Search Results - "Reijnders, Christianne M.A"

Development of a Full-Thickness Human Gingiva Equivalent Constructed from Immortalized Keratinocytes and Fibroblasts by Buskermolen, Jeroen K, Reijnders, Christianne M A, Spiekstra, Sander W, Steinberg, Thorsten, Kleverlaan, Cornelis J, Feilzer, Albert J, Bakker, Astrid D, Gibbs, Susan

“…Organotypic models make it possible to investigate the unique properties of oral mucosa in vitro. For gingiva, the use of human primary keratinocytes (KC) and…”
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No Haploinsufficiency but Loss of Heterozygosity for EXT in Multiple Osteochondromas by Reijnders, Christianne M.A, Waaijer, Cathelijn J.F, Hamilton, Andrew, Buddingh, Emilie P, Dijkstra, Sander P.D, Ham, John, Bakker, Egbert, Szuhai, Karoly, Karperien, Marcel, Hogendoorn, Pancras C.W, Stringer, Sally E, Bovée, Judith V.M.G

“…Multiple osteochondromas (MO) is an autosomal dominant disorder caused by germline mutations in EXT1 and/or EXT2 . In contrast, solitary osteochondroma (SO) is…”
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Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts by Reijnders, Christianne M A, van Lier, Amanda, Roffel, Sanne, Kramer, Duco, Scheper, Rik J, Gibbs, Susan

“…Currently, human skin equivalents (HSEs) used for in vitro assays (e.g., for wound healing) make use of primary human skin cells. Limitations of primary…”
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Progress and Future Prospectives in Skin-on-Chip Development with Emphasis on the use of Different Cell Types and Technical Challenges by van den Broek, Lenie J., Bergers, Lambert I. J. C., Reijnders, Christianne M. A., Gibbs, Susan

“…Understanding the healthy and diseased state of skin is important in many areas of basic and applied research. Although the field of skin tissue engineering…”
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Mechanical loading modulates phosphate related genes in rat bone by Nepal, Ashwini Kumar, van Essen, Hubertus W, Reijnders, Christianne M A, Lips, Paul, Bravenboer, Nathalie

“…Mechanical loading determines bone mass and bone structure, which involves many biochemical signal molecules. Of these molecules, Mepe and Fgf23 are involved…”
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Immune-competent human skin disease models by Bergers, Lambert I.J.C., Reijnders, Christianne M.A., van den Broek, Lenie J., Spiekstra, Sander W., de Gruijl, Tanja D., Weijers, Ester M., Gibbs, Susan

“…•Skin disease drug development requires immune-competent in vitro human models.•Skin disease examples: fibrosis, autoimmune, psoriasis, cancer and contact…”
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Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia by Reijnders, Christianne M A, Bravenboer, Nathalie, Tromp, Annechien M, Blankenstein, Marinus A, Lips, Paul

“…Mechanical loading plays an essential role in maintaining skeletal integrity. Mechanical stimulation leads to increased bone formation. However, the cellular…”
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Increased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: identification by oligonucleotide microarray by Reijnders, Christianne M A, van Essen, Huib W, van Rens, Birgitte T T M, van Beek, Johannes H G M, Ylstra, Bauke, Blankenstein, Marinus A, Lips, Paul, Bravenboer, Nathalie

“…Skeletal integrity in humans and animals is maintained by daily mechanical loading. It has been widely accepted that osteocytes function as mechanosensors…”
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Intronic deletion and duplication proximal of the EXT1 gene: A novel causative mechanism for multiple osteochondromas by Waaijer, Cathelijn J. F., Winter, Marcel G. T., Reijnders, Christianne M. A., de Jong, Daniëlle, John Ham, S., Bovée, Judith V. M. G., Szuhai, Károly

“…Multiple osteochondromas (MO) is a syndrome in which benign cartilage‐capped neoplasms develop at the surface of the long bones. Most cases are caused by…”
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The molecular and cellular basis of exostosis formation in hereditary multiple exostoses by Reijnders, Christianne M. A., Hogendoorn, Pancras C. W., Bovée, Judith V. M. G.

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