Search Results - "Reiling, Sarah J"

Uptake of a fluorescently tagged chloroquine analogue is reduced in CQ-resistant compared to CQ-sensitive Plasmodium falciparum parasites by Reiling, Sarah J, Rohrbach, Petra

“…Chloroquine (CQ) was the drug of choice for decades in the treatment of falciparum malaria until resistance emerged. CQ is suggested to accumulate in the…”
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Toxoplasma gondii DNA in Tissues of Anadromous Arctic Charr, Salvelinus alpinus, Collected From Nunavik, Québec, Canada by Merks, Harriet, Gomes, Renessa, Zhu, Shawna, Meymandy, Mahdid, Reiling, Sarah J., Bolduc, Sara, Mainguy, Julien, Dixon, Brent R.

“…ABSTRACT Background Toxoplasma gondii is a very common zoonotic parasite in humans and animals worldwide. Human seroprevalence is high in some regions of…”
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White pupae phenotype of tephritids is caused by parallel mutations of a MFS transporter by Ward, Christopher M., Aumann, Roswitha A., Whitehead, Mark A., Nikolouli, Katerina, Leveque, Gary, Gouvi, Georgia, Fung, Elisabeth, Reiling, Sarah J., Djambazian, Haig, Hughes, Margaret A., Whiteford, Sam, Caceres-Barrios, Carlos, Nguyen, Thu N. M., Choo, Amanda, Crisp, Peter, Sim, Sheina B., Geib, Scott M., Marec, František, Häcker, Irina, Ragoussis, Jiannis, Darby, Alistair C., Bourtzis, Kostas, Baxter, Simon W., Schetelig, Marc F.

“…Mass releases of sterilized male insects, in the frame of sterile insect technique programs, have helped suppress insect pest populations since the 1950s. In…”
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A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Québec, Canada by Murall, Carmen Lía, Fournier, Eric, Galvez, Jose Hector, N'Guessan, Arnaud, Reiling, Sarah J, Quirion, Pierre-Olivier, Naderi, Sana, Roy, Anne-Marie, Chen, Shu-Huang, Stretenowich, Paul, Bourgey, Mathieu, Bujold, David, Gregoire, Romain, Lepage, Pierre, St-Cyr, Janick, Willet, Patrick, Dion, Réjean, Charest, Hugues, Lathrop, Mark, Roger, Michel, Bourque, Guillaume, Ragoussis, Jiannis, Shapiro, B. Jesse, Moreira, Sandrine

“…Background Québec was the Canadian province most impacted by COVID-19, with 401,462 cases as of September 24th, 2021, and 11,347 deaths due mostly to a very…”
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Panmixia in the American eel extends to its tropical range of distribution: Biological implications and policymaking challenges by Ulmo‐Diaz, Gabriela, Engman, Augustin, McLarney, William O., Lasso Alcalá, Carlos A., Hendrickson, Dean, Bezault, Etienne, Feunteun, Eric, Prats‐Léon, Fernando L., Wiener, Jean, Maxwell, Robert, Mohammed, Ryan S., Kwak, Thomas J., Benchetrit, José, Bougas, Bérénice, Babin, Charles, Normandeau, Eric, Djambazian, Haig H. V., Chen, Shu‐Huang, Reiling, Sarah J., Ragoussis, Jiannis, Bernatchez, Louis

“…The American eel (Anguilla rostrata) has long been regarded as a panmictic fish and has been confirmed as such in the northern part of its range. In this…”
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Toxoplasma gondii, Sarcocystis sp. and Neospora caninum-like parasites in seals from northern and eastern Canada: potential risk to consumers by Reiling, Sarah J., Measures, Lena, Feng, Sandy, Boone, Ryan, Merks, Harriet, Dixon, Brent R.

“…Zoonotic parasites of seals that are harvested for food may pose a health risk when seal meat or organ tissues of infected animals are eaten raw or…”
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Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation by Pollo, Stephen M J, Reiling, Sarah J, Wit, Janneke, Workentine, Matthew L, Guy, Rebecca A, Batoff, G William, Yee, Janet, Dixon, Brent R, Wasmuth, James D

“…Currently available short read genome assemblies of the tetraploid protozoan parasite Giardia intestinalis are highly fragmented, highlighting the need for…”
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A cloth-based hybridization array system for rapid detection of the food- and waterborne protozoan parasites Giardia duodenalis, Cryptosporidium spp. and Toxoplasma gondii by Reiling, Sarah J., Merks, Harriet, Zhu, Shawna, Boone, Ryan, Corneau, Nathalie, Dixon, Brent R.

