Search Results - "Reiner, P. B."

Regulation of Amyloid Precursor Protein Cleavage by Mills, Julia, Reiner, Peter B.

“…: Multiple lines of evidence suggest that increased production and/or deposition of the β‐amyloid peptide, derived from the amyloid precursor protein,…”
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Dynamic properties of corticothalamic excitatory postsynaptic potentials and thalamic reticular inhibitory postsynaptic potentials in thalamocortical neurons of the guinea-pig dorsal lateral geniculate nucleus by von Krosigk, M., Monckton, J.E., Reiner, P.B., McCormick, D.A.

“…The properties of postsynaptic potentials evoked by stimulation of cortical, retinal and GABAergic thalamic afferents were examined in vitro in thalamocortical…”
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Serotonin Hyperpolarizes Cholinergic Low-Threshold Burst Neurons in the Rat Laterodorsal Tegmental Nucleus in vitro by Luebke, J. I., Greene, R. W., Semba, K., Kamondi, A., McCarley, R. W., Reiner, P. B.

“…Serotonergic suppression of cholinergic neuronal activity implicated in the regulation of rapid eye movement sleep and its associated phenomenon,…”
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Noradrenaline hyperpolarizes identified rat mesopontine cholinergic neurons in vitro by Williams, JA, Reiner, PB

“…Inhibition of brainstem cholinergic neurons by noradrenergic neurons of the locus ceruleus has long been suggested as a key mechanism of behavioral state…”
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Histamine depolarizes cholinergic septal neurons by Gorelova, N, Reiner, P B

“…1. Bath application of 10 microM histamine (HA) resulted in a depolarization or inward current in 58/59 cholinergic neurons located in the medial septum and…”
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Role of the afterhyperpolarization in control of discharge properties of septal cholinergic neurons in vitro by Gorelova, N, Reiner, P B

“…1. The properties of the cholinergic neurons of the rat medial septum and nucleus of the diagonal band of Broca (MS/DBB) were studied using whole cell…”
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Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current by Reiner, P B, Kamondi, A

“…Antihistamines, more formally termed H1 receptor antagonists, are well known to exert sedative effects in humans, yet their locus and mechanism of action in…”
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Mitogen-activated protein kinase is involved in N-methyl- d-aspartate receptor regulation of amyloid precursor protein cleavage by Mills, J, Reiner, P.B

“…Glutamate is the principal excitatory neurotransmitter in the mammalian brain. Several lines of evidence suggest that glutamatergic hypoactivity exists in the…”
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Noradrenaline excites non-cholinergic laterodorsal tegmental neurons via two distinct mechanisms by Kohlmeier, K.A., Reiner, P.B.

“…Cholinergic neurons of the laterodorsal tegmental nucleus have been hypothesized to play a critical role in the generation and maintenance of rapid eye…”
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State-dependent release of acetylcholine in rat thalamus measured by in vivo microdialysis by Williams, JA, Comisarow, J, Day, J, Fibiger, HC, Reiner, PB

“…Mesopontine cholinergic neurons have long been thought to play a key role in behavioral state control. In particular, they have been implicated in the process…”
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Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat by Semba, K, Reiner, P B, Fibiger, H C

“…Microinjections of the cholinergic agonist carbachol into a caudal part of the pontine reticular formation of the rat induce a rapid eye movement sleep-like…”
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Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat by Semba, K, Reiner, P B, McGeer, E G, Fibiger, H C

“…Brainstem afferents to the magnocellular basal forebrain were studied by using tract tracing, immunohistochemistry and extracellular recordings in the rat…”
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Membrane properties of mesopontine cholinergic neurons studied with the whole-cell patch-clamp technique: implications for behavioral state control by Kamondi, A, Williams, J A, Hutcheon, B, Reiner, P B

“…1. The whole-cell patch-clamp technique was used to study the membrane properties of identified cholinergic and noncholinergic laterodorsal tegmental neurons…”
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Hyperpolarization-activated inward current in histaminergic tuberomammillary neurons of the rat hypothalamus by Kamondi, A, Reiner, P B

“…1. Intracellular recordings were obtained from histaminergic tuberomammillary (TM) neurons of rat hypothalamus in an in vitro slice preparation. The properties…”
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Membrane properties of histaminergic tuberomammillary neurones of the rat hypothalamus in vitro by Haas, H L, Reiner, P B

“…1. Intracellular recordings were obtained from neurones of the tuberomammillary nucleus in an in vitro explant of the rat hypothalamus. 2. Tuberomammillary…”
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Localization of the cGMP-dependent protein kinases in relation to nitric oxide synthase in the brain by El-Husseini, A.E.-D, Williams, J, Reiner, P.B, Pelech, S, Vincent, S.R

“…The distributions of the type I and type II isoforms of cGMP-dependent protein kinase were determined in the rat brain using immunohistochemistry and in situ…”
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β‐Amyloid efflux mediated by p‐glycoprotein by Lam, Fred C., Liu, Ronghua, Lu, Peihua, Shapiro, Adam B., Renoir, Jack‐Michel, Sharom, Frances J., Reiner, Peter B.

“…A large body of evidence suggests that an increase in the brain β‐amyloid (Aβ) burden contributes to the etiology of Alzheimer's disease (AD). Much is now…”
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Reduced ionic conductance in turtle brain by Doll, C J, Hochachka, P W, Reiner, P B

“…Whole cell recording techniques were employed to measure whole cell (Gw) and specific membrane (Gm) conductance in turtle and rat pyramidal neurons in slices…”
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Effects of anoxia and metabolic arrest on turtle and rat cortical neurons by Doll, C J, Hochachka, P W, Reiner, P B

“…The responses of turtle and rat cortical pyramidal neurons to various pharmacological treatments were measured using intracellular recordings. Turtle neurons…”
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Novel Effects of FCCP [Carbonyl Cyanide p‐(Trifluoromethoxy)phenylhydrazone] on Amyloid Precursor Protein Processing by Connop, Bruce P., Thies, Robert L., Beyreuther, Konrad, Ida, Nobuo, Reiner, Peter B.

“…: Amyloidogenic processing of the β‐amyloid precursor protein (APP) has been implicated in the pathology of Alzheimer’s disease. Because it has been suggested…”
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