Search Results - "Reichardt, Louis"

Neurotrophin-regulated signalling pathways by Reichardt, Louis F

“…Neurotrophins are a family of closely related proteins that were identified initially as survival factors for sensory and sympathetic neurons, and have since…”
Get full text

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity by Arikkath, Jyothi, Reichardt, Louis F

“…Synapse formation involves reciprocal interactions between cells resulting in formation of a structure optimized for efficient information transfer. Recent…”
Get full text

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex by Beaudoin, Gerard M J, Lee, Seung-Hye, Singh, Dipika, Yuan, Yang, Ng, Yu-Gie, Reichardt, Louis F, Arikkath, Jyothi

“…The ability to culture and maintain postnatal mouse hippocampal and cortical neurons is highly advantageous, particularly for studies on genetically engineered…”
Get full text

SPARK: A US Cohort of 50,000 Families to Accelerate Autism Research by Feliciano, Pamela, Daniels, Amy M., Esler, Amy, Gutierrez, Anibal, Nicholson, Amy, Stephens, Alexandra N., Stedman, Amy, Finucane, Brenda, O’Roak, Brian J., Robertson, Beverly E., Rodriguez, Barbara, Van Metre, Bonnie, Bradley, Catherine, Erickson, Craig A., Harkins, Christina, Ochoa-Lubinoff, Cesar, Rosenberg, Cordelia R., Smith, Christopher J., Taylor, Cora M., White, Loran Casey, Walston, Corrie H., Amaral, David G., Coury, Daniel Lee, Sarver, Dustin E., Li, Deana, Berry-Kravis, Elizabeth, Fombonne, Eric J., Hofammann, Eugenia, Wodka, Ericka L., O’Connor, Eirene, Miller, Fiona, Stein, Gail, Hutter, Hanna, Li, Hai, Lechniak, Holly, Schneider, Hoa Lam, Zaydens, Hana, Arriaga, Ivette, Cubells, Joseph F., Cordova, Jeanette M., Gunderson, Jaclyn, McCracken, James T., Michaelson, Jacob J., Neely, Jason, Orobio, Jessica, Piven, Joseph, Tjernagel, Jennifer, Dent, Katherine, Schweers, Kathryn A., Law, J. Kiely, Lowe, Kathryn, O’Brien, Kaela, Smith, Kaitlin, Pawlowski, Katherine G., Pierce, Karen L., Roeder, Katherine, Coppola, Leigh A., Carpenter, Laura, Huang-Storms, Lark Y., Herbert, Lynette M., Simon, Laura, Soorya, Latha V., Wasserburg, Lucy, Lazar, Maya, Currin, Mary Hannah, Heyman, Michelle, Jones, Mark, Jordy, Michelle, Sahin, Mustafa, Siegel, Matthew S., Yinger, Meredith, Hanna, Nathan, Juarez, A. Pablo, Remington, Rick, Schultz, Robert T., Carpenter, Sarah, Eldred, Sara, Francis, Sunday, Horner, Susannah, Lee, Soo J., Mastel, Sarah A., Myers, Vincent J., Amatya, Alpha, Chatha, Ahmad S., Lash, Alex E., Ridenour, Curtis, Stock, Colleen M., Schmidt, Danielle, Butler, Martin E., Carriero, Nicholas, Volfovsky, Natalia, Edgar, Ron, Chin, Wubin, Jensen, William, Krentz, Anthony D., Astrovskaya, Irina, Gibbs, Richard A., Han, Xinwei, Shen, Yufeng, Reichardt, Louis F.

“…The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.org, a dynamic platform that is engaging thousands of individuals with…”
Get full text

Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion by Ishiyama, Noboru, Lee, Seung-Hye, Liu, Shuang, Li, Guang-Yao, Smith, Matthew J., Reichardt, Louis F., Ikura, Mitsuhiko

“…The association of p120 catenin (p120) with the juxtamembrane domain (JMD) of the cadherin cytoplasmic tail is critical for the surface stability of…”
Get full text

The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche by Fujiwara, Hironobu, Ferreira, Manuela, Donati, Giacomo, Marciano, Denise K., Linton, James M., Sato, Yuya, Hartner, Andrea, Sekiguchi, Kiyotoshi, Reichardt, Louis F., Watt, Fiona M.

