Search Results - "Reichardt, Juergen K.V."

COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission by Godri Pollitt, Krystal J, Peccia, Jordan, Ko, Albert I, Kaminski, Naftali, Dela Cruz, Charles S, Nebert, Daniel W, Reichardt, Juergen K V, Thompson, David C, Vasiliou, Vasilis

“…The recent coronavirus disease (COVID-19), caused by SARS-CoV-2, is inarguably the most challenging coronavirus outbreak relative to the previous outbreaks…”
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Multiplex automated primer extension analysis: simultaneous genotyping of several polymorphisms by Makridakis, N M, Reichardt, J K

“…Accurate and fast genotyping of single nucleotide polymorphisms (SNPs) is of significant scientific importance for linkage and association studies. We report…”
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Single nucleotide differences (SNDs) in the dbSNP database may lead to errors in genotyping and haplotyping studies by Musumeci, Lucia, Arthur, Jonathan W, Cheung, Florence S.G, Hoque, Ashraful, Lippman, Scott, Reichardt, Juergen K.V

“…The creation of single nucleotide polymorphism (SNP) databases (such as NCBI dbSNP) has facilitated scientific research in many fields. SNP discovery and…”
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Hormones and prostate cancer: Current perspectives and future directions by Hsing, Ann W., Reichardt, Juergen K.V., Stanczyk, Frank Z.

“…Prostate cancer is the most commonly diagnosed non‐skin cancer in men in most western countries. Despite the high morbidity and mortality from prostate cancer,…”
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Effect of Finasteride on Serum Androstenedione and Risk of Prostate Cancer Within the Prostate Cancer Prevention Trial: Differential Effect on High- and Low-grade Disease by Hoque, Ashraful, Yao, Song, Till, Cathee, Kristal, Alan R, Goodman, Phyllis J, Hsing, Ann W, Tangen, Catherine M, Platz, Elizabeth A, Stanczyk, Frank Z, Reichardt, Juergen K.V, vanBokhoven, Adrie, Neuhouser, Marian L, Santella, Regina M, Figg, William D, Price, Douglas K, Parnes, Howard L, Lippman, Scott M, Ambrosone, Christine B, Thompson, Ian M

“…Objective To evaluate the effect of finasteride on serum androst-4-ene-3,17-dione (androstenedione) and its association with prostate cancer risk among…”
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Androgen Receptor CAG Repeat Length and TMPRSS2:ETS Prostate Cancer Risk: Results From the Prostate Cancer Prevention Trial by Figg, William D, Chau, Cindy H, Price, Douglas K, Till, Cathee, Goodman, Phyllis J, Cho, Yonggon, Varella-Garcia, Marileila, Reichardt, Juergen K.V, Tangen, Catherine M, Leach, Robin J, van Bokhoven, Adrie, Thompson, Ian M, Lucia, M. Scott

“…Objective To investigate the association between the length of the polymorphic trinucleotide CAG microsatellite repeats in exon 1 of the AR gene and the risk…”
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Current progress in using vitamin D and its analogs for cancer prevention and treatment by Cheung, Florence SG, Lovicu, Frank J, Reichardt, Juergen KV

“…Vitamin D has long been known for its physiological role in mineral homeostasis through its actions on the intestines, kidneys, parathyroid glands and bone…”
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Androgen receptor CAG repeat length and association with prostate cancer risk: results from the prostate cancer prevention trial by Price, Douglas K, Chau, Cindy H, Till, Cathee, Goodman, Phyllis J, Baum, Caitlin E, Ockers, Sandy B, English, Bevin C, Minasian, Lori, Parnes, Howard L, Hsing, Ann W, Reichardt, Juergen K V, Hoque, Ashraful, Tangen, Catherine M, Kristal, Alan R, Thompson, Ian M, Figg, William D

