Search Results - "Reidy, Kimberly"

Molecular mechanisms of diabetic kidney disease by Reidy, Kimberly, Kang, Hyun Mi, Hostetter, Thomas, Susztak, Katalin

“…Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and the single strongest predictor of mortality in patients with diabetes. DKD…”
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Acute Postinfectious Glomerulonephritis by Duong, Minh Dien, Reidy, Kimberly J.

“…Postinfectious glomerulonephritis (PIGN) is a leading cause of acute glomerulonephritis in children. The presentation of PIGN can vary from asymptomatic…”
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Genetic causes of proteinuria and nephrotic syndrome: Impact on podocyte pathobiology by Akchurin, Oleh, Reidy, Kimberly J.

“…In the past 20 years, multiple genetic mutations have been identified in patients with congenital nephrotic syndrome (CNS) and both familial and sporadic focal…”
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Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice by Kang, Hyun Mi, Huang, Shizheng, Reidy, Kimberly, Han, Seung Hyeok, Chinga, Frank, Susztak, Katalin

“…The kidney has a tremendous capacity to regenerate following injury, but factors that govern this response are still largely unknown. We isolated cells from…”
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Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism by Han, Seung Hyeok, Malaga-Dieguez, Laura, Chinga, Frank, Kang, Hyun Mi, Tao, Jianling, Reidy, Kimberly, Susztak, Katalin

“…Renal tubule epithelial cells are high-energy demanding polarized epithelial cells. Liver kinase B1 (LKB1) is a key regulator of polarity, proliferation, and…”
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Association of Preterm Birth with Adverse Glomerular Disease Outcomes in Children and Adults by Isaac, Jaya S, Troost, Jonathan P, Wang, Yujie, Garrity, Kelly, Kaskel, Frederick, Gbadegesin, Rasheed, Reidy, Kimberly J

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Preterm birth and neonatal acute kidney injury: implications on adolescent and adult outcomes by Harer, Matthew W., Charlton, Jennifer R., Tipple, Trent E., Reidy, Kimberly J.

“…As a result of preterm birth, immature kidneys are exposed to interventions in the NICU that promote survival, but are nephrotoxic. Furthermore, the duration…”
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Genetic risk of APOL1 and kidney disease in children and young adults of African ancestry by Reidy, Kimberly J, Hjorten, Rebecca, Parekh, Rulan S

“…Understanding the genetic risk of APOL1 in children and young adults is important given the lifetime risk of hypertension and kidney disease among children of…”
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Semaphorins in kidney development and disease: modulators of ureteric bud branching, vascular morphogenesis, and podocyte-endothelial crosstalk by Reidy, Kimberly, Tufro, Alda

“…Semaphorins are guidance proteins that play important roles in organogenesis and disease. Expression of class 3 semaphorins and their receptors is regulated…”
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Cell and Molecular Biology of Kidney Development by Reidy, Kimberly J., MD, Rosenblum, Norman D., MD

“…Summary Abnormalities of kidney and urinary tract development are the most common cause of end-stage kidney failure in childhood in the United States. Over the…”
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The effect of hemodynamically significant patent ductus arteriosus on acute kidney injury and systemic hypertension in extremely low gestational age newborns by Velazquez, Danitza M., Reidy, Kimberly J., Sharma, Madhu, Kim, Mimi, Vega, Melissa, Havranek, Tomas

“…Background: Acute kidney injury (AKI) in preterm neonates is becoming an increasingly recognized morbidity in the neonatal intensive care unit neonatal…”
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Epithelial-Mesenchymal Transition and Podocyte Loss in Diabetic Kidney Disease by Reidy, Kimberly, MD, Susztak, Katalin, MD, PhD

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Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease by Veron, Delma, Reidy, Kimberly J., Bertuccio, Claudia, Teichman, Jason, Villegas, Guillermo, Jimenez, Juan, Shen, Wa, Kopp, Jeffrey B., Thomas, David B., Tufro, Alda