“…Protozoan parasites in food or water samples are generally detected using microscopy or PCR followed by Sanger sequencing. However, microscopy is subjective,…”
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Microfluidic biomechanical assay for red blood cells parasitized by Plasmodium falciparum by Guo, Quan, Reiling, Sarah J, Rohrbach, Petra, Ma, Hongshen

“…Red blood cells parasitized by Plasmodium falciparum can be distinguished from uninfected cells and characterized on the basis of reduced deformability. To…”
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Monitoring PfMDR1 transport in Plasmodium falciparum by Reiling, Sarah J, Rohrbach, Petra

“…The Plasmodium falciparum multidrug resistance 1 transporter, PfMDR1, contains five amino acid polymorphisms that are suggested to be involved in altered drug…”
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Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites by Reiling, Sarah J., Krohne, Georg, Friedrich, Oliver, Geary, Timothy G., Rohrbach, Petra

“…Chloroquine (CQ) treatment failure in Plasmodium falciparum parasites has been documented for decades, but the pharmacological explanation of this phenotype is…”
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The NF‐κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance by Ehrhardt, Christina, Rückle, Andrea, Hrincius, Eike R., Haasbach, Emanuel, Anhlan, Darisuren, Ahmann, Katharina, Banning, Carina, Reiling, Sarah J., Kühn, Joachim, Strobl, Stefan, Vitt, Daniel, Leban, Johann, Planz, Oliver, Ludwig, Stephan

“…Summary Ongoing human infections with highly pathogenic avian H5N1 viruses and the emergence of the pandemic swine‐origin influenza viruses (IV) highlight the…”
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The NF-[kappa]B inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance by Ehrhardt, Christina, Rückle, Andrea, Hrincius, Eike R, Haasbach, Emanuel, Anhlan, Darisuren, Ahmann, Katharina, Banning, Carina, Reiling, Sarah J, Kühn, Joachim, Strobl, Stefan, Vitt, Daniel, Leban, Johann, Planz, Oliver, Ludwig, Stephan

“…Summary Ongoing human infections with highly pathogenic avian H5N1 viruses and the emergence of the pandemic swine-origin influenza viruses (IV) highlight the…”
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Highly pathogenic influenza virus infection of the thymus interferes with T lymphocyte development by Vogel, Annette B, Haasbach, Emanuel, Reiling, Sarah J, Droebner, Karoline, Klingel, Karin, Planz, Oliver

“…Highly pathogenic avian influenza viruses (HPAIVs) cause severe disease in humans. Still, the basis for their increased pathogenesis remains unclear…”
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A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum by Edaye, Sonia, Reiling, Sarah J., Leimanis, Mara L., Wunderlich, Juliane, Rohrbach, Petra, Georges, Elias

“…•2-Amino quinoline (ML571) is a substrate for PfMDR1 but not wild-type or mutant PfCRT.•MK571 is specific inhibitor of PfMDR1-mediated drug transport.•MK571…”
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Draft Hybrid Genome Assembly of a Canadian Cyclospora cayetanensis Isolate by Yanta, Christine A, Pollo, Stephen M J, Barta, John R, Reiling, Sarah J, Wasmuth, James D, Dixon, Brent R, Guy, Rebecca A

“…The apicomplexan parasite Cyclospora cayetanensis causes foodborne gastrointestinal disease in humans. Here, we report the first hybrid assembly for C…”
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Large-scale growth of the Plasmodium falciparum malaria parasite in a wave bioreactor by Dalton, John P., Demanga, Corine G., Reiling, Sarah J., Wunderlich, Juliane, Eng, Jenny W.L., Rohrbach, Petra

“…[Display omitted] ► Breakthrough method for the scale-up of synchronous and asynchronous malaria blood stage cultures in wave bioreactor. ► Significant savings…”
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Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia by Pellerin, David, Danzi, Matt C., Wilke, Carlo, Renaud, Mathilde, Fazal, Sarah, Dicaire, Marie-Josée, Scriba, Carolin K., Ashton, Catherine, Yanick, Christopher, Beijer, Danique, Rebelo, Adriana, Rocca, Clarissa, Jaunmuktane, Zane, Sonnen, Joshua A., Larivière, Roxanne, Genís, David, Molina Porcel, Laura, Choquet, Karine, Sakalla, Rawan, Provost, Sylvie, Robertson, Rebecca, Allard-Chamard, Xavier, Tétreault, Martine, Reiling, Sarah J., Nagy, Sara, Nishadham, Vikas, Purushottam, Meera, Vengalil, Seena, Bardhan, Mainak, Nalini, Atchayaram, Chen, Zhongbo, Mathieu, Jean, Massie, Rami, Chalk, Colin H., Lafontaine, Anne-Louise, Evoy, François, Rioux, Marie-France, Ragoussis, Jiannis, Boycott, Kym M., Dubé, Marie-Pierre, Duquette, Antoine, Houlden, Henry, Ravenscroft, Gianina, Laing, Nigel G., Lamont, Phillipa J., Saporta, Mario A., Schüle, Rebecca, Schöls, Ludger, La Piana, Roberta, Synofzik, Matthis, Zuchner, Stephan, Brais, Bernard

“…In this study, a large repeat expansion in a noncoding part of FGF14 was found to cause late-onset cerebellar ataxia, which underscores the importance of…”
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The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance: SC75741, a novel anti-influenza compound by Ehrhardt, Christina, Rückle, Andrea, Hrincius, Eike R., Haasbach, Emanuel, Anhlan, Darisuren, Ahmann, Katharina, Banning, Carina, Reiling, Sarah J., Kühn, Joachim, Strobl, Stefan, Vitt, Daniel, Leban, Johann, Planz, Oliver, Ludwig, Stephan

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