Search Results - "Reilly, Nicole Megan"
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Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer
Published in Molecular oncology (01-06-2024)“…Multiple strategies are continuously being explored to expand the drug target repertoire in solid tumors. We devised a novel computational workflow for…”
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Abstract 5900: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Introduction: The bacterial genotoxin colibactin is enriched in colorectal cancer (CRC) and promotes the accumulation of mutations that drive…”
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Abstract A120: Adaptive mutability of colorectal cancers in response to targeted therapies
Published in Molecular cancer therapeutics (01-12-2019)“…Abstract Success in eradicating human cancer with targeted therapies is limited by the emergence of secondary resistance. The prevalent view is that resistance…”
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Abstract B005: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer
Published in Cancer research (Chicago, Ill.) (09-01-2024)“…Abstract Introduction. The bacterial genotoxin colibactin is enriched in colorectal cancer (CRC) and promotes the accumulation of mutations that drive…”
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Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
Published in Cell reports. Medicine (20-02-2024)“…The bacterial genotoxin colibactin promotes colorectal cancer (CRC) tumorigenesis, but systematic assessment of its impact on DNA repair is lacking, and its…”
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