Search Results - "Rehman, MD Tabish"

Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy by Shamsi, Anas, Mohammad, Taj, Anwar, Saleha, AlAjmi, Mohamed F, Hussain, Afzal, Rehman, Md Tabish, Islam, Asimul, Hassan, Md Imtaiyaz

“…Due to the lack of efficient therapeutic options and clinical trial limitations, the FDA-approved drugs can be a good choice to handle Coronavirus disease…”
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Copper(II) complexes as potential anticancer and Nonsteroidal anti-inflammatory agents: In vitro and in vivo studies by Hussain, Afzal, AlAjmi, Mohamed Fahad, Rehman, Md. Tabish, Amir, Samira, Husain, Fohad Mabood, Alsalme, Ali, Siddiqui, Maqsood Ahmad, AlKhedhairy, Abdulaziz A., Khan, Rais Ahmad

“…Copper-based compounds are promising entities for target-specific next-generation anticancer and NSAIDS therapeutics. In lieu of this, benzimidazole scaffold…”
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Heavy metal pollution and risk assessment by the battery of toxicity tests by Khan, Mohd. Shahnawaz, Javed, Mehjbeen, Rehman, Md. Tabish, Urooj, Maryam, Ahmad, Md. Irshad

“…The current study was carried out on dominant fish Oreochromis niloticus and water collected from the polluted Yamuna River, Agra, India. The heavy metals in…”
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Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy by Gupta, Preeti, Mohammad, Taj, Khan, Parvez, Alajmi, Mohamed F., Hussain, Afzal, Rehman, Md. Tabish, Hassan, Md. Imtaiyaz

“…[Display omitted] •Inhibitory potential of ellagic acid to SphK1 was evaluated using molecular docking, binding and kinase inhibition studies.•Ellagic acid…”
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Concatenation of molecular docking and molecular simulation of BACE-1, γ-secretase targeted ligands: in pursuit of Alzheimer's treatment by Jabir, Nasimudeen R., Rehman, Md. Tabish, Alsolami, Khadeejah, Shakil, Shazi, Zughaibi, Torki A., Alserihi, Raed F., Khan, Mohd. Shahnawaz, AlAjmi, Mohamed F., Tabrez, Shams

“…Alzheimer's disease (AD), the most predominant cause of dementia, has evolved tremendously with an escalating frequency, mainly affecting the elderly…”
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Ethylene reduces glucose sensitivity and reverses photosynthetic repression through optimization of glutathione production in salt-stressed wheat (Triticum aestivum L.) by Sehar, Zebus, Iqbal, Noushina, Khan, M. Iqbal R., Masood, Asim, Rehman, Md. Tabish, Hussain, Afzal, AlAjmi, Mohamed F., Ahmad, Altaf, Khan, Nafees A.

“…Ethylene plays a crucial role throughout the life cycle of plants under optimal and stressful environments. The present study reports the involvement of…”
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Evaluation of Transition Metal Complexes of Benzimidazole-Derived Scaffold as Promising Anticancer Chemotherapeutics by Hussain, Afzal, AlAjmi, Mohamed F, Rehman, Md Tabish, Khan, Azmat Ali, Shaikh, Perwez Alam, Khan, Rais Ahmad

“…Three new transition metal complexes, Cu(II) , Co(II) , and Zn(II) with ligand “bimnap” derived from 1-methyl-2-aminobenzimidazole and 2-hydroxynapthaldehyde…”
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Molecular interaction of tea catechin with bovine β-lactoglobulin: A spectroscopic and in silico studies by Al-Shabib, Nasser Abdulatif, Khan, Javed Masood, Malik, Ajamaluddin, Tabish Rehman, Md, AlAjmi, Mohamed F., Husain, Fohad Mabood, Hisamuddin, Malik, Altwaijry, Nojood

“…Polyphenols has attained pronounced attention due to their beneficial values of health and found to prevent several chronic diseases. Here, we elucidated…”
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MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy by Shamsi, Anas, Anwar, Saleha, Mohammad, Taj, Alajmi, Mohamed F, Hussain, Afzal, Rehman, