Search Results - "Reiber, Maria"
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Evidence-based comparative severity assessment in young and adult mice
Published in PloS one (20-10-2023)“…In animal-based research, welfare assessments are essential for ethical and legal reasons. However, accurate assessment of suffering in laboratory animals is…”
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2
Development of behavioral patterns in young C57BL/6J mice: a home cage-based study
Published in Scientific reports (15-02-2022)“…Evidence exists that behavioral patterns only stabilize once mice reach adulthood. Detailed information about the course of behavioral patterns is of…”
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Phenotyping Young GluA1 Deficient Mice – A Behavioral Characterization in a Genetic Loss-of-Function Model
Published in Frontiers in behavioral neuroscience (02-06-2022)“…Alterations of glutamatergic neurotransmission have been implicated in neurodevelopmental and neuropsychiatric disorders. Mice lacking the GluA1 AMPA receptor…”
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4
An exploratory approach to identify microRNAs as circulatory biomarker candidates for epilepsy-associated psychiatric comorbidities in an electrical post-status epilepticus model
Published in Scientific reports (20-03-2023)“…Patients with epilepsy have a high risk of developing psychiatric comorbidities, and there is a particular need for early detection of these comorbidities…”
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Anesthesia and analgesia for experimental craniotomy in mice and rats: a systematic scoping review comparing the years 2009 and 2019
Published in Frontiers in neuroscience (03-05-2023)“…Experimental craniotomies are a common surgical procedure in neuroscience. Because inadequate analgesia appears to be a problem in animal-based research, we…”
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Molecular alterations of the TLR4-signaling cascade in canine epilepsy
Published in BMC veterinary research (20-01-2020)“…Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling…”
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Behavioral phenotyping of young Scn1a haploinsufficient mice
Published in Epilepsy & behavior (01-11-2022)“…•Scn1a-A1783V haploinsufficient mice display age-dependent phenotypic alterations.•The course of behavioral patterns confirmed the overall face validity of the…”
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A systematic assessment of robustness in CNS safety pharmacology
Published in British journal of pharmacology (10-10-2024)“…Irwin tests are key preclinical study elements for characterising drug-induced neurological side effects. This multicentre study aimed to assess the robustness…”
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