Search Results - "Reinartz, Roman"

Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors by Schäfer, Niklas, Gielen, Gerrit H, Rauschenbach, Laurèl, Kebir, Sied, Till, Andreas, Reinartz, Roman, Simon, Matthias, Niehusmann, Pitt, Kleinschnitz, Christoph, Herrlinger, Ulrich, Pietsch, Torsten, Scheffler, Björn, Glas, Martin

“…Molecularly targeted therapies using receptor inhibitors, small molecules or monoclonal antibodies are routinely applied in oncology. Verification of target…”
Get full text

Anticancer Effects of Niclosamide in Human Glioblastoma by WIELAND, Anja, TRAGESER, Daniel, WAHA, Andreas, KOCH, Philipp, FIMMERS, Rolf, PIETSCH, Torsten, YACHNIS, Anthony T, PINCUS, David W, STEINDLER, Dennis A, BRÜSTLE, Oliver, SIMON, Matthias, GLAS, Martin, GOGOLOK, Sabine, SCHEFFLER, Björn, REINARTZ, Roman, HÖFER, Heike, KELLER, Mihaela, LEINHAAS, Anke, SCHELLE, Ramona, NORMANN, Sabine, KLAAS, Lil

“…Glioblastoma is a highly malignant, invariably fatal brain tumor for which effective pharmacotherapy remains an unmet medical need. Screening of a compound…”
Get full text

Residual tumor cells are unique cellular targets in glioblastoma by Glas, Martin, Rath, Barbara H., Simon, Matthias, Reinartz, Roman, Schramme, Anja, Trageser, Daniel, Eisenreich, Ramona, Leinhaas, Anke, Keller, Mihaela, Schildhaus, Hans-Ulrich, Garbe, Stephan, Steinfarz, Barbara, Pietsch, Torsten, Steindler, Dennis A., Schramm, Johannes, Herrlinger, Ulrich, Brüstle, Oliver, Scheffler, Björn

“…Residual tumor cells remain beyond the margins of every glioblastoma (GBM) resection. Their resistance to postsurgical therapy is considered a major driving…”
Get full text

Targeting the Cytosolic Innate Immune Receptors RIG‐I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma by Glas, Martin, Coch, Christoph, Trageser, Daniel, Daßler, Juliane, Simon, Matthias, Koch, Philipp, Mertens, Jerome, Quandel, Tamara, Gorris, Raphaela, Reinartz, Roman, Wieland, Anja, Von Lehe, Marec, Pusch, Annette, Roy, Kristin, Schlee, Martin, Neumann, Harald, Fimmers, Rolf, Herrlinger, Ulrich, Brüstle, Oliver, Hartmann, Gunther, Besch, Robert, Scheffler, Björn

“…Cellular heterogeneity, for example, the intratumoral coexistence of cancer cells with and without stem cell characteristics, represents a potential root of…”
Get full text

Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastoma by Rauschenbach, Laurèl, Wieland, Anja, Reinartz, Roman, Kebir, Sied, Till, Andreas, Darkwah Oppong, Marvin, Dobersalske, Celia, Ullrich, Vivien, Ahmad, Ashar, Jabbarli, Ramazan, Pierscianek, Daniela, Fröhlich, Holger, Simon, Matthias, Brüstle, Oliver, Sure, Ulrich, Glas, Martin, Scheffler, Björn

“…The protease inhibitor ritonavir (RTV) is a clinical-stage inhibitor of the human immunodeficiency virus. In a drug repositioning approach, we here exhibit the…”
Get full text

Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma by Reinartz, Roman, Wang, Shanshan, Kebir, Sied, Silver, Daniel J, Wieland, Anja, Zheng, Tong, Küpper, Marius, Rauschenbach, Laurèl, Fimmers, Rolf, Shepherd, Timothy M, Trageser, Daniel, Till, Andreas, Schäfer, Niklas, Glas, Martin, Hillmer, Axel M, Cichon, Sven, Smith, Amy A, Pietsch, Torsten, Liu, Ying, Reynolds, Brent A, Yachnis, Anthony, Pincus, David W, Simon, Matthias, Brüstle, Oliver, Steindler, Dennis A, Scheffler, Björn

“…Investigation of clonal heterogeneity may be key to understanding mechanisms of therapeutic failure in human cancer. However, little is known on the…”
Get full text

Phase I trial of dovitinib (TKI258) in recurrent glioblastoma by Schäfer, Niklas, Gielen, Gerrit H., Kebir, Sied, Wieland, Anja, Till, Andreas, Mack, Frederic, Schaub, Christina, Tzaridis, Theophilos, Reinartz, Roman, Niessen, Michael, Fimmers, Rolf, Simon, Matthias, Coch, Christoph, Fuhrmann, Christine, Herrlinger, Ulrich, Scheffler, Björn, Glas, Martin

