Search Results - "Reiner, E"

Disease Detection and Management via Single Nanopore-Based Sensors by Reiner, Joseph E, Balijepalli, Arvind, Robertson, Joseph W. F, Campbell, Jason, Suehle, John, Kasianowicz, John J

“…Reiner et al provide a biochemical analysis of single nanopore-based sensors and their role in disease detection and management. Solid-state nanopore-based…”
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Optical tweezers as an effective tool for spermatozoa isolation from mixed forensic samples by Auka, Nicole, Valle, Michael, Cox, Bobby D, Wilkerson, Peter D, Dawson Cruz, Tracey, Reiner, Joseph E, Seashols-Williams, Sarah J

“…A single focus optical tweezer is formed when a laser beam is launched through a high numerical aperture immersion objective. This objective focuses the beam…”
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Legacy and new halogenated persistent organic pollutants in polar bears from a contamination hotspot in the Arctic, Hudson Bay Canada by Letcher, R.J., Morris, A.D., Dyck, M., Sverko, E., Reiner, E.J., Blair, D.A.D., Chu, S.G., Shen, L.

“…A large and complex suite of 295 legacy and new halogenated persistent organic pollutants (POPs) were investigated in fat or liver tissue samples of polar…”
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Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging by Lambertz, Ulrike, Oviedo Ovando, Mariana E, Vasconcelos, Elton J R, Unrau, Peter J, Myler, Peter J, Reiner, Neil E

“…Leishmania use exosomes to communicate with their mammalian hosts and these secreted vesicles appear to contribute to pathogenesis by delivering protein…”
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Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells by Silverman, Judith Maxwell, Clos, Joachim, Horakova, Eva, Wang, Adele Y, Wiesgigl, Martina, Kelly, Isabelle, Lynn, Miriam A, McMaster, W Robert, Foster, Leonard J, Levings, Megan K, Reiner, Neil E

“…We investigated the properties of leishmania exosomes with respect to influencing innate and adaptive immune responses. Exosomes from Leishmania donovani…”
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Theory for polymer analysis using nanopore-based single-molecule mass spectrometry by Reiner, Joseph E., Kasianowicz, John J., Nablo, Brian J., Robertson, Joseph W. F., Turro, Nichloas J.

“…Nanometer-scale pores have demonstrated potential for the electrical detection, quantification, and characterization of molecules for biomedical applications…”
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Secreted virulence factors and immune evasion in visceral leishmaniasis by Lambertz, Ulrike, Silverman, Judith Maxwell, Nandan, Devki, McMaster, W. Robert, Clos, Joachim, Foster, Leonard J., Reiner, Neil E.

“…Review of leishmania secreted virulence factors and their immune‐modulatory functions, as well as exosome release as a major mechanism for effector secretion…”
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Sleeping with the enemy: how intracellular pathogens cope with a macrophage lifestyle by Thi, Emily P, Lambertz, Ulrike, Reiner, Neil E

“…Targeting Critical Signaling Pathways Prevents Effective Macrophage Activation and Promotes Survival of Intracellular Pathogens Activated macrophages form a…”
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Miransertib (ARQ 092), an orally-available, selective Akt inhibitor is effective against Leishmania by Nandan, Devki, Zhang, Naixin, Yu, Yi, Schwartz, Brian, Chen, Stella, Kima, Peter E, Reiner, Neil E

“…Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally…”
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Frequency and Complexity of De Novo Structural Mutation in Autism by Brandler, William M., Antaki, Danny, Gujral, Madhusudan, Noor, Amina, Rosanio, Gabriel, Chapman, Timothy R., Barrera, Daniel J., Lin, Guan Ning, Malhotra, Dheeraj, Watts, Amanda C., Wong, Lawrence C., Estabillo, Jasper A., Gadomski, Therese E., Hong, Oanh, Fajardo, Karin V. Fuentes, Bhandari, Abhishek, Owen, Renius, Baughn, Michael, Yuan, Jeffrey, Solomon, Terry, Moyzis, Alexandra G., Maile, Michelle S., Sanders, Stephan J., Reiner, Gail E., Vaux, Keith K., Strom, Charles M., Zhang, Kang, Muotri, Alysson R., Akshoomoff, Natacha, Leal, Suzanne M., Pierce, Karen, Courchesne, Eric, Iakoucheva, Lilia M., Corsello, Christina, Sebat, Jonathan

“…Genetic studies of autism spectrum disorder (ASD) have established that de novo duplications and deletions contribute to risk. However, ascertainment of…”
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Proteomic analysis of the secretome of Leishmania donovani by Silverman, J Maxwell, Chan, Simon K, Robinson, Dale P, Dwyer, Dennis M, Nandan, Devki, Foster, Leonard J, Reiner, Neil E