“…We investigated the association between the length of the polymorphic trinucleotide CAG microsatellite repeats in exon 1 of the AR gene and the risk of…”
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Realizing the full potential of the sequenced human genome by Reichardt, Juergen K.V

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PCR-free method detects high frequency of genomic instability in prostate cancer by Makridakis, Nick M, Phipps, Troy, Srivastav, Sudesh, Reichardt, Juergen K.V

“…Most studies of tumor instability are PCR-based. PCR-based methods may underestimate mutation frequencies of heterogeneous tumor genomes. Using a novel…”
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Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif by Makridakis, Nick M, Caldas Ferraz, Lúcio Fábio, Reichardt, Juergen K.V

“…Somatic mutations are hallmarks of cancer progression. We sequenced 26 matched human prostate tumor and constitutional DNA samples for somatic alterations in…”
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No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned by Pearce, C. Leigh, Van Den Berg, David J., Makridakis, Nick, Reichardt, Juergen K.V., Ross, Ronald K., Pike, Malcolm C., Kolonel, Laurence N., Henderson, Brian E.

“…The steroid 5-alpha reductase type II gene (SRD5A2) encodes the enzyme which converts testosterone (T) to the more active androgen dihydrotestosterone. A…”
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future of the human SNP identification: Which individuals to sequence? by Reichardt, Juergen K.V, Mehrian-Shai, Ruty

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Screening of nine SLC25A13 mutations: their frequency in patients with citrin deficiency and high carrier rates in Asian populations by Kobayashi, Keiko, Bang Lu, Yao, Xian Li, Meng, Nishi, Ikumi, Hsiao, Kwang-Jen, Choeh, Kyuchul, Yang, Yanling, Hwu, Wuh-Liang, Reichardt, Juergen K.V, Palmieri, Ferdinando, Okano, Yoshiyuki, Saheki, Takeyori

“…Deficiency of citrin encoded by SLC25A13 causes adult-onset type II citrullinemia (CTLN2) and idiopathic neonatal hepatitis (NICCD). So far we have diagnosed…”
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The fundamental importance of human galactose metabolism: lessons from genetics and biochemistry by Petry, Klaus G, Reichardt, Juergen K.V

“…Cloning and characterization of all three human galactose-metabolic genes (GALK, GALT and GALE) has led to the identification of a number of mutations which…”
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COVID-19 2022 update: transition of the pandemic to the endemic phase by Biancolella, Michela, Colona, Vito Luigi, Mehrian-Shai, Ruty, Watt, Jessica Lee, Luzzatto, Lucio, Novelli, Giuseppe, Reichardt, Juergen K V

“…COVID-19, which is caused by the SARS-CoV-2, has ravaged the world for the past 2 years. Here, we review the current state of research into the disease with…”
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Pharmacogenetics of human androgens and prostate cancer--an update by Novelli, Giuseppe, Margiotti, Katia, Chiocca, Anna Maria, Spera, Enrico, Micali, Francesco, Reichardt, Juergen K V

“…Prostate cancer is the most common non-skin cancer in the US; it is the second leading cause of death from cancer among US men, and the seventh leading cause…”
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The Gut-Brain Axis, Paving the Way to Brain Cancer by Mehrian-Shai, Ruty, Reichardt, Juergen K V, Harris, Curtis C, Toren, Amos

“…The gut-brain axis formed by blood and lymphatic vessels paves the way for microbiota to impact the brain. Bacterial populations in the gut are a good…”
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Reflections of a Biomedical Scientist on Four Continents in Interdisciplinary Research by Reichardt, Juergen K.V.

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COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy by Novelli, Giuseppe, Biancolella, Michela, Mehrian-Shai, Ruty, Colona, Vito Luigi, Brito, Anderson F, Grubaugh, Nathan D, Vasiliou, Vasilis, Luzzatto, Lucio, Reichardt, Juergen K V

“…COVID-19 has engulfed the world and it will accompany us all for some time to come. Here, we review the current state at the milestone of 1 year into the…”
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