Search Results - "Reich, Jens G"
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ASTD: The Alternative Splicing and Transcript Diversity database
Published in Genomics (San Diego, Calif.) (01-03-2009)“…The Alternative Splicing and Transcript Diversity database (ASTD) gives access to a vast collection of alternative transcripts that integrate transcription…”
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Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression
Published in BMC genomics (13-06-2006)“…Splicing processes might play a major role in carcinogenesis and tumour progression. The Wnt pathway is of crucial relevance for cancer progression. Therefore…”
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Systems analysis of iron metabolism: the network of iron pools and fluxes
Published in BMC systems biology (13-08-2010)“…Every cell of the mammalian organism needs iron as trace element in numerous oxido-reductive processes as well as for transport and storage of oxygen. The very…”
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EASED: Extended Alternatively Spliced EST Database
Published in Nucleic acids research (01-01-2004)“…We established a database of alternative splice forms (ASforms) for nine eukaryotic organisms. ASforms are defined by comparing high‐scoring ESTs with mRNA…”
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Estimating rates of alternative splicing in mammals and invertebrates
Published in Nature genetics (01-09-2004)Get full text
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The Debate in Germany
Published in Science (American Association for the Advancement of Science) (12-04-2002)“…The contentious debate over the use and import of human embryonic stem cells in Germany is examined. Germany has decided that import of human embryonic stem…”
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Embryonic stem cells. The debate in Germany
Published in Science (American Association for the Advancement of Science) (12-04-2002)Get full text
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Concordant association of lipid gene variation with a combined HDL/LDL-cholesterol phenotype in two European populations
Published in Human heredity (01-01-2006)“…SNP/phenotype associations are difficult to validate. This comparative study demonstrates significant contribution of candidate genes to the variation of a…”
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View from the East
Published in Science (American Association for the Advancement of Science) (05-11-1999)“…Reich discusses what the fall of the Berlin Wall has meant for the scientific community of East Germany. It is hoped that the countries of the former socialist…”
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A Database on Alternative Splice Forms on the Integrated Genetic Map Service (IGMS)
Published in In silico biology (2003)“…The IGMS is a comprehensive information system that combines the knowledge from genomic sequence, genetic map and genetic disorders databases. This system is…”
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Single nucleotide polymorphism haplotypes in the cholesteryl-ester transfer protein (CETP) gene and lipid phenotypes
Published in Human heredity (01-01-2002)“…We studied the association between high (HDL) and low-density (LDL) cholesterol concentrations and family-derived haplotypes based on six common SNPs in the…”
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Associative database of protein sequences
Published in Bioinformatics (01-09-1999)“…We present a new concept that combines data storage and data analysis in genome research, based on an associative network memory. As an illustration, 115 000…”
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Estimating rates of alternative splicing in mammals and invertebrates
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Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins
Published in Journal of molecular biology (06-02-1998)“…Using a new method for construction and database searches of sequence consensus strings, we have identified a new superfamily of protein modules comprising…”
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Kohonen map as a visualization tool for the analysis of protein sequences: multiple alignments, domains and segments of secondary structures
Published in Bioinformatics (1996)“…The method of Kohonen maps, a special form of neural networks, was applied as a visualization tool for the analysis of protein sequence similarity. The…”
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Self‐organizing hierarchic networks for pattern recognition in protein sequence
Published in Protein science (01-01-1996)“…We present a method based on hierarchical self‐organizing maps (SOMs) for recognizing patterns in protein sequences. The method is fully automatic, does not…”
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Use of a modified binding model for the investigation of affinity dependence on antibody concentration in immunoassay systems
Published in Journal of immunological methods (25-04-1997)“…Affinity parameters obtained from standard calibration curves of radioimmunoassays (RIA) have been shown to decrease with increasing antibody concentration. A…”
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simple statistical significance test of window scores in large dot matrices obtained from protein or nucleic acid sequences
Published in Bioinformatics (01-03-1987)“…A test of the statistical significance of dot constellations as detected by window search in large dot matrices is described. The procedure takes the…”
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On the statistical assessment of similarities in DNA sequences
Published in Nucleic acids research (11-07-1984)“…The statistical behavior of the similarity score for unrelated DNA sequences calculated as letter-by-letter comparison or from various forms of optimal…”
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