“…Leishmania and other intracellular pathogens have evolved strategies that support invasion and persistence within host target cells. In some cases the…”
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Dechlorane-Related Compounds in Franciscana Dolphin (Pontoporia blainvillei) from Southeastern and Southern Coast of Brazil by de la Torre, A, Alonso, M. B, Martínez, M. A, Sanz, P, Shen, L, Reiner, E. J, Lailson-Brito, J, Torres, J. P. M, Bertozzi, C, Marigo, J, Barbosa, L, Cremer, M, Secchi, E, Malm, O, Eljarrat, E, Barceló, D

“…Concentrations of Dechlorane (Dec) 603 (0.75 ng/g lipid weight (lw); mean) and Dec 602 (0.38 ng/g lw; mean) were quantified in more than 95% of the franciscana…”
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Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles by Martínez-Gutierrez, Fidel, MSc, Thi, Emily P., BSc, Silverman, Judith M., PhD, de Oliveira, Carolina Camargo, PhD, Svensson, Sarah L., BSc, Hoek, Amanda Vanden, BSc, Sánchez, Elpidio Morales, PhD, Reiner, Neil E., MD, Gaynor, Erin C., PhD, Pryzdial, Edward L.G., PhD, Conway, Edward M., MD, PhD, Orrantia, Erasmo, PhD, Ruiz, Facundo, PhD, Av-Gay, Yossef, PhD, Bach, Horacio, PhD

“…Abstract The incorporation of nanoparticles (NPs) in industrial and biomedical applications has increased significantly in recent years, yet their hazardous…”
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Preparation of nanoparticles by continuous-flow microfluidics by Jahn, Andreas, Reiner, Joseph E., Vreeland, Wyatt N., DeVoe, Don L., Locascio, Laurie E., Gaitan, Michael

“…We review a variety of micro- and nanoparticle formulations produced with microfluidic methods. A diverse variety of approaches to generate microscale and…”
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Phosphatidylinositol 3-kinases and their roles in phagosome maturation by Thi, Emily P., Reiner, Neil E.

“…Review on how PI3Ks regulate phagosome maturation downstream of different phagocytic receptors, and their involvement in Rab activation and Ca2+ signaling…”
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Nanoscopic porous sensors by Kasianowicz, John J, Robertson, Joseph W F, Chan, Elaine R, Reiner, Joseph E, Stanford, Vincent M

“…There are thousands of different nanometer-scale pores in biology, many of which act as sensors for specific chemical agents. Recent work suggests that protein…”
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Congener specific determination of polychlorinated naphthalenes in sediment and biota by gas chromatography high resolution mass spectrometry by Lega, R., Megson, D., Hartley, C., Crozier, P., MacPherson, K., Kolic, T., Helm, P.A., Myers, A., Bhavsar, S.P., Reiner, E.J.

“…•Congener specific analysis of 24 most toxic and abundant PCNs in sediment and biota.•Femtogram IDLs and low to sub pg/g MDLs in sediment and biota.•Average…”
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Survival of Mycobacterium tuberculosis in Host Macrophages Involves Resistance to Apoptosis Dependent upon Induction of Antiapoptotic Bcl-2 Family Member Mcl-1 by Sly, Laura M, Hingley-Wilson, Suzanne M, Reiner, Neil E, McMaster, W. Robert

“…Mcl-1 protein expression was found to be up-regulated during infection with virulent Mycobacterium tuberculosis strain H37Rv. Mcl-1 induction in THP-1 cells…”
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Low‐dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial by Naviaux, Robert K., Curtis, Brooke, Li, Kefeng, Naviaux, Jane C., Bright, A. Taylor, Reiner, Gail E., Westerfield, Marissa, Goh, Suzanne, Alaynick, William A., Wang, Lin, Capparelli, Edmund V., Adams, Cynthia, Sun, Ji, Jain, Sonia, He, Feng, Arellano, Deyna A., Mash, Lisa E., Chukoskie, Leanne, Lincoln, Alan, Townsend, Jeanne

“…Objective No drug is yet approved to treat the core symptoms of autism spectrum disorder (ASD). Low‐dose suramin was effective in the maternal immune…”
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The 19-kDa Mycobacterium tuberculosis Protein Induces Macrophage Apoptosis Through Toll-Like Receptor-2 by Lopez, Martin, Sly, Laura M, Luu, Yvonne, Young, Douglas, Cooper, Howard, Reiner, Neil E

“…Macrophages infected with Mycobacterium tuberculosis undergo increased rates of apoptosis. Important objectives are to define the microbial factors that cause…”
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