Search Results - "Reilkoff, Ronald A."
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A multi-center phase II randomized clinical trial of losartan on symptomatic outpatients with COVID-19
Published in EClinicalMedicine (01-07-2021)“…The SARS-CoV-2 virus enters cells via Angiotensin-converting enzyme 2 (ACE2), disrupting the renin-angiotensin-aldosterone axis, potentially contributing to…”
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High PEEP extubation as guided by esophageal manometry
Published in Respiratory medicine case reports (01-01-2024)“…The ventilatory management of morbidly obese patients presents an ongoing challenge in the Intensive Care Unit (ICU) as multiple physiologic changes in the…”
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Fibrocytes: emerging effector cells in chronic inflammation
Published in Nature reviews. Immunology (01-06-2011)“…Erica Herzog and colleagues put forward the opinion that fibrocytes, a little-studied population of monocyte-derived cells that have properties of both…”
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Patient Outcomes and Unit Composition With Transition to a High-Intensity ICU Staffing Model: A Before-and-After Study
Published in Critical care explorations (01-02-2023)“…Provider staffing models for ICUs are generally based on pragmatic necessities and historical norms at individual institutions. A better understanding of the…”
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Validation of automated data abstraction for SCCM discovery VIRUS COVID-19 registry: practical EHR export pathways (VIRUS-PEEP)
Published in Frontiers in medicine (04-10-2023)“…Background The gold standard for gathering data from electronic health records (EHR) has been manual data extraction; however, this requires vast resources and…”
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Evaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy
Published in Critical care medicine (01-05-2022)“…To determine whether IV vitamin C therapy reduces 28-day mortality in patients with septic shock. Multicenter, double-blinded, randomized controlled trial. One…”
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Semaphorin 7a+ Regulatory T Cells Are Associated with Progressive Idiopathic Pulmonary Fibrosis and Are Implicated in Transforming Growth Factor-β1―induced Pulmonary Fibrosis
Published in American journal of respiratory and critical care medicine (15-01-2013)“…Lymphocytes are increasingly associated with idiopathic pulmonary fibrosis (IPF). Semaphorin 7a (Sema 7a) participates in lymphocyte activation. To define the…”
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Rapid implementation of a medical student rotation in health systems operations and remote patient care in response to COVID-19
Published in Medical education online (01-12-2022)“…Medical schools initially removed students from clinical rotations at the outset of COVID-19 for safety reasons when students were eager to help and health…”
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Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
Published in Laboratory investigation (01-06-2010)“…Profibrotic cells derived from circulating CD14+ monocytes include fibrocytes and alternatively activated macrophages. These cells are associated with…”
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Senolytics To slOw Progression of Sepsis (STOP-Sepsis) in elderly patients: Study protocol for a multicenter, randomized, adaptive allocation clinical trial
Published in Current controlled trials in cardiovascular medicine (21-10-2024)“…Senescent immune cells exhibit altered gene expression and resistance to apoptosis. The prevalence of these cells increases with age and emerging data…”
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High-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial
Published in International journal of chronic obstructive pulmonary disease (01-01-2016)“…Clinical outcomes are worse in patients with COPD and chronic bronchitis. N-acetylcysteine (NAC) is commonly prescribed for such patients but with uncertain…”
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HIGH POSITIVE END-EXPIRATORY PRESSURE (PEEP) EXTUBATION AS GUIDED BY PESO: A CASE SERIES
Published in Chest (01-10-2022)Get full text
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Evaluating Vitamin C in Septic Shock: A Randomized Controlled Trial of Vitamin C Monotherapy
Published in Critical care medicine (05-01-2022)Get full text
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VALIDATION OF AUTOMATED DATA ABSTRACTION FOR SCCM DISCOVERY VIRUS COVID-19 REGISTRY: PRACTICAL EHR EXPORT PATHWAY
Published in Chest (01-10-2023)Get full text
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Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial
Published in JAMA network open (16-03-2022)“…SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis, contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung…”
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Fibrocytes: emerging effector cells in chronic inflammation
Published in Nature reviews. Immunology (01-06-2011)“…Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in injured organs and have both the inflammatory features of macrophages…”
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