“…We sought to examine the pathogenic role of excessive VEGF-A expression in podocytes, since it has been reported that diabetic nephropathy and other glomerular…”
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Low Serum Bicarbonate and CKD Progression in Children by Brown, Denver D, Roem, Jennifer, Ng, Derek K, Reidy, Kimberly J, Kumar, Juhi, Abramowitz, Matthew K, Mak, Robert H, Furth, Susan L, Schwartz, George J, Warady, Bradley A, Kaskel, Frederick J, Melamed, Michal L

“…Studies of adults have demonstrated an association between metabolic acidosis, as measured by low serum bicarbonate levels, and CKD progression. We evaluated…”
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Association of GSTM1 Deletion With Progression of CKD in Children: Findings From the Chronic Kidney Disease in Children (CKiD) Study by Levy, Rebecca V., Reidy, Kimberly J., Le, Thu H., David, Victor, Winkler, Cheryl, Xu, Yunwen, Warady, Bradley, Furth, Susan, Kaskel, Frederick, Melamed, Michal L.

“…Loss of function of the product of the GSTM1 gene has been implicated in rapid progression of adult chronic kidney disease (CKD). Its role in pediatric CKD has…”
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Approach to the Child with Hematuria by Brown, Denver D., Reidy, Kimberly J.

“…The causes of macroscopic and microscopic hematuria overlap; both are often caused by urinary tract infections or urethral/bladder irritation. Coexistent…”
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Premature differentiation of nephron progenitor cell and dysregulation of gene pathways critical to kidney development in a model of preterm birth by Cwiek, Aleksandra, Suzuki, Masako, deRonde, Kimberly, Conaway, Mark, Bennett, Kevin M., El Dahr, Samir, Reidy, Kimberly J., Charlton, Jennifer R.

“…Preterm birth is a leading cause of neonatal morbidity. Survivors have a greater risk for kidney dysfunction and hypertension. Little is known about the…”
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Joint Associations of Maternal-Fetal APOL1 Genotypes and Maternal Country of Origin With Preeclampsia Risk by Hong, Xiumei, Rosenberg, Avi Z., Zhang, Boyang, Binns-Roemer, Elizabeth, David, Victor, Lv, Yiming, Hjorten, Rebecca C., Reidy, Kimberly J., Chen, Teresa K., Wang, Guoying, Ji, Yuelong, Simpson, Claire L., Davis, Robert L., Kopp, Jeffrey B., Wang, Xiaobin, Winkler, Cheryl A.

“…Preeclampsia, which disproportionately affects Black women, is a leading cause of preterm delivery and risk for future hypertension and chronic kidney disease…”
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Fetal—Not Maternal—APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry by Reidy, Kimberly J., Hjorten, Rebecca C., Simpson, Claire L., Rosenberg, Avi Z., Rosenblum, Stacy D., Kovesdy, Csaba P., Tylavsky, Frances A., Myrie, Joseph, Ruiz, Bianca L., Haque, Soulin, Mozhui, Khyobeni, Nelson, George W., David, Victor A., Yang, Xiaoping, Suzuki, Masako, Jacob, Jack, Reznik, Sandra E., Kaskel, Frederick J., Kopp, Jeffrey B., Winkler, Cheryl A., Davis, Robert L.

“…Black Americans are at increased risk for preeclampsia. Genetic variants in apolipoprotein L1 (APOL1) account for much of the increased risk for kidney disease…”
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Reduced kidney function and hypertension in adolescents with low birth weight, NHANES 1999–2016 by Brathwaite, Kaye E., Levy, Rebecca V., Sarathy, Harini, Agalliu, Ilir, Johns, Tanya S., Reidy, Kimberly J., Fadrowski, Jeffrey J., Schwartz, George J., Kaskel, Frederick J., Melamed, Michal L.

“…Background Chronic kidney disease (CKD) is a major health problem, and the risk of CKD and hypertension in children born low birth weight (LBW) is…”
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