Search Results - "Reichert, Andreas S"

Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity by Kondadi, Arun Kumar, Anand, Ruchika, Reichert, Andreas S

“…Mitochondria are vital cellular organelles involved in a plethora of cellular processes such as energy conversion, calcium homeostasis, heme biogenesis,…”
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Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent by Wolf, Dane M, Segawa, Mayuko, Kondadi, Arun Kumar, Anand, Ruchika, Bailey, Sean T, Reichert, Andreas S, van der Bliek, Alexander M, Shackelford, David B, Liesa, Marc, Shirihai, Orian S

“…The mitochondrial membrane potential (ΔΨ m ) is the main driver of oxidative phosphorylation (OXPHOS). The inner mitochondrial membrane (IMM), consisting of…”
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Common Principles and Specific Mechanisms of Mitophagy from Yeast to Humans by Kumar, Rajesh, Reichert, Andreas S

“…Mitochondria are double membrane-bound organelles in eukaryotic cells essential to a variety of cellular functions including energy conversion and ATP…”
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Complexome Profiling Identifies TMEM126B as a Component of the Mitochondrial Complex I Assembly Complex by Heide, Heinrich, Bleier, Lea, Steger, Mirco, Ackermann, Jörg, Dröse, Stefan, Schwamb, Bettina, Zörnig, Martin, Reichert, Andreas S., Koch, Ina, Wittig, Ilka, Brandt, Ulrich

“…Macromolecular complexes are essential players in numerous biological processes. They are often large, dynamic, and rather labile; approaches to study them are…”
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Cristae formation—linking ultrastructure and function of mitochondria by Zick, Michael, Rabl, Regina, Reichert, Andreas S.

“…Mitochondria are double-membrane enclosed eukaryotic organelles with a central role in numerous cellular functions. The ultrastructure of mitochondria varies…”
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Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells by Anand, Ruchika, Strecker, Valentina, Urbach, Jennifer, Wittig, Ilka, Reichert, Andreas S

“…Mitochondrial cristae are connected to the inner boundary membrane via crista junctions which are implicated in the regulation of oxidative phosphorylation,…”
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Emerging Roles of the MICOS Complex in Cristae Dynamics and Biogenesis by Anand, Ruchika, Reichert, Andreas S., Kondadi, Arun Kumar

“…Mitochondria are double membrane-enclosed organelles performing important cellular and metabolic functions such as ATP generation, heme biogenesis, apoptosis,…”
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Nix is a selective autophagy receptor for mitochondrial clearance by Novak, Ivana, Kirkin, Vladimir, McEwan, David G, Zhang, Ji, Wild, Philipp, Rozenknop, Alexis, Rogov, Vladimir, Löhr, Frank, Popovic, Doris, Occhipinti, Angelo, Reichert, Andreas S, Terzic, Janos, Dötsch, Volker, Ney, Paul A, Dikic, Ivan

“…Autophagy is the cellular homeostatic pathway that delivers large cytosolic materials for degradation in the lysosome. Recent evidence indicates that autophagy…”
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Nanotherapy and Reactive Oxygen Species (ROS) in Cancer: A Novel Perspective by Brenneisen, Peter, Reichert, Andreas S

“…The incidence of numerous types of cancer has been increasing over recent years, representing the second-most frequent cause of death after cardiovascular…”
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Dynamic subcompartmentalization of the mitochondrial inner membrane by Vogel, Frank, Bornhövd, Carsten, Neupert, Walter, Reichert, Andreas S

“…The inner membrane of mitochondria is organized in two morphologically distinct domains, the inner boundary membrane (IBM) and the cristae membrane (CM), which…”
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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan by Bernhardt, Dominik, Müller, Matthias, Reichert, Andreas S., Osiewacz, Heinz D.

