Search Results - "Reife, R A"

Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages by Faught, E, Wilder, B J, Ramsay, R E, Reife, R A, Kramer, L D, Pledger, G W, Karim, R M

“…We conducted a randomized double-blind comparison of three doses of the novel antiepileptic drug (AED) topiramate (200, 400, and 600 mg/day) and placebo as…”
Get full text

Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis by DARVEAU, R. P, BELTON, C. M, REIFE, R. A, LAMONT, R. J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Topiramate Monotherapy for Partial Onset Seizures by Sachdeo, Rajesh C., Reife, Ross A., Lim, Pilar, Pledger, Gordon

“…Purpose: Evaluation of topiramate (TPM) as monotherapy in patients with uncontrolled partial onset seizures. Methods: A total of 48 patients were evaluated in…”
Get full text

Topiramate as Adjunctive Therapy in Refractory Partial Epilepsy: Pooled Analysis of Data from Five Double‐Blind, Placebo‐Controlled Trials by Reife, R. A., Pledger, G. W.

“…A pooled analysis of data from five similarly designed double‐blind, placebo‐controlled trials of topiramate (TPM) as add‐on therapy in patients with partial…”
Get full text

Induction of arthritis with monoclonal antibodies to collagen by Terato, K, Hasty, KA, Reife, RA, Cremer, MA, Kang, AH, Stuart, JM

“…mAb were developed from DBA/1 mice immunized with chick type II collagen. A total of 69 IgG antibodies was isolated and characterized. The majority (36%)…”
Get full text

Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation by REIFE, R. A, SHAPIRO, R. A, BAMBER, B. A, BERRY, K. K, MICK, G. E, DARVEAU, R. P

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

A study of topiramate pharmacokinetics and tolerability in children with epilepsy by Rosenfeld, William E, Doose, Dennis R, Walker, Sally A, Baldassarre, James S, Reife, Ross A

“…The pharmacokinetic and safety profile of topiramate as adjunctive therapy was assessed in pediatric patients with epilepsy in an open-label, 4-week,…”
Get full text

Porphyromonas gingivalis Lipopolysaccharide Antagonizes Escherichia coli Lipopolysaccharide at Toll-Like Receptor 4 in Human Endothelial Cells by COATS, Stephen R, REIFE, Robert A, BAINBRIDGE, Brian W, PHAM, Thu-Thao T, DARVEAU, Richard P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Characterization of type V collagenase (gelatinase) in synovial fluid of patients with inflammatory arthritis by Hirose, T, Reife, R A, Smith, Jr, G N, Stevens, R M, Mainardi, C L, Hasty, K A

“…Gelatin degrading matrix metalloproteinases in synovial fluid from 21 patients with inflammatory arthritis were shown to consist of two distinct gene products,…”
Get more information

Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non‐cartilaginous tissues during early mouse development by Sandell, Linda J., Nalin, Andrew M., Reife, Robert A.

“…Type II collagen, generally considered to be characteristic of cartilage, has been localized in specific non‐cartilaginous structures during embryogenesis and…”
Get full text

Gene expression of collagen types IIA and IX correlates with ultrastructural events in early osteoarthrosis: new applications of the rabbit meniscectomy model by Lefkoe, T P, Nalin, A M, Clark, J M, Reife, R A, Sugai, J, Sandell, L J

“…To examine the phenotypic expression and geographic distribution of collagens in early stages of osteoarthrosis and their relationship to ultrastructural…”
Get more information

The role of C5 and T-cell receptor Vb genes in susceptibility to collagen-induced arthritis by SPINELLA, D. G, JEFFERS, J. R, REIFE, R. A, STUART, J. M

“…Collagen-induced arthritis (CIA) is a rodent arthritis model in which immunization with heterologous type II collagen induces an inflammatory polyarthritis…”
Get full text

Assessing pharmacokinetic and pharmacodynamic interactions in clinical trials of antiepileptic drugs by Reife, R A

“…An understanding of the pharmacokinetic and pharmacodynamic properties of a drug is a basic requirement for its clinical use. The investigations of these…”
Get more information

Autoreactivity against matrilin‐1 in a patient with relapsing polychondritis by Buckner, Jane Hoyt, Wu, Jiann‐Jiu, Reife, Robert A., Terato, Kuniaki, Eyre, David R.

“…Relapsing polychondritis (RP) is a rare inflammatory disease of cartilage. Chondritis of the auricular, nasal, and tracheal cartilages predominates in this…”
Get full text

Oncostatin M stimulates excessive extracellular matrix accumulation in a transgenic mouse model of connective tissue disease by BAMBER, B, REIFE, R. A, HAUGEN, H. S, CLEGG, C. H

“…Oncostatin M (OM), a member of the IL-6 gene family, stimulates a variety of functions implicated in wound repair. Transgenic mice that express this cytokine…”
Get full text

The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis by Hasty, K A, Reife, R A, Kang, A H, Stuart, J M

“…Articular cartilage from arthritic joints of rats immunized with type II collagen is severely depleted of proteoglycans. Depletion begins within 48 hours after…”
Get more information

SWR mice are resistant to collagen-induced arthritis but produce potentially arthritogenic antibodies by Reife, R A, Loutis, N, Watson, W C, Hasty, K A, Stuart, J M

“…SWR mice are resistant to collagen-induced arthritis but produce antibodies to type II collagen. To determine if these antibodies have arthritogenic potential,…”
Get more information

Porphyromonas gingivalis Lipopolysaccharide Contains Multiple Lipid A Species That Functionally Interact with Both Toll-Like Receptors 2 and 4 by DARVEAU, Richard P, PHAM, Thu-Thao T, LEMLEY, Kayde, REIFE, Robert A, BAINBRIDGE, Brian W, COATS, Stephen R, HOWALD, William N, SING SING WAY, HAJJAR, Adeline M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

MD-2 Mediates the Ability of Tetra-Acylated and Penta-Acylated Lipopolysaccharides to Antagonize Escherichia coli Lipopolysaccharide at the TLR4 Signaling Complex by Coats, Stephen R, Pham, Thu-Thao T, Bainbridge, Brian W, Reife, Robert A, Darveau, Richard P

“…We have demonstrated previously that tetra-acylated LPS derived from the oral bacterium, Porphyromonas gingivalis, and penta-acylated msbB LPS derived from a…”
Get full text

Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: differential activities of tetra‐ and penta‐acylated lipid A structures on E‐selectin expression and TLR4 recognition by Reife, Robert A., Coats, Stephen R., Al‐Qutub, Montaser, Dixon, Douglas M., Braham, Pamela A., Billharz, Rosalind J., Howald, William N., Darveau, Richard P.

“…Summary Porphyromonas gingivalis is a Gram‐negative bacterium strongly associated with periodontitis, a chronic inflammatory disease of the tissue surrounding…”
Get full text