Search Results - "Reinbothe, T. M."

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes by Reinbothe, T. M., Alkayyali, S., Ahlqvist, E., Tuomi, T., Isomaa, B., Lyssenko, V., Renström, E.

“…Aims/hypothesis Voltage-gated calcium channels of the L-type have been shown to be essential for rodent pancreatic beta cell function, but data about their…”
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Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes by Axelsson, A. S., Mahdi, T., Nenonen, H. A., Singh, T., Hänzelmann, S., Wendt, A., Bagge, A., Reinbothe, T. M., Millstein, J., Yang, X., Zhang, B., Gusmao, E. G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M., Johnson, J. D., Wollheim, C. B., Derry, J.M.J., Mecham, B., Spégel, P., Mulder, H., Costa, I.G., Zhang, E., Rosengren, A. H.

“…Type 2 diabetes (T2D) is characterized by insulin resistance and impaired insulin secretion, but the mechanisms underlying insulin secretion failure are not…”
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δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin by Briant, L. J. B., Reinbothe, T. M., Spiliotis, I., Miranda, C., Rodriguez, B., Rorsman, P.

“…Key points We used a mouse expressing a light‐sensitive ion channel in β‐cells to understand how α‐cell activity is regulated by β‐cells. Light activation of…”
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[delta]-cells and [beta]-cells are electrically coupled and regulate [alpha]-cell activity via somatostatin by Briant, L J B, Reinbothe, T M, Spiliotis, I, Miranda, C, Rodriguez, B, Rorsman, P

“…Key points We used a mouse expressing a light-sensitive ion channel in [beta]-cells to understand how [alpha]-cell activity is regulated by [beta]-cells. Light…”
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The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes by Reinbothe, Thomas, Alkayyali, Sami, Ahlqvist, Emma, Tuomi, Tiinamaija, Isomaa, Bo, Lyssenko, Valeriya, Renström, Erik

“…AIMS/HYPOTHESIS: Voltage-gated calcium channels of the L-type have been shown to be essential for rodent pancreatic beta cell function, but data about their…”
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Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol by Nagaraj, Vini, Kazim, Abdulla S, Helgeson, Johan, Lewold, Clemens, Barik, Satadal, Buda, Pawel, Reinbothe, Thomas M, Wennmalm, Stefan, Zhang, Enming, Renström, Erik

“…Elevated basal insulin secretion under fasting conditions together with insufficient stimulated insulin release is an important hallmark of type 2 diabetes,…”
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The human L-type calcium channel Ca^sub v^1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes by Reinbothe, T M, Alkayyali, S, Ahlqvist, E, Tuomi, T, Isomaa, B, Lyssenko, V, Renström, E

“…Voltage-gated calcium channels of the L-type have been shown to be essential for rodent pancreatic beta cell function, but data about their presence and…”
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Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes by Rosengren, Anders H, Jokubka, Ramunas, Tojjar, Damon, Granhall, Charlotte, Hansson, Ola, Li, Dai-Qing, Nagaraj, Vini, Reinbothe, Thomas M, Tuncel, Jonatan, Eliasson, Lena, Groop, Leif, Rorsman, Patrik, Salehi, Albert, Lyssenko, Valeriya, Luthman, Holger, Renström, Erik

“…Several common genetic variations have been associated with type 2 diabetes, but the exact disease mechanisms are still poorly elucidated. Using congenic…”
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