“…Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to…”
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Impact of Amyloid-β on Platelet Mitochondrial Function and Platelet-Mediated Amyloid Aggregation in Alzheimer's Disease by Donner, Lili, Feige, Tobias, Freiburg, Carolin, Toska, Laura Mara, Reichert, Andreas S, Chatterjee, Madhumita, Elvers, Margitta

“…Alzheimer's disease (AD) is characterized by an accumulation of amyloid β (Aβ) peptides in the brain and mitochondrial dysfunction. Platelet activation is…”
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Uniform nomenclature for the mitochondrial contact site and cristae organizing system by Pfanner, Nikolaus, van der Laan, Martin, Amati, Paolo, Capaldi, Roderick A, Caudy, Amy A, Chacinska, Agnieszka, Darshi, Manjula, Deckers, Markus, Hoppins, Suzanne, Icho, Tateo, Jakobs, Stefan, Ji, Jianguo, Kozjak-Pavlovic, Vera, Meisinger, Chris, Odgren, Paul R, Park, Sang Ki, Rehling, Peter, Reichert, Andreas S, Sheikh, M Saeed, Taylor, Susan S, Tsuchida, Nobuo, van der Bliek, Alexander M, van der Klei, Ida J, Weissman, Jonathan S, Westermann, Benedikt, Zha, Jiping, Neupert, Walter, Nunnari, Jodi

“…The mitochondrial inner membrane contains a large protein complex that functions in inner membrane organization and formation of membrane contact sites. The…”
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CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction by Aplak, Elif, von Montfort, Claudia, Haasler, Lisa, Stucki, David, Steckel, Bodo, Reichert, Andreas S, Stahl, Wilhelm, Brenneisen, Peter

“…Cerium (Ce) oxide nanoparticles (CNP; nanoceria) are reported to have cytotoxic effects on certain cancerous cell lines, while at the same concentration they…”
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Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2 by Mendl, Nadine, Occhipinti, Angelo, Müller, Matthias, Wild, Philipp, Dikic, Ivan, Reichert, Andreas S

“…Dysfunctional mitochondria show a reduced capacity for fusion and, as mitochondrial fission is maintained, become spatially separated from the intact network…”
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APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria by Weber, Tobias A, Koob, Sebastian, Heide, Heinrich, Wittig, Ilka, Head, Brian, van der Bliek, Alexander, Brandt, Ulrich, Mittelbronn, Michel, Reichert, Andreas S

“…Mitochondrial cristae morphology is highly variable and altered under numerous pathological conditions. The protein complexes involved are largely unknown or…”
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In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis by Berning, Lena, Scharf, Lisa, Aplak, Elif, Stucki, David, von Montfort, Claudia, Reichert, Andreas S, Stahl, Wilhelm, Brenneisen, Peter

“…Malignant melanoma is an aggressive type of cancer and the deadliest form of skin cancer. Even though enormous efforts have been undertaken, in particular the…”
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Impaired quality control of mitochondria: Aging from a new perspective by Weber, Tobias A., Reichert, Andreas S.

“…Mitochondria fulfill a number of essential cellular functions and play a key role in the aging process. Reactive oxygen species (ROS) are predominantly…”
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Emergence of the mitochondrial reticulum from fission and fusion dynamics by Sukhorukov, Valerii M, Dikov, Daniel, Reichert, Andreas S, Meyer-Hermann, Michael

“…Mitochondria form a dynamic tubular reticulum within eukaryotic cells. Currently, quantitative understanding of its morphological characteristics is largely…”
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Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation by Leuner, Kristina, Schütt, Tanja, Kurz, Christopher, Eckert, Schamim H, Schiller, Carola, Occhipinti, Angelo, Mai, Sören, Jendrach, Marina, Eckert, Gunter P, Kruse, Shane E, Palmiter, Richard D, Brandt, Ulrich, Dröse, Stephan, Wittig, Ilka, Willem, Michael, Haass, Christian, Reichert, Andreas S, Müller, Walter E

“…Intracellular amyloid beta (Aβ) oligomers and extracellular Aβ plaques are key players in the progression of sporadic Alzheimer's disease (AD). Still, the…”
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