“…Purpose Dovitinib (TKI258) is an oral multi-tyrosine kinase inhibitor of FGFR, VEGFR, PDGFR β, and c-Kit. Since dovitinib is able to cross the blood–brain…”
Get full text

Susceptibility variants for male-pattern baldness on chromosome 20p11 by Hillmer, Axel M, Brockschmidt, Felix F, Hanneken, Sandra, Eigelshoven, Sibylle, Steffens, Michael, Flaquer, Antonia, Herms, Stefan, Becker, Tim, Kortüm, Anne-Katrin, Nyholt, Dale R, Zhao, Zhen Zhen, Montgomery, Grant W, Martin, Nicholas G, Mühleisen, Thomas W, Alblas, Margrieta A, Moebus, Susanne, Jöckel, Karl-Heinz, Bröcker-Preuss, Martina, Erbel, Raimund, Reinartz, Roman, Betz, Regina C, Cichon, Sven, Propping, Peter, Baur, Max P, Wienker, Thomas F, Kruse, Roland, Nöthen, Markus M

“…We carried out a genome-wide association study in 296 individuals with male-pattern baldness (androgenetic alopecia) and 347 controls. We then investigated the…”
Get full text

FUNCTIONAL SUBCLONE PROFILING FOR PREDICTION OF TREATMENT-INDUCED INTRA-TUMOR POPULATION SHIFTS AND DISCOVERY OF RATIONAL DRUG COMBINATIONS IN HUMAN GLIOBLASTOMA by Reinartz, Roman, Wang, Shanshan, Kebir, Sied, Silver, Daniel J., Wieland, Anja, Zheng, Tong, Küpper, Marius, Rauschenbach, Laurèl, Fimmers, Rolf, Shepherd, Timothy M., Trageser, Daniel, Till, Andreas, Schäfer, Niklas, Glas, Martin, Hillmer, Axel M., Cichon, Sven, Smith, Amy A., Pietsch, Torsten, Liu, Ying, Reynolds, Brent A., Yachnis, Anthony, Pincus, David W., Simon, Matthias, Brüstle, Oliver, Steindler, Dennis A., Scheffler, Björn

Get full text

Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 by Hillmer, Axel M., Flaquer, Antonia, Hanneken, Sandra, Eigelshoven, Sibylle, Kortüm, Anne-Katrin, Brockschmidt, Felix F., Golla, Astrid, Metzen, Christine, Thiele, Holger, Kolberg, Susanne, Reinartz, Roman, Betz, Regina C., Ruzicka, Thomas, Hennies, Hans Christian, Kruse, Roland, Nöthen, Markus M.

“…Androgenetic alopecia (AGA, male pattern baldness) is the most common form of hair loss. The origin of AGA is genetic, with the X chromosome located androgen…”
Get full text

Genome-wide Scan and Fine-Mapping Linkage Study of And rogenetic Alopecia Reveals a Locus on Chromosome 3q26 by Hillmer, Axel M, Flaquer, Antonia, Hanneken, Sandra, Eigelshoven, Sibylle, Kortüm, Anne-Katrin, Brockschmidt, Felix F, Golla, Astrid, Metzen, Christine, Thiele, Holger, Kolberg, Susanne, Reinartz, Roman, Betz, Regina C, Ruzicka, Thomas, Hennies, Hans Christian, Kruse, Roland, Nöthen, Markus M

“…Androgenetic alopecia (AGA, male pattern baldness) is the most common form of hair loss. The origin of AGA is genetic, with the X chromosome located androgen…”
Get full text

Susceptibility variants for male-pattern baldness on chromosome 20p11 by HILLMER, Axel M, BROCKSCHMIDT, Felix F, ZHEN ZHEN ZHAO, MONTGOMERY, Grant W, MARTIN, Nicholas G, MÜHLEISEN, Thomas W, ALBLAS, Margrieta A, MOEBUS, Susanne, JÖCKEL, Karl-Heinz, BRÖCKER-PREUSS, Martina, ERBEL, Raimund, REINARTZ, Roman, HANNEKEN, Sandra, BETZ, Regina C, CICHON, Sven, PROPPING, Peter, BAUR, Max P, WIENKER, Thomas F, KRUSE, Roland, NÖTHEN, Markus M, EIGELSHOVEN, Sibylle, STEFFENS, Michael, FLAQUER, Antonia, HERMS, Stefan, BECKER, Tim, KORTÜM, Anne-Katrin, NYHOLT, Dale R

Get full text