, Martino, Cynthia, Pearl, John E, Tighe, Michael, Lin, Yin-yao, Slight, Samantha, Kolls, Jay K, Reinhart, Todd A, Randall, Troy D, Cooper, Andrea M

“…IL-23 is required for the IL-17 response to infection with Mycobacterium tuberculosis, but is not required for the early control of bacterial growth. However,…”
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Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma by Hadebe, Sabelo, Kirstein, Frank, Fierens, Kaat, Chen, Kong, Drummond, Rebecca A, Vautier, Simon, Sajaniemi, Sara, Murray, Graeme, Williams, David L, Redelinghuys, Pierre, Reinhart, Todd A, Fallert Junecko, Beth A, Kolls, Jay K, Lambrecht, Bart N, Brombacher, Frank, Brown, Gordon D

“…Asthma is a heterogeneous disease whose etiology is poorly understood but is likely to involve innate responses to inhaled microbial components that are found…”
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Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates by Koday, Merika T, Leonard, Jolie A, Munson, Paul, Forero, Adriana, Koday, Michael, Bratt, Debra L, Fuller, James T, Murnane, Robert, Qin, Shulin, Reinhart, Todd A, Duus, Karen, Messaoudi, Ilhem, Hartman, Amy L, Stefano-Cole, Kelly, Morrison, Juliet, Katze, Michael G, Fuller, Deborah Heydenburg

“…Recent avian and swine-origin influenza virus outbreaks illustrate the ongoing threat of influenza pandemics. We investigated immunogenicity and protective…”
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TNF-α from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection by Fei, Mingjian, Bhatia, Shikha, Oriss, Timothy B., Yarlagadda, Manohar, Khare, Anupriya, Akira, Shizuo, Saijo, Shinobu, Iwakura, Yoichiro, Junecko, Beth A. Fallert, Reinhart, Todd A., Foreman, Oded, Ray, Prabir, Kolls, Jay, Ray, Anuradha, Beutler, Bruce

“…Aspergillus fumigatus is commonly associated with allergic bronchopulmonary aspergillosis in patients with severe asthma in which chronic airway neutrophilia…”
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A Hydrolase of Trehalose Dimycolate Induces Nutrient Influx and Stress Sensitivity to Balance Intracellular Growth of Mycobacterium tuberculosis by Yang, Yong, Kulka, Kathleen, Montelaro, Ronald C., Reinhart, Todd A., Sissons, James, Aderem, Alan, Ojha, Anil K.

“…Chronic tuberculosis in an immunocompetent host is a consequence of the delicately balanced growth of Mycobacterium tuberculosis (Mtb) in the face of host…”
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Early Events in Mycobacterium tuberculosis Infection in Cynomolgus Macaques by Lin, Philana Ling, Pawar, Santosh, Myers, Amy, Pegu, Amarenda, Fuhrman, Carl, Reinhart, Todd A, Capuano, Saverio V, Klein, Edwin, Flynn, JoAnne L

“…Little is known regarding the early events of infection of humans with Mycobacterium tuberculosis. The cynomolgus macaque is a useful model of tuberculosis,…”
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Human Herpesvirus 8 Infects and Replicates in Primary Cultures of Activated B Lymphocytes through DC-SIGN by RAPPOCCIOLO, Giovanna, HENSLER, Heather R, JAIS, Mariel, REINHART, Todd A, PEGU, Amarendra, JENKINS, Frank J, RINALDO, Charles R

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Lipocalin 2 regulates inflammation during pulmonary mycobacterial infections by Guglani, Lokesh, Gopal, Radha, Rangel-Moreno, Javier, Junecko, Beth Fallert, Lin, Yinyao, Berger, Thorsten, Mak, Tak W, Alcorn, John F, Randall, Troy D, Reinhart, Todd A, Chan, Yvonne R, Khader, Shabaana A

“…Pulmonary tuberculosis (TB), caused by the intracellular bacteria Mycobacterium tuberculosis, is a worldwide disease that continues to kill more than 1.5…”
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Human Lymphatic Endothelial Cells Express Multiple Functional TLRs by Pegu, Amarendra, Qin, Shulin, Fallert Junecko, Beth A, Nisato, Riccardo E, Pepper, Michael S, Reinhart, Todd A

“…The lymphatic endothelium is the preferred route for the drainage of interstitial fluid from tissues and also serves as a conduit for peripheral dendritic…”
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Massive Mobilization of Dendritic Cells During Influenza A Virus Subtype H5N1 Infection of Nonhuman Primates by Soloff, Adam C., Bissel, Stephanie J., Junecko, Beth Fallert, Giles, Brendan M., Reinhart, Todd A., Ross, Ted M., Barratt-Boyes, Simon M.

“…Highly pathogenic avian influenza virus infection is characterized by a marked inflammatory response, but the impact of infection on dendritic cells (DCs) is…”
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Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment by Qin, Shulin, Alcorn, John F, Craigo, Jodi K, Tjoeng, Charis, Tarwater, Patrick M, Kolls, Jay K, Reinhart, Todd A

“…One major activity of chemokines is the recruitment of immune cells to sites of infection and inflammation. CD4(+) Th1 cells play critical roles in host…”
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Purification and Characterization of Mouse Soluble Receptor for Advanced Glycation End Products (sRAGE) by Hanford, Lana E., Enghild, Jan J., Valnickova, Zuzana, Petersen, Steen V., Schaefer, Lisa M., Schaefer, Todd M., Reinhart, Todd A., Oury, Tim D.

“…The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin superfamily of cell surface proteins that has been implicated as a…”
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Neuroinvasion of Fluorescein-Positive Monocytes in Acute Simian Immunodeficiency Virus Infection by CLAY, Candice C, RODRIGUES, Denise S, HO, Yan S, FALLERT, Beth A, JANATPOUR, Kim, REINHART, Todd A, ESSER, Ursula

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miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy by Sasaki, Kotaro, Kohanbash, Gary, Hoji, Aki, Ueda, Ryo, McDonald, Heather A, Reinhart, Todd A, Martinson, Jeremy, Lotze, Michael T, Marincola, Francesco M, Wang, Ena, Fujita, Mitsugu, Okada, Hideho

“…Type-1 T cells are critical for effective anti-tumor immune responses. The recently discovered microRNAs (miRs) are a large family of small regulatory RNAs…”
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DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes by Rappocciolo, Giovanna, Piazza, Paolo, Fuller, Craig L, Reinhart, Todd A, Watkins, Simon C, Rowe, David T, Jais, Mariel, Gupta, Phalguni, Rinaldo, Charles R

“…Infection of T cells by HIV-1 can occur through binding of virus to dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (DC-SIGN) on dendritic cells and…”
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Increased Expression of TLR3 in Lymph Nodes during Simian Immunodeficiency Virus Infection: Implications for Inflammation and Immunodeficiency by Sanghavi, Sonali K, Reinhart, Todd A

“…As pattern recognition receptors, TLRs signal and induce expression of multiple host defense genes including proinflammatory cytokines and chemokines. To…”
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Correction: Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma by Hadebe, Sabelo, Kirstein, Frank, Fierens, Kaat, Chen, Kong, Drummond, Rebecca A, Vautier, Simon, Sajaniemi, Sara, Murray, Graeme, Williams, David L, Redelinghuys, Pierre, Reinhart, Todd A, Junecko, Beth A Fallert, Kolls, Jay K, Lambrecht, Bart N, Brombacher, Frank, Brown, Gordon D

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