Search Results - "Reinders, Judith"

Dendritic cell migration assay: A potential prediction model for identification of contact allergens by Gibbs, Susan, Spiekstra, Sander, Corsini, Emanuela, McLeod, Julie, Reinders, Judith

“…► Methodology for in vitro DC migration assay for identification of contact allergens. ► Assay limitations, critical points and optimization is described. ►…”
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A potential in vitro epidermal equivalent assay to determine sensitizer potency by dos Santos, Guilherme G., Spiekstra, Sander W., Sampat-Sardjoepersad, Shakun C., Reinders, Judith, Scheper, Rik J., Gibbs, Susan

“…Most in vitro assays aim to distinguish sensitizers from non-sensitizers. Few aim to classify sensitizers according to potency. Here, we describe a potential…”
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Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans cells by Ouwehand, Krista, Spiekstra, Sander W., Reinders, Judith, Scheper, Rik J., de Gruijl, Tanja D., Gibbs, Susan

“…As the induction of contact hypersensitivity is the result of a series of cellular processes, including maturation and migration of epidermal dendritic cells…”
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Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency by Teunis, Marc, Corsini, Emanuela, Smits, Mieke, Madsen, Charlotte Bernhard, Eltze, Tobias, Ezendam, Janine, Galbiati, Valentina, Gremmer, Eric, Krul, Cyrille, Landin, Annette, Landsiedel, Robert, Pieters, Raymond, Rasmussen, Tina Frid, Reinders, Judith, Roggen, Erwin, Spiekstra, Sander, Gibbs, Susan

“…► This study shows the successful transferability of an in vitro sensitization assay. ► The standard operating procedures are discussed at length, so that…”
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An international pre-validation study on the Epidermal Equivalent sensitizer potency assay by Teunis, Marc A.T., Spiekstra, Sander, Smits, Mieke, Adriaens, Els, Eltze, Tobias, Galbiati, Valentina, Krul, Cyrille, Landsiedel, Robert, Pieters, Raymond, Reinders, Judith, Roggen, Erwin, Corsini, Emanuela, Gibbs, Susan

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International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive-capacity by Teunis, Marc A T, Spiekstra, Sander W, Smits, Mieke, Adriaens, Els, Eltze, Tobias, Galbiati, Valentina, Krul, Cyrille, Landsiedel, Robert, Pieters, Raymond, Reinders, Judith, Roggen, Erwin, Corsini, Emanuela, Gibbs, Susan

“…This study describes the international ring trial of the epidermal-equivalent (EE) sensitizer potency assay. This assay does not distinguish a sensitizer from…”
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HLA and MICA associations with head and neck squamous cell carcinoma by Reinders, Judith, Rozemuller, Erik H, Otten, Henny G, van der Veken, Lars T.J.N, Slootweg, Pieter J, Tilanus, Marcel G.J

“…Summary Head and neck squamous cell carcinoma (HNSCC) is a very aggressive tumour arising from the epithelial lining of the upper aerodigestive tract. The…”
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Genes in the HLA region indicative for head and neck squamous cell carcinoma by Reinders, Judith, Rozemuller, Erik H., van der Weide, Petra, Oka, Akira, Slootweg, Pieter J., Inoko, Hidetoshi, Tilanus, Marcel G.J.

“…The majority of genes in the HLA region are directly or indirectly involved in immunological functions. They comprise HLA, HLA-related and non-HLA-related…”
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MHC Class I Chain-Related Gene A Diversity in Head and Neck Squamous Cell Carcinoma by Reinders, Judith, Rozemuller, Erik H., van der Ven, Kevin J.W., Caillat-Zucman, Sophie, Slootweg, Pieter J., de Weger, Roel A., Tilanus, Marcel G.J.

“…Many immune-related genes are located within the human leukocyte antigen (HLA) region on chromosome 6. The MHC class I chain-related gene A (MICA), located…”
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Identification of HLA-A0111N: A Synonymous Substitution, Introducing an Alternative Splice Site in Exon 3, Silenced the Expression of an HLA-A Allele by Reinders, Judith, Rozemuller, Erik H., Otten, Henny G., Houben, Anna J.S., Dormoy, Anne, Mulder, Arend, van den Tweel, Jan G., Petersen, Eefke J., Tilanus, Marcel G.J.

“…A new variant of the HLA-A*010101 allele designated as HLA-A*0111N, previously known as HLA-A*010101var, was identified in a patient requiring a stem-cell…”
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Primary sclerosing cholangitis in two brothers: report of a family with special emphasis on molecular HLA and MICA genotyping by Van Steenbergen, Werner, De Goede, Eric, Emonds, Marie-Paule, Reinders, Judith, Tilanus, Marcel, Fevery, Johan

“…Immune mechanisms play a role in the pathogenesis of primary sclerosing cholangitis (PSC), as suggested by its association with certain HLA haplotypes. Genetic…”
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Extended HLA-DPB1 polymorphism by Reinders, Judith, van Gent, Rogier, Rozemuller, Erik H., Tilanus, Marcel G.J.

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Extended HLA-DPB1 polymorphism: an RNA approach for HLA-DPB1 typing by Reinders, Judith, Rozemuller, Erik H, van Gent, Rogier, Arts-Hilkes, Yvonne H. A, van den Tweel, Jan G, Tilanus, Marcel G. J

“…Most of the 119 human leukocyte antigen (HLA)-DPB1 alleles are defined by polymorphism in six hypervariable regions (HVRs) in exon 2 of the HLA-DPB1 gene. We…”
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Synonymous, but alternatively spliced in HLA-A0111N: HLA-A splicing influences allele expression by Reinders, Judith, Rozemuller, Erik H., Otten, Henny G., Houben, Anna J.S., Dormoy, Anne, Mulder, Arend, van den Tweel, Jan G., Petersen, Eefke J., Tilanus, Marcel G.J.

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HLA-DP4 presents an immunodominant peptide from the RSV G protein to CD4 T cells by de Graaff, Patricia M.A, Heidema, Jojanneke, Poelen, Martien C, van Dijk, Mariska E.A, Lukens, Michael V, van Gestel, Sjef P.J, Reinders, Judith, Rozemuller, Erik, Tilanus, Marcel, Hoogerhout, Peter, van Els, Cecile A.C.M, van der Most, Robbert G, Kimpen, Jan L.L, van Bleek, Grada M

“…CD4 T cells play a crucial role during virus infections by producing antiviral cytokines and by regulating humoral and cellular immune responses. Unfortunately…”
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Microsatellite analysis of the HLA region in head and neck squamous cell carcinoma patients using DNA pools by Reinders, Judith, van der Weide, Petra, Oka, Akira, Sato, Rie, Hayashi, Hideki, Slootweg, Pieter J., Rozemuller, Erik H., Inoko, Hidetoshi, Tilanus, Marcel G.J.

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MICA association with presumed ocular histoplasmosis syndrome (POHS) by Reinders, Judith, Rozemuller, Erik H, Ongkosuwito, Jenny V, Jager, Martine J, Tilanus, Marcel G J, Suttorp-Schulten, Maria S A

“…MHC class I chain related gene A (MICA), a polymorphic and stress-inducible cell surface molecule, is located centromeric to human leukocyte antigen locus B…”
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