Search Results - "Reiner, Martin F."
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Amotosalen/ultraviolet A pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance
Published in Haematologica (Roma) (01-10-2017)“…Amotosalen and ultraviolet A (UVA) photochemical-based pathogen reduction using the Intercept™ Blood System (IBS) is an effective and established technology…”
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Effects of acute administration of trimethylamine N-oxide on endothelial function: a translational study
Published in Scientific reports (23-05-2022)“…Elevated circulating levels of nutrient-derived trimethylamine N-oxide (TMAO) have been associated with the onset and progression of cardiovascular disease by…”
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Prevention of M2 polarization and temporal limitation of differentiation in monocytes by extracellular ATP
Published in BMC immunology (23-06-2023)“…Elevated levels of extracellular adenosine triphosphate (ATP) modulate immunologic pathways and are considered to be a danger signal in inflammation, lung…”
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Prevalence and risk of inappropriate dosing of direct oral anticoagulants in two Swiss atrial fibrillation registries
Published in Vascular pharmacology (01-12-2022)“…Direct oral anticoagulants (DOACs) have a favourable risk-benefit profile compared to vitamin K-antagonists (VKAs) in atrial fibrillation (AF). Dosing is based…”
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Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation
Published in Nutrients (01-01-2024)“…Omega-3 fatty acids ( -3 FAs) are associated with a lower risk of ischemic stroke in patients with atrial fibrillation (AF). Antithrombotic mechanisms may in…”
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Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways
Published in Cardiovascular research (01-04-2017)“…The lectin-like oxLDL receptor-1 (LOX-1) promotes endothelial uptake of oxidized low-density lipoprotein (oxLDL) and plays an important role in atherosclerosis…”
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Omega-3 Fatty Acids and Heart Rhythm, Rate, and Variability in Atrial Fibrillation
Published in Journal of the American Heart Association (06-06-2023)“…Background Previous randomized control trials showed mixed results concerning the effect of omega-3 fatty acids (n-3 FAs) on atrial fibrillation (AF). The…”
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The Omega-3 Fatty Acid Eicosapentaenoic Acid (EPA) Correlates Inversely with Ischemic Brain Infarcts in Patients with Atrial Fibrillation
Published in Nutrients (01-02-2021)“…The omega-3 fatty acid (n-3 FA) eicosapentaenoic acid (EPA) reduces stroke in patients with atherosclerotic cardiovascular disease. Whether EPA affects stroke…”
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Blood Omega-3 Fatty Acids Are Inversely Associated With Albumin-Creatinine Ratio in Young and Healthy Adults (The Omega-Kid Study)
Published in Frontiers in cardiovascular medicine (27-04-2021)“…Omega-3 fatty acids are associated with a lower risk of cardiovascular disease (CVD) and with beneficial effects on CV risk factors. The albumin-creatinine…”
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AP-1 (Activated Protein-1) Transcription Factor JunD Regulates Ischemia/Reperfusion Brain Damage via IL-1β (Interleukin-1β)
Published in Stroke (1970) (01-02-2019)“…BACKGROUND AND PURPOSE—Inflammation is a major pathogenic component of ischemia/reperfusion brain injury, and as such, interventions aimed at inhibiting…”
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Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity
Published in Cardiovascular research (01-07-2018)“…Abstract Aims Sirtuin 3 (Sirt3) is a mitochondrial, nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase that reduces oxidative stress by activation…”
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Acute kidney injury associated with COVID-19: a prognostic factor for pulmonary embolism or co-incidence?
Published in European heart journal (21-12-2020)Get full text
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Whole blood omega-3 fatty acid concentrations are inversely associated with blood pressure in young, healthy adults
Published in Journal of hypertension (01-07-2018)“…BACKGROUND:Omega-3 fatty acids (n − 3 FA) may have blood pressure (BP)-lowering effects in untreated hypertensive and elderly patients. The effect of n − 3 FA…”
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Gut microbiota-dependent trimethylamine-N-oxide (TMAO) shows a U-shaped association with mortality but not with recurrent venous thromboembolism
Published in Thrombosis research (01-02-2019)“…Gut microbiota-dependent trimethylamine-N-oxide (TMAO) correlates with arterial thrombotic events including myocardial infarction and stroke, and mortality…”
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Reduction of albumin urinary excretion is associated with reduced cardiovascular events in hypertensive and/or diabetic patients. A meta-regression analysis of 32 randomized trials
Published in International journal of cardiology (15-03-2014)“…Abstract Background The association between renal dysfunction and risk of cardiovascular (CV) events and mortality has been reported in several studies…”
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Case report of long-term postural tachycardia syndrome in a patient after messenger RNA coronavirus disease-19 vaccination with mRNA-1273
Published in European heart journal : case reports (01-08-2023)“…Abstract Background Postural tachycardia syndrome (POTS) is characterized by orthostatic intolerance and heart rate increase in an upright position without…”
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Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury
Published in Journal of cerebral blood flow and metabolism (01-11-2019)“…Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is implicated in cardiovascular disease by modulating apoptosis and oxidative stress. We…”
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Elevated HbA1c is not associated with recurrent venous thromboembolism in the elderly, but with all-cause mortality– the SWEETCO 65+ study
Published in Scientific reports (12-02-2020)“…The association of glycated hemoglobin (HbA1c) with venous thromboembolism (VTE) and death in the elderly is unknown. In the SWEETCO 65+ study we analyzed…”
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Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression
Published in Cardiovascular research (01-01-2017)“…The P2Y antagonist ticagrelor reduces mortality in patients with acute coronary syndrome (ACS), compared with clopidogrel, and the mechanisms underlying this…”
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