Search Results - "Reimann, A"

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft by Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Thomas III, Marvin L., Clark, Tannia, Lewis, Billeta G., Hoyt, Robert F., Eckhaus, Michael, Pierson III, Richard N., Belli, Aaron J., Wolf, Eckhard, Klymiuk, Nikolai, Phelps, Carol, Reimann, Keith A., Ayares, David, Horvath, Keith A.

“…Preventing xenograft rejection is one of the greatest challenges of transplantation medicine. Here, we describe a reproducible, long-term survival of cardiac…”
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Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak by Bornholdt, Zachary A., Turner, Hannah L., Murin, Charles D., Li, Wen, Sok, Devin, Souders, Colby A., Piper, Ashley E., Goff, Arthur, Shamblin, Joshua D., Wollen, Suzanne E., Sprague, Thomas R., Fusco, Marnie L., Pommert, Kathleen B. J., Cavacini, Lisa A., Smith, Heidi L., Klempner, Mark, Reimann, Keith A., Krauland, Eric, Gerngross, Tillman U., Wittrup, Karl D., Saphire, Erica Ollmann, Burton, Dennis R., Glass, Pamela J., Ward, Andrew B., Walker, Laura M.

“…Antibodies targeting the Ebola virus surface glycoprotein (EBOV GP) are implicated in protection against lethal disease, but the characteristics of the human…”
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Factors associated with ruminal pH at herd level by Geishauser, T, Linhart, N, Neidl, A, Reimann, A

“…The objective of this study was to evaluate factors associated with ruminal pH at herd level. Four hundred and thirty-two cows of a Thuringian dairy herd were…”
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CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection by Thimme, Robert, Wieland, Stefan, Steiger, Carola, Ghrayeb, John, Reimann, Keith A, Purcell, Robert H, Chisari, Francis V

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One‐Year Heterotopic Cardiac Xenograft Survival in a Pig to Baboon Model by Mohiuddin, M. M., Singh, A. K., Corcoran, P. C., Hoyt, R. F., Thomas, M. L., Lewis, B. G. T., Eckhaus, M., Reimann, K. A., Klymiuk, N., Wolf, E., Ayares, D., Horvath, K. A.

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The Intracellular Concentration of Acetyl Phosphate in Escherichia coli Is Sufficient for Direct Phosphorylation of Two-Component Response Regulators by KLEIN, Adam H, SHULLA, Ana, REIMANN, Sylvia A, KEATING, David H, WOLFE, Alan J

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Is mesenteric panniculitis truely a paraneoplastic phenomenon? A matched pair analysis by Gögebakan, Ö, Albrecht, T, Osterhoff, M.A, Reimann, A

“…Abstract Purpose Mesenteric panniculitis (MP) is an underdiagnosed inflammatory condition of mesenteric adipose tissue. Prior studies suggested an association…”
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Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors by Crowley, Andrew R, Osei-Owusu, Nana Yaw, Dekkers, Gillian, Gao, Wenda, Wuhrer, Manfred, Magnani, Diogo M, Reimann, Keith A, Pincus, Seth H, Vidarsson, Gestur, Ackerman, Margaret E

“…Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a…”
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Dual-energy CT for the characterization of urinary calculi: In vitro and in vivo evaluation of a low-dose scanning protocol by Thomas, C., Patschan, O., Ketelsen, D., Tsiflikas, I., Reimann, A., Brodoefel, H., Buchgeister, M., Nagele, U., Stenzl, A., Claussen, C., Kopp, A., Heuschmid, M., Schlemmer, H.-P.

“…The efficiency and radiation dose of a low-dose dual-energy (DE) CT protocol for the evaluation of urinary calculus disease were evaluated. A low-dose…”
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CD40 Blockade Combines with CTLA4Ig and Sirolimus to Produce Mixed Chimerism in an MHC‐Defined Rhesus Macaque Transplant Model by Page, A., Srinivasan, S., Singh, K., Russell, M., Hamby, K., Deane, T., Sen, S., Stempora, L., Leopardi, F., Price, A. A., Strobert, E., Reimann, K. A., Kirk, A. D., Larsen, C. P., Kean, L. S.

“…In murine models, T‐cell costimulation blockade of the CD28:B7 and CD154:CD40 pathways synergistically promotes immune tolerance after transplantation. While…”
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Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model by Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Hoyt, Robert F., Thomas III, Marvin L., Lewis, Billeta G. T., Eckhaus, Michael, Dabkowski, Nicole L., Belli, Aaron J., Reimann, Keith A., Ayares, David, Horvath, Keith A.

“…Background Recently, we have shown that an immunosuppression regimen including costimulation blockade via anti‐CD154 antibody significantly prolongs the…”
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Control of Viremia in Simian Immunodeficiency Virus Infection by CD8$^+$ Lymphocytes by Schmitz, Jörn E., Kuroda, Marcelo J., Santra, Sampa, Sasseville, Vito G., Simon, Meredith A., Lifton, Michelle A., Racz, Paul, Tenner-Racz, Klara, Dalesandro, Margaret, Scallon, Bernhard J., Ghrayeb, John, Forman, Meryl A., Montefiori, David C., Rieber, E. Peter, Letvin, Norman L., Reimann, Keith A.

“…Clinical evidence suggests that cellular immunity is involved in controlling human immunodeficiency virus-1 (HIV-1) replication. An animal model of acquired…”
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Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization by Fouda, G G, Eudailey, J, Kunz, E L, Amos, J D, Liebl, B E, Himes, J, Boakye-Agyeman, F, Beck, K, Michaels, A J, Cohen-Wolkowiez, M, Haynes, B F, Reimann, K A, Permar, S R

“…We investigated the mucosal distribution and neutralization potency of rhesus recombinant versions of the HIV-specific, broadly neutralizing antibody b12…”
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Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses by Boesch, Austin W, Osei-Owusu, Nana Yaw, Crowley, Andrew R, Chu, Thach H, Chan, Ying N, Weiner, Joshua A, Bharadwaj, Pranay, Hards, Rufus, Adamo, Mark E, Gerber, Scott A, Cocklin, Sarah L, Schmitz, Joern E, Miles, Adam R, Eckman, Joshua W, Belli, Aaron J, Reimann, Keith A, Ackerman, Margaret E

“…Antibodies raised in Indian rhesus macaques [ (MM)] in many preclinical vaccine studies are often evaluated for titer, antigen-recognition breadth,…”
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Nondepleting Anti‐CD40‐Based Therapy Prolongs Allograft Survival in Nonhuman Primates by Badell, I. R., Thompson, P. W., Turner, A. P., Russell, M. C., Avila, J. G., Cano, J. A., Robertson, J. M., Leopardi, F. V., Strobert, E. A., Iwakoshi, N. N., Reimann, K. A., Ford, M. L., Kirk, A. D., Larsen, C. P.

“…Costimulation blockade of the CD40/CD154 pathway has been effective at preventing allograft rejection in numerous transplantation models. This strategy has…”
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Suicide Rates Among Active Duty Service Members Compared with Civilian Counterparts, 2005–2014 by Reimann, Carolyn A, Mazuchowski, Edward L

“…Abstract The objective of this study was to compare military suicide rates with civilian suicide rates, adjusting for age and sex differences that exist…”
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Isolation of a monoclonal antibody from a phage display library binding the rhesus macaque MHC class I allomorph Mamu-A1001 by Holman, Nathan, Weinfurter, Jason T, Harsla, Trevor R, Wiseman, Roger W, Belli, Aaron J, Michaels, Anthony J, Reimann, Keith A, DeMars, Robert I, Reynolds, Matthew R

“…Monoclonal antibodies that bind to human leukocyte antigen (HLA) are useful tools for HLA-typing, tracking donor-recipient chimerisms after bone marrow…”
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Antiretroviral Activity of the Anti-CD4 Monoclonal Antibody TNX-355 in Patients Infected with HIV Type 1 by Kuritzkes, Daniel R., Jacobson, Jeffrey, Powderly, William G., Godofsky, Eliot, DeJesus, Edwin, Haas, Frances, Reimann, Keith A., Larson, Jeffrey L., Yarbough, Patrice O., Curt, Valentin, Shanahan, William R.

“…BackgroundWe wished to determine the safety and anti–human immunodeficiency virus (HIV) type 1 activity of single doses of TNX-355, a humanized IgG4 anti-CD4…”
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Role of CD8+ Lymphocytes in Control of Simian Immunodeficiency Virus Infection and Resistance to Rechallenge after Transient Early Antiretroviral Treatment by Lifson, J D, Rossio, J L, Piatak, Jr, M, Parks, T, Li, L, Kiser, R, Coalter, V, Fisher, B, Flynn, B M, Czajak, S, Hirsch, V M, Reimann, K A, Schmitz, J E, Ghrayeb, J, Bischofberger, N, Nowak, M A, Desrosiers, R C, Wodarz, D

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In Vivo Natural Killer Cell Depletion during Primary Simian Immunodeficiency Virus Infection in Rhesus Monkeys by CHOI, Elisa I, REIMANN, Keith A, LETVIN, Norman L

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