“…The hair follicle bulge in the epidermis associates with the arrector pili muscle (APM) that is responsible for piloerection (“goosebumps”). We show that stem…”
Get full text

TRK RECEPTORS: ROLES IN NEURONAL SIGNAL TRANSDUCTION by Huang, Eric J, Reichardt, Louis F

“…Trk receptors are a family of three receptor tyrosine kinases, each of which can be activated by one or more of four neurotrophins-nerve growth factor (NGF),…”
Get full text

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling by Pylayeva, Yuliya, Gillen, Kelly M, Gerald, William, Beggs, Hilary E, Reichardt, Louis F, Giancotti, Filippo G

“…Cancer cells require sustained oncogenic signaling in order to maintain their malignant properties. It is, however, unclear whether they possess other…”
Get full text

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking alpha V beta 8-TGF beta signaling in the brain by Arnold, Thomas D, Niaudet, Colin, Pang, Mei-Fong, Siegenthaler, Julie, Gaengel, Konstantin, Jung, Bongnam, Ferrero, Gina M, Mukouyama, Yoh-suke, Fuxe, Jonas, Akhurst, Rosemary, Betsholtz, Christer, Sheppard, Dean, Reichardt, Louis F

“…Vascular development of the central nervous system and blood-brain barrier (BBB) induction are closely linked processes. The role of factors that promote…”
Get full text

p120 Catenin Regulates Dendritic Spine and Synapse Development through Rho-Family GTPases and Cadherins by Elia, Lisa P., Yamamoto, Miya, Zang, Keling, Reichardt, Louis F.

“…Both the cadherin-catenin complex and Rho-family GTPases have been shown to regulate dendrite development. We show here a role for p120 catenin (p120ctn) in…”
Get full text

Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum by Chen, Albert I., Zang, Keling, Masliah, Eliezer, Reichardt, Louis F.

“…To study mechanisms that regulate the construction of inhibitory circuits, we examined the role of brain-derived neurotrophic factor (BDNF) in the assembly of…”
Get full text

BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions by Bamji, Shernaz X, Rico, Beatriz, Kimes, Nikole, Reichardt, Louis F

“…Neurons of the vertebrate central nervous system have the capacity to modify synapse number, morphology, and efficacy in response to activity. Some of these…”
Get full text

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor by Bellmunt, Elena, Zhou, Zheng, Venegas, Victor, Scheib, Jami L, Burkert, Cornelia, Reichardt, Louis F, Fariñas, Isabel, Wu, Hsiao-Huei, Carter, Bruce D

“…During development of the peripheral ganglia, 50% of neurons die by apoptosis. This study finds that satellite glial cell precursors clear these neuronal…”
Get full text

Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction by Arnold, Thomas D, Lizama, Carlos O, Cautivo, Kelly M, Santander, Nicolas, Lin, Lucia, Qiu, Haiyan, Huang, Eric J, Liu, Chang, Mukouyama, Yoh-Suke, Reichardt, Louis F, Zovein, Ann C, Sheppard, Dean

“…Microglia play a pivotal role in the coordination of brain development and have emerged as a critical determinant in the progression of neurodegenerative…”
Get full text

Introduction: The role of extracellular matrix in nervous system development and maintenance by Reichardt, Louis, Prokop, Andreas

Get full text

Loss of integrin αvβ8 on dendritic cells causes autoimmunity and colitis in mice by TRAVIS, Mark A, REIZIS, Boris, BLUESTONE, Jeffrey A, SHEPPARD, Dean, MELTON, Andrew C, MASTELLER, Emma, QIZHI TANG, PROCTOR, John M, YANLI WANG, BERNSTEIN, Xin, XIAOZHU HUANG, REICHARDT, Louis F

“…The cytokine transforming growth factor-β (TGF-β) is an important negative regulator of adaptive immunity 1 – 3 . TGF-β is secreted by cells as an inactive…”
Get full text

TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry by Sanchez-Ortiz, Efrain, Yui, Daishi, Song, Dongli, Li, Yun, Rubenstein, John L, Reichardt, Louis F, Parada, Luis F

“…Dysfunction of basal forebrain cholinergic neurons (BFCNs) is an early pathological hallmark of Alzheimer's disease (AD). Numerous studies have indicated that…”
Get full text

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics by Schober, Markus, Raghavan, Srikala, Nikolova, Maria, Polak, Lisa, Pasolli, H. Amalia, Beggs, Hilary E, Reichardt, Louis F, Fuchs, Elaine

“…In response to αβ1 integrin signaling, transducers such as focal adhesion kinase (FAK) become activated, relaying to specific machineries and triggering…”
Get full text

Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior by Warren, M Sloan, Bradley, William D, Gourley, Shannon L, Lin, Yu-Chih, Simpson, Mark A, Reichardt, Louis F, Greer, Charles A, Taylor, Jane R, Koleske, Anthony J

“…Integrins are heterodimeric extracellular matrix receptors that are essential for the proper development of the vertebrate nervous system. We report here that…”
Get full text

De novo lumen formation and elongation in the developing nephron: a central role for afadin in apical polarity by Yang, Zhufeng, Zimmerman, Susan, Brakeman, Paul R, Beaudoin, 3rd, Gerard M, Reichardt, Louis F, Marciano, Denise K

“…A fundamental process in biology is the de novo formation and morphogenesis of polarized tubules. Although these processes are essential for the formation of…”
Get full text