Search Results - "Rehnitz, Julia"
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Regulation of Bone Morphogenetic Protein Receptor Type II Expression by FMR1 /Fragile X Mental Retardation Protein in Human Granulosa Cells in the Context of Poor Ovarian Response
Published in International journal of molecular sciences (01-10-2024)“…Fragile X mental retardation protein (FMRP) is a translational repressor encoded by . It targets bone morphogenetic protein receptor type II (BMPR2), which…”
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Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression
Published in Reproductive biology and endocrinology (05-03-2022)“…The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in…”
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Genetische Grundlagen bei Varianten der Geschlechtsentwicklung
Published in Gynäkologische Endokrinologie (01-02-2021)“…Zusammenfassung Ursachen für das Auftreten von Varianten der Geschlechtsentwicklung („differences of sex development“ [DSD]) sind mannigfaltig und können sich…”
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FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve
Published in Reproductive biology and endocrinology (07-07-2018)“…Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5'-UTR a…”
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Genomic instability in individuals with sex determination defects and germ cell cancer
Published in Cell death discovery (23-05-2023)“…The ability to transmit genetic information through generations depends on the preservation of genome integrity. Genetic abnormalities affect cell…”
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Prämature Ovarialinsuffizienz – von der Diagnostik bis zur Therapie
Published in Gynäkologische Endokrinologie (01-05-2023)“…Zusammenfassung Etwa 2–3,6 % aller Frauen sind von einer prämaturen Ovarialinsuffizienz (POI) mit Sistieren der ovariellen Funktion vor dem 40. Lebensjahr…”
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Molekularngenetik bei „premature ovarian insufficiency“: von der Störung der Follikulogenese bis zur POI
Published in Journal für Gynäkologische Endokrinologie (Ausg. Schweiz) (23-05-2024)“…Die Eizelle und die sie umgebenden somatischen Zellen unterliegen einer komplexen genetischen Regulation während der Follikulogenese. Hierbei ist eine Vielzahl…”
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Molekulargenetik bei „premature ovarian insufficiency“: von der Störung der Follikulogenese bis zur POI
Published in Journal für Gynäkologische Endokrinologie (Ausg. Schweiz) (2024)“…Zusammenfassung Die Eizelle und die sie umgebenden somatischen Zellen unterliegen einer komplexen genetischen Regulation während der Follikulogenese. Hierbei…”
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Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-07-2021)“…In order to improve ART outcome, non-invasive embryo assessment is gaining more and more attention. Therefore, the aim of this study is to determine the…”
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Prämature Ovarialinsuffizienz (POI)
Published in Gynäkologe (Berlin) (01-07-2021)“…Zusammenfassung Für die weibliche Fertilität sind Eizellreifung und Eizellreserve von entscheidender Bedeutung. Bei den meisten Frauen tritt im Alter von…”
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FMR1 expression in human granulosa cells and variable ovarian response: control by epigenetic mechanisms
Published in Molecular human reproduction (05-02-2021)“…Abstract In humans, FMR1 (fragile X mental retardation 1) is strongly expressed in granulosa cells (GCs) of the female germline and apparently controls…”
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FMR1 and AKT/mTOR signalling pathways: potential functional interactions controlling folliculogenesis in human granulosa cells
Published in Reproductive biomedicine online (01-11-2017)“…Granulosa cells (GCs) play a major role in folliculogenesis and are crucial for oocyte maturation and growth. In these cells, the mTOR/AKT signalling pathway…”
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Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway
Published in Reproduction (Cambridge, England) (01-12-2017)“…Main goal of this study is to detect the possible alterations in microRNA (miRNA) expression and the pathway targeted in plasma at the time of embryo transfer…”
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Labordiagnostik bei prämaturer Ovarialinsuffizienz (POI)
Published in Gynäkologe (Berlin) (01-11-2019)“…Zusammenfassung Hintergrund Die prämature Ovarialinsuffizienz (POI) betrifft 1 % der Frauen unter 40 Jahren mit meist bleibender Sterilität und…”
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Expression of FMRpolyG in Peripheral Blood Mononuclear Cells of Women with Fragile X Mental Retardation 1 Gene Premutation
Published in Genes (01-03-2022)“…Fragile X-associated primary ovarian insufficiency (FXPOI) is characterized by oligo/amenorrhea and hypergonadotropic hypogonadism and is caused by the…”
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Factors Influencing Success Rate of Intracytoplasmic Sperm Injection with Azoospermic Male Patients
Published in Geburtshilfe und Frauenheilkunde (01-07-2020)“…Abstract Introduction Azoospermia affects about 1% of men, of whom up to 15% inquire about infertility treatment. Information about predictive factors for…”
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FMR1 and AKT/mTOR Signaling in Human Granulosa Cells: Functional Interaction and Impact on Ovarian Response
Published in Journal of clinical medicine (30-08-2021)“…We aimed to determine whether a functional link with impact on female ovarian reserve exists between FMR1 expression and expression ratios of AKT/mTOR…”
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