Search Results - "Reiling, Linda"

Targets of complement-fixing antibodies in protective immunity against malaria in children by Reiling, Linda, Boyle, Michelle J., White, Michael T., Wilson, Danny W., Feng, Gaoqian, Weaver, Rupert, Opi, D. Herbert, Persson, Kristina E. M., Richards, Jack S., Siba, Peter M., Fowkes, Freya J. I., Takashima, Eizo, Tsuboi, Takafumi, Mueller, Ivo, Beeson, James G.

“…Antibodies against P . falciparum merozoites fix complement to inhibit blood-stage replication in naturally-acquired and vaccine-induced immunity; however,…”
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Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children by Kurtovic, Liriye, Behet, Marije C, Feng, Gaoqian, Reiling, Linda, Chelimo, Kiprotich, Dent, Arlene E, Mueller, Ivo, Kazura, James W, Sauerwein, Robert W, Fowkes, Freya J I, Beeson, James G

“…Antibodies targeting Plasmodium falciparum sporozoites play a key role in human immunity to malaria. However, antibody mechanisms that neutralize sporozoites…”
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Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development by Richards, Jack S, Arumugam, Thangavelu U, Reiling, Linda, Healer, Julie, Hodder, Anthony N, Fowkes, Freya J I, Cross, Nadia, Langer, Christine, Takeo, Satoru, Uboldi, Alex D, Thompson, Jennifer K, Gilson, Paul R, Coppel, Ross L, Siba, Peter M, King, Christopher L, Torii, Motomi, Chitnis, Chetan E, Narum, David L, Mueller, Ivo, Crabb, Brendan S, Cowman, Alan F, Tsuboi, Takafumi, Beeson, James G

“…The development of effective malaria vaccines and immune biomarkers of malaria is a high priority for malaria control and elimination. Ags expressed by…”
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Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity by Chan, Jo-Anne, Howell, Katherine B, Reiling, Linda, Ataide, Ricardo, Mackintosh, Claire L, Fowkes, Freya J I, Petter, Michaela, Chesson, Joanne M, Langer, Christine, Warimwe, George M, Duffy, Michael F, Rogerson, Stephen J, Bull, Peter C, Cowman, Alan F, Marsh, Kevin, Beeson, James G

“…Plasmodium falciparum is the major cause of malaria globally and is transmitted by mosquitoes. During parasitic development, P. falciparum-infected…”
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Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination by Dobaño, Carlota, Santano, Rebeca, Vidal, Marta, Jiménez, Alfons, Jairoce, Chenjerai, Ubillos, Itziar, Dosoo, David, Aguilar, Ruth, Williams, Nana Aba, Díez-Padrisa, Núria, Ayestaran, Aintzane, Valim, Clarissa, Asante, Kwaku Poku, Owusu-Agyei, Seth, Lanar, David, Chauhan, Virander, Chitnis, Chetan, Dutta, Sheetij, Angov, Evelina, Gamain, Benoit, Coppel, Ross L, Beeson, James G, Reiling, Linda, Gaur, Deepak, Cavanagh, David, Gyan, Ben, Nhabomba, Augusto J, Campo, Joseph J, Moncunill, Gemma

“…Naturally acquired immunity (NAI) to malaria is mainly mediated by IgG antibodies but the subclasses, epitope targets and effector functions have not been…”
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Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity by Chan, Jo-Anne, Wetzel, David, Reiling, Linda, Miura, Kazutoyo, Drew, Damien R, Gilson, Paul R, Anderson, David A, Richards, Jack S, Long, Carole A, Suckow, Manfred, Jenzelewski, Volker, Tsuboi, Takafumi, Boyle, Michelle J, Piontek, Michael, Beeson, James G

“…The development of effective malaria vaccines remains a global health priority. Currently, the most advanced vaccine, known as RTS,S, has only shown modest…”
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Editorial: Advances on the Gametocyte Biology, Host Immunity and Vector Stages to Interrupt the Transmission of Malaria by Chan, Jo-Anne, Ngotho, Priscilla, Amoah, Linda Eva, Sollelis, Lauriane, Reiling, Linda

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Reduced risk of placental parasitemia associated with complement fixation on Plasmodium falciparum by antibodies among pregnant women by Opi, D. Herbert, Boyle, Michelle J, McLean, Alistair R. D, Reiling, Linda, Chan, Jo-Anne, Stanisic, Danielle I, Ura, Alice, Mueller, Ivo, Fowkes, Freya J. I, Rogerson, Stephen J, Beeson, James G

“…Abstract Background The pathogenesis of malaria in pregnancy (MiP) involves accumulation of P. falciparum -infected red blood cells (pRBCs) in the placenta,…”
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The association between naturally acquired IgG subclass specific antibodies to the PfRH5 invasion complex and protection from Plasmodium falciparum malaria by Weaver, Rupert, Reiling, Linda, Feng, Gaoqian, Drew, Damien R., Mueller, Ivo, Siba, Peter M., Tsuboi, Takafumi, Richards, Jack S., Fowkes, Freya J. I., Beeson, James G.

“…Understanding the targets and mechanisms of human immunity to malaria is important for advancing the development of highly efficacious vaccines and serological…”
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Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives by O’Flaherty, Katherine, Ataíde, Ricardo, Zaloumis, Sophie G, Ashley, Elizabeth A, Powell, Rosanna, Feng, Gaoqian, Reiling, Linda, Dondorp, Arjen M, Day, Nicholas P, Dhorda, Mehul, Fairhurst, Rick M, Lim, Pharath, Amaratunga, Chanaki, Pukrittayakamee, Sasithon, Hien, Tran Tinh, Htut, Ye, Mayxay, Mayfong, Faiz, M Abul, Beeson, James G, Nosten, Francois, Simpson, Julie A, White, Nicholas J, Fowkes, Freya J I

“…Abstract Background Antibodies to the blood stages of malaria parasites enhance parasite clearance and antimalarial efficacy. The antibody subclass and…”
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Display of malaria transmission-blocking antigens on chimeric duck hepatitis B virus-derived virus-like particles produced in Hansenula polymorpha by Wetzel, David, Chan, Jo-Anne, Suckow, Manfred, Barbian, Andreas, Weniger, Michael, Jenzelewski, Volker, Reiling, Linda, Richards, Jack S, Anderson, David A, Kouskousis, Betty, Palmer, Catherine, Hanssen, Eric, Schembecker, Gerhard, Merz, Juliane, Beeson, James G, Piontek, Michael

“…Malaria caused by Plasmodium falciparum is one of the major threats to human health globally. Despite huge efforts in malaria control and eradication, highly…”
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Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial by Jagannathan, Prasanna, Kakuru, Abel, Okiring, Jaffer, Muhindo, Mary K, Natureeba, Paul, Nakalembe, Miriam, Opira, Bishop, Olwoch, Peter, Nankya, Felistas, Ssewanyana, Isaac, Tetteh, Kevin, Drakeley, Chris, Beeson, James, Reiling, Linda, Clark, Tamara D, Rodriguez-Barraquer, Isabel, Greenhouse, Bryan, Wallender, Erika, Aweeka, Francesca, Prahl, Mary, Charlebois, Edwin D, Feeney, Margaret E, Havlir, Diane V, Kamya, Moses R, Dorsey, Grant

“…Intermittent preventive treatment of malaria in pregnancy (IPTp) with dihydroartemisinin-piperaquine (IPTp-DP) has been shown to reduce the burden of malaria…”
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Novel Virus-Like Particle Vaccine Encoding the Circumsporozoite Protein of Plasmodium falciparum Is Immunogenic and Induces Functional Antibody Responses in Mice by Kurtovic, Liriye, Wetzel, David, Reiling, Linda, Drew, Damien R, Palmer, Catherine, Kouskousis, Betty, Hanssen, Eric, Wines, Bruce D, Hogarth, P Mark, Suckow, Manfred, Jenzelewski, Volker, Piontek, Michael, Chan, Jo-Anne, Beeson, James G

“…RTS,S is the leading malaria vaccine in development, but has demonstrated only moderate protective efficacy in clinical trials. RTS,S is a virus-like particle…”
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Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies by Persson, Kristina E M, McCallum, Fiona J, Reiling, Linda, Lister, Nicole A, Stubbs, Janine, Cowman, Alan F, Marsh, Kevin, Beeson, James G

“…Antibodies that inhibit Plasmodium falciparum invasion of erythrocytes are believed to be an important component of immunity against malaria. During…”
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Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity by Persson, Kristina E M, Fowkes, Freya J I, McCallum, Fiona J, Gicheru, Nimmo, Reiling, Linda, Richards, Jack S, Wilson, Danny W, Lopaticki, Sash, Cowman, Alan F, Marsh, Kevin, Beeson, James G

“…Abs that inhibit Plasmodium falciparum invasion of erythrocytes form an important component of human immunity against malaria, but key target Ags are largely…”
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Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Plasmodium falciparum Infections by van den Hoogen, Lotus L, Walk, Jona, Oulton, Tate, Reuling, Isaie J, Reiling, Linda, Beeson, James G, Coppel, Ross L, Singh, Susheel K, Draper, Simon J, Bousema, Teun, Drakeley, Chris, Sauerwein, Robert, Tetteh, Kevin K A

“…The majority of malaria infections in low transmission settings remain undetectable by conventional diagnostics. A powerful model to identify antibody…”
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Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria by Chan, Jo-Anne, Drew, Damien R, Reiling, Linda, Lisboa-Pinto, Ashley, Dinko, Bismarck, Sutherland, Colin J, Dent, Arlene E, Chelimo, Kiprotich, Kazura, James W, Boyle, Michelle J, Beeson, James G

“…Vaccines that target gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is…”
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The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria by Reiling, Linda, Richards, Jack S, Fowkes, Freya J I, Wilson, Danny W, Chokejindachai, Watcharee, Barry, Alyssa E, Tham, Wai-Hong, Stubbs, Janine, Langer, Christine, Donelson, John, Michon, Pascal, Tavul, Livingstone, Crabb, Brendan S, Siba, Peter M, Cowman, Alan F, Mueller, Ivo, Beeson, James G

“…Acquired antibodies are important in human immunity to malaria, but key targets remain largely unknown. Plasmodium falciparum reticulocyte-binding-homologue-4…”
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Research priorities for the development and implementation of serological tools for malaria surveillance by Elliott, Salenna R, Fowkes, Freya J I, Richards, Jack S, Reiling, Linda, Drew, Damien R, Beeson, James G

“…Surveillance is a key component of control and elimination programs. Malaria surveillance has been typically reliant on case reporting by health services,…”
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Antigenic Characterization of an Intrinsically Unstructured Protein, Plasmodium falciparum Merozoite Surface Protein 2 by ADDA, Christopher G, MACRAILD, Christopher A, ANDERS, Robin F, REILING, Linda, WYCHERLEY, Kaye, BOYLE, Michelle J, KIENZLE, Vivian, MASENDYCZ, Paul, FOLEY, Michael, BEESON, James G, NORTON, Raymond S

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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