Search Results - "Reindl, Markus"

Blood–Brain Barrier Breakdown in Neuroinflammation: Current In Vitro Models by Brandl, Sarah, Reindl, Markus

“…The blood–brain barrier, which is formed by tightly interconnected microvascular endothelial cells, separates the brain from the peripheral circulation…”
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A clinical approach to diagnosis of autoimmune encephalitis by Graus, Francesc, Prof, Titulaer, Maarten J, MD, Balu, Ramani, MD, Benseler, Susanne, MD, Bien, Christian G, Prof, Cellucci, Tania, MD, Cortese, Irene, MD, Dale, Russell C, Prof, Gelfand, Jeffrey M, MD, Geschwind, Michael, MD, Glaser, Carol A, MD, Honnorat, Jerome, Prof, Höftberger, Romana, MD, Iizuka, Takahiro, MD, Irani, Sarosh R, MD, Lancaster, Eric, MD, Leypoldt, Frank, MD, Prüss, Harald, MD, Rae-Grant, Alexander, MD, Reindl, Markus, Prof, Rosenfeld, Myrna R, Prof, Rostásy, Kevin, MD, Saiz, Albert, MD, Venkatesan, Arun, MD, Vincent, Angela, Prof, Wandinger, Klaus-Peter, Prof, Waters, Patrick, PhD, Dalmau, Josep, Prof

“…Summary Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune…”
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Recent developments in MOG-IgG associated neurological disorders by Hegen, Harald, Reindl, Markus

“…In the past few years, acquired demyelinating syndromes of the central nervous system associated with antibodies against myelin oligodendrocyte glycoprotein…”
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The spectrum of MOG autoantibody-associated demyelinating diseases by Reindl, Markus, Di Pauli, Franziska, Rostásy, Kevin, Berger, Thomas

“…In this Review, Reindl et al . discuss a range of CNS disorders that are known to be associated with autoantibodies against myelin oligodendrocyte glycoprotein…”
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Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases by Peschl, Patrick, Bradl, Monika, Höftberger, Romana, Berger, Thomas, Reindl, Markus

“…Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig) superfamily, is a myelin protein solely expressed at the outermost surface of…”
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Mechanisms for lesion localization in neuromyelitis optica spectrum disorders by Bradl, Monika, Reindl, Markus, Lassmann, Hans

“…Neuromyelitis optica spectrum disorders (NMOSD) are severe inflammatory diseases of the central nervous system (CNS), with the presence of aquaporin 4…”
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Tocilizumab treatment in severe recurrent anti-MOG-associated optic neuritis by Hayward-Koennecke, Helen, Reindl, Markus, Martin, Roland, Schippling, Sven

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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome by Jarius, Sven, Ruprecht, Klemens, Kleiter, Ingo, Borisow, Nadja, Asgari, Nasrin, Pitarokoili, Kalliopi, Pache, Florence, Stich, Oliver, Beume, Lena-Alexandra, Hümmert, Martin W, Ringelstein, Marius, Trebst, Corinna, Winkelmann, Alexander, Schwarz, Alexander, Buttmann, Mathias, Zimmermann, Hanna, Kuchling, Joseph, Franciotta, Diego, Capobianco, Marco, Siebert, Eberhard, Lukas, Carsten, Korporal-Kuhnke, Mirjam, Haas, Jürgen, Fechner, Kai, Brandt, Alexander U, Schanda, Kathrin, Aktas, Orhan, Paul, Friedemann, Reindl, Markus, Wildemann, Brigitte

“…A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies…”
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Overlapping demyelinating syndromes and anti-N-methyl-D-aspartate receptor encephalitis by Titulaer, Maarten J., Höftberger, Romana, Iizuka, Takahiro, Leypoldt, Frank, McCracken, Lindsey, Cellucci, Tania, Benson, Leslie A., Shu, Huidy, Irioka, Takashi, Hirano, Makito, Singh, Gagandeep, Cobo Calvo, Alvaro, Kaida, Kenichi, Morales, Pamela S., Wirtz, Paul W., Yamamoto, Tomotaka, Reindl, Markus, Rosenfeld, Myrna R., Graus, Francesc, Saiz, Albert, Dalmau, Josep

“…Objective To report the clinical, radiological, and immunological association of demyelinating disorders with anti–N‐methyl‐D‐aspartate receptor (NMDAR)…”
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Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders by Mader, Simone, Gredler, Viktoria, Schanda, Kathrin, Rostasy, Kevin, Dujmovic, Irena, Pfaller, Kristian, Lutterotti, Andreas, Jarius, Sven, Di Pauli, Franziska, Kuenz, Bettina, Ehling, Rainer, Hegen, Harald, Deisenhammer, Florian, Aboul-Enein, Fahmy, Storch, Maria K, Koson, Peter, Drulovic, Jelena, Kristoferitsch, Wolfgang, Berger, Thomas, Reindl, Markus

“…Serum autoantibodies against the water channel aquaporin-4 (AQP4) are important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO)…”
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Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat by Hillebrand, Sophie, Schanda, Kathrin, Nigritinou, Magdalini, Tsymala, Irina, Böhm, Denise, Peschl, Patrick, Takai, Yoshiki, Fujihara, Kazuo, Nakashima, Ichiro, Misu, Tatsuro, Reindl, Markus, Lassmann, Hans, Bradl, Monika

