Search Results - "Reijman, M Doortje"

CTCA in children with severe heterozygous familial hypercholesterolaemia: Screening for subclinical atherosclerosis by Reijman, M. Doortje, van den Bosch, Sibbeliene E., Kusters, D. Meeike, Corpeleijn, Willemijn E., Hutten, Barbara A., Kuipers, Irene M., Planken, R. Nils, Wiegman, Albert

“…Familial hypercholesterolemia (FH) is one of the most common genetically inherited disorders in the world. Children with severe heterozygous FH (HeFH), i.e…”
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Current and emerging monoclonal antibodies for treating familial hypercholesterolemia in children by Reijman, M Doortje, Kusters, D Meeike, Wiegman, Albert

“…Heterozygous familial hypercholesterolemia (HeFH) is a common genetic disorder caused by pathogenic variants in the LDL-C metabolism. Lifelong exposure to…”
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Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia by Wiegman, Albert, Greber-Platzer, Susanne, Ali, Shazia, Reijman, M Doortje, Brinton, Eliot A, Charng, Min-Ji, Srinivasan, Shubha, Baker-Smith, Carissa, Baum, Seth, Brothers, Julie A, Hartz, Jacob, Moriarty, Patrick M, Mendell, Jeanne, Bihorel, Sébastien, Banerjee, Poulabi, George, Richard T, Hirshberg, Boaz, Pordy, Robert

“…Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C)…”
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Rationale and design of two trials assessing the efficacy, safety, and tolerability of inclisiran in adolescents with homozygous and heterozygous familial hypercholesterolaemia by Reijman, M Doortje, Schweizer, Anja, Peterson, Amy L H, Bruckert, Eric, Stratz, Christian, Defesche, Joep C, Hegele, Robert A, Wiegman, Albert

“…Inclisiran is a small interfering RNA molecule that reduces low-density lipoprotein cholesterol (LDL-C) by inhibition of proprotein convertase subtilisin/kexin…”
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Lipoprotein(a) levels in children with homozygous familial hypercholesterolaemia: A cross-sectional study by de Boer, Lotte M., Reijman, M. Doortje, Hutten, Barbara A., Wiegman, Albert

“…•29 HoFH children were matched to 101 HeFH and 102 unaffected children.•Children with HoFH had the highest Lp(a) levels.•A gene-dose increase (zero, one, two…”
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Decreased LDL-Cholesterol Exposure Following ANGPTL3 Inhibition Reduces Coronary Plaque Development in Homozygous Familial Hypercholesterolemia by Schonck, Willemijn A.M., Reijman, M. Doortje, Wiegman, Albert, Ibrahim, Shirin, Corpeleijn, Willemijn E., Planken, R. Nils, Hovingh, G. Kees, Stroes, Erik S.G., Nurmohamed, Nick S., Reeskamp, Laurens F.

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Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN by Reijman, M. Doortje, Kusters, D. Meeike, Groothoff, Jaap W., Arbeiter, Klaus, Dann, Eldad J., de Boer, Lotte M., de Ferranti, Sarah D., Gallo, Antonio, Greber-Platzer, Susanne, Hartz, Jacob, Hudgins, Lisa C., Ibarretxe, Daiana, Kayikcioglu, Meral, Klingel, Reinhard, Kolovou, Genovefa D., Oh, Jun, Planken, R. Nils, Stefanutti, Claudia, Taylan, Christina, Wiegman, Albert, Schmitt, Claus Peter

“…Homozygous familial hypercholesterolaemia is a life-threatening genetic condition, which causes extremely elevated LDL-C levels and atherosclerotic…”
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Counseling couples at risk of having a child with homozygous familial hypercholesterolemia – Clinical experience and recommendations by Tromp, Tycho R., Reijman, M. Doortje, Wiegman, Albert, Hovingh, G. Kees, Defesche, Joep C., van Maarle, Merel C., Mathijssen, Inge B.

“…•HoFH requires prompt diagnosis and intensive treatment to prevent CVD in childhood.•Couples both carrying an FH variant run a 25% chance of having a child…”
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Cardiovascular outcomes in patients with homozygous familial hypercholesterolaemia on lipoprotein apheresis initiated during childhood: long-term follow-up of an international cohort from two registries by Reijman, M Doortje, Tromp, Tycho R, Hutten, Barbara A, Hovingh, G Kees, Blom, Dirk J, Catapano, Alberico L, Cuchel, Marina, Dann, Eldad J, Gallo, Antonio, Hudgins, Lisa C, Raal, Frederick J, Ray, Kausik K, Sadiq, Fouzia, Soran, Handrean, Groothoff, Jaap W, Wiegman, Albert, Kusters, D Meeike

“…Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disease characterised by extremely high plasma LDL cholesterol from birth, causing…”
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THE IMPACT OF EVINACUMAB THERAPY ON PEDIATRIC PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS FROM PART B OF A PHASE 3 TRIAL by Wiegman, Albert, Greber-Platzer, Susanne, Ali, Shazia, Singh, Divya, Reijman, M. Doortje, Brinton, Eliot A, Charng, Min-Ji, Srinivasan, Shubha, Baker-Smith, Carissa, Baum, Seth, Brothers, Julie, Hartz, Jacob, Moriarty, Patrick M., Banerjee, Poulabi, George, Richard T, Pordy, Robert

“…ASCVD /CVD Risk Reduction Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein…”
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Efficacy of lipoprotein apheresis initiated in childhood on cardiovascular outcomes in patients with homozygous FH: Data from two international registries by Reijman, M. Doortje, Tromp, Tycho R., Hutten, Barbara, Hovingh, G., Blom, Dirk, Cuchel, Marina, Dann, Eldad J., D'Erasmo, Laura, Gallo, Antonio, Hudgins, Lisa, Raal, Frederick J., Ray, Kausik, Sadiq, Fouzia, Soran, Handrean, Groothoff, Jaap, Wiegman, Albert, Kusters, D. Meeike

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HOFH is a life limiting condition: The life journey of deceased HOFH patients in the HICC registry by Mulder, Janneke W.C.M., Reijman, M. Doortje, Kusters, D. Meeike, Boersma, Eric, Blom, Dirk, Cuchel, Marina, Dann, Eldad J., Freiberger, Tomas, Groselj, Urh, Harada-Shiba, Mariko, Hovingh, G., Ibarretxe, Daiana, Kim, Thanh, Klingel, Reinhard, Raal, Frederick J., Reeskamp, Laurens, Sadiq, Fouzia, Schonck, Willemijn, Truong, Huong, Tromp, Tycho R., Wiegman, Albert, Van Lennep, Jeanine Roeters

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The Long-Term Efficacy and Safety of Evinacumab in Pediatric Patients with Homozygous Familial Hypercholesterolemia by Greber-Platzer, Susanne, Ali, Shazia, Waldron, Alpana, Reijman, M. Doortje, Brinton, Eliot, Charng, Min-Ji, Srinivasan, Shubha, Baker-Smith, Carissa, Baum, Seth, Brothers, Julie, Hartz, Jacob, Moriarty, Patrick, Banerjee, Poulabi, George, Richard, Hirshberg, Boaz, Pordy, Robert, Wiegman, M. Albert

“…Regeneron Pharmaceuticals, Inc. Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder caused primarily by mutations in the low-density…”
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Efficacy and Safety of Evinacumab in Pediatric Patients with Homozygous Familial Hypercholesterolemia by Wiegman, Albert, Greber-Platzer, Susanne, Ali, Shazia, Singh, Divya, Zhang, Yi, Reijman, M Doortje, Brinton, Eliot A, Charng, Min-Ji, Srinivasan, Shubba, Baker-Smith, Carissa, Baum, Seth, Brothers, Julie, Hartz, Jacob, Moriarty, Patrick M, Banerjee, Poulabi, Georga, Richard T, Pordy, Robert

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