Search Results - "Reimer, Jana"

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    CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo by Reimer, Jana, Knöß, Sabine, Labuhn, Maurice, Charpentier, Emmanuelle M, Göhring, Gudrun, Schlegelberger, Brigitte, Klusmann, Jan-Henning, Heckl, Dirk

    Published in Haematologica (Roma) (01-09-2017)
    “…Chromosomal translocations that generate oncogenic fusion proteins are causative for most pediatric leukemias and frequently affect the gene. modeling of…”
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    Journal Article
  2. 2

    Crispr-Cas9 Induced MLL-Rearrangements Cause Clonal Outgrowth in CD34+ Hematopoietic Stem Cells by Reimer, Jana, Knoess, Sabine, Labuhn, Maurice, Charpentier, Emmanuelle Marie, Klusmann, Jan-Henning, Heckl, Dirk

    Published in Blood (03-12-2015)
    “…Reciprocal chromosomal translocations are the causative genetic aberration in almost 60% of the pediatric acute myeloid leukemia cases. Amongst these,…”
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    Journal Article
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