“…It is well established that the binding of pathogenic aquaporin-4 (AQP4)-specific autoantibodies to astrocytes may initiate a cascade of events culminating in…”
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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients by Pache, Florence, Zimmermann, Hanna, Mikolajczak, Janine, Schumacher, Sophie, Lacheta, Anna, Oertel, Frederike C, Bellmann-Strobl, Judith, Jarius, Sven, Wildemann, Brigitte, Reindl, Markus, Waldman, Amy, Soelberg, Kerstin, Asgari, Nasrin, Ringelstein, Marius, Aktas, Orhan, Gross, Nikolai, Buttmann, Mathias, Ach, Thomas, Ruprecht, Klemens, Paul, Friedemann, Brandt, Alexander U

“…Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with aquaporin-4 antibody (AQP4-IgG)-negative neuromyelitis…”
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Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo by Bradl, Monika, Misu, Tatsuro, Takahashi, Toshiyuki, Watanabe, Mitsutoshi, Mader, Simone, Reindl, Markus, Adzemovic, Milena, Bauer, Jan, Berger, Thomas, Fujihara, Kazuo, Itoyama, Yasuto, Lassmann, Hans

“…Objective Severe inflammation and astrocyte loss with profound demyelination in spinal cord and optic nerves are typical pathological features of neuromyelitis…”
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MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome by Jarius, Sven, Kleiter, Ingo, Ruprecht, Klemens, Asgari, Nasrin, Pitarokoili, Kalliopi, Borisow, Nadja, Hümmert, Martin W, Trebst, Corinna, Pache, Florence, Winkelmann, Alexander, Beume, Lena-Alexandra, Ringelstein, Marius, Stich, Oliver, Aktas, Orhan, Korporal-Kuhnke, Mirjam, Schwarz, Alexander, Lukas, Carsten, Haas, Jürgen, Fechner, Kai, Buttmann, Mathias, Bellmann-Strobl, Judith, Zimmermann, Hanna, Brandt, Alexander U, Franciotta, Diego, Schanda, Kathrin, Paul, Friedemann, Reindl, Markus, Wildemann, Brigitte

“…Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (ON) and/or…”
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Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease by Flach, Anne-Christine, Litke, Tanja, Strauss, Judith, Haberl, Michael, Gómez, César Cordero, Reindl, Markus, Saiz, Albert, Fehling, Hans-Jörg, Wienands, Jürgen, Odoardi, Francesca, Lühder, Fred, Flügel, Alexander

“…Multiple sclerosis (MS) is caused by T cells that are reactive for brain antigens. In experimental autoimmune encephalomyelitis, the animal model for MS,…”
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Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients by Jarius, Sven, Pellkofer, Hannah, Siebert, Nadja, Korporal-Kuhnke, Mirjam, Hümmert, Martin W, Ringelstein, Marius, Rommer, Paulus S, Ayzenberg, Ilya, Ruprecht, Klemens, Klotz, Luisa, Asgari, Nasrin, Zrzavy, Tobias, Höftberger, Romana, Tobia, Rafik, Buttmann, Mathias, Fechner, Kai, Schanda, Kathrin, Weber, Martin, Asseyer, Susanna, Haas, Jürgen, Lechner, Christian, Kleiter, Ingo, Aktas, Orhan, Trebst, Corinna, Rostasy, Kevin, Reindl, Markus, Kümpfel, Tania, Paul, Friedemann, Wildemann, Brigitte

“…New-generation cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprotein…”
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Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination by Peschl, Patrick, Schanda, Kathrin, Zeka, Bleranda, Given, Katherine, Böhm, Denise, Ruprecht, Klemens, Saiz, Albert, Lutterotti, Andreas, Rostásy, Kevin, Höftberger, Romana, Berger, Thomas, Macklin, Wendy, Lassmann, Hans, Bradl, Monika, Bennett, Jeffrey L, Reindl, Markus

“…Antibodies to the myelin oligodendrocyte glycoprotein (MOG) are associated with a subset of inflammatory demyelinating diseases of the central nervous system…”
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Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study by Bsteh, Gabriel, Ehling, Rainer, Lutterotti, Andreas, Hegen, Harald, Di Pauli, Franziska, Auer, Michael, Deisenhammer, Florian, Reindl, Markus, Berger, Thomas

“…Multiple sclerosis (MS) has a highly heterogenic course making prediction of long term outcome very difficult. The objective was to evaluate current and…”
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Clinical spectrum and IgG subclass analysis of anti-myelin oligodendrocyte glycoprotein antibody-associated syndromes: a multicenter study by Mariotto, Sara, Ferrari, Sergio, Monaco, Salvatore, Benedetti, Maria Donata, Schanda, Kathrin, Alberti, Daniela, Farinazzo, Alessia, Capra, Ruggero, Mancinelli, Chiara, De Rossi, Nicola, Bombardi, Roberto, Zuliani, Luigi, Zoccarato, Marco, Tanel, Raffaella, Bonora, Adriana, Turatti, Marco, Calabrese, Massimiliano, Polo, Alberto, Pavone, Antonino, Grazian, Luisa, Sechi, GianPietro, Sechi, Elia, Urso, Daniele, Delogu, Rachele, Janes, Francesco, Deotto, Luciano, Cadaldini, Morena, Bianchi, Maria Rachele, Cantalupo, Gaetano, Reindl, Markus, Gajofatto, Alberto

“…Anti-myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) recently emerged as a potential biomarker in patients with inflammatory demyelinating diseases of…”
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Peripheral inflammatory response in people after acute ischaemic stroke and isolated spontaneous cervical artery dissection by Bauer, Angelika, Boehme, Christian, Mayer-Suess, Lukas, Rudzki, Dagmar, Knoflach, Michael, Kiechl, Stefan, Reindl, Markus

“…The systemic inflammatory response following acute ischaemic stroke remains incompletely understood. We characterised the circulating inflammatory profile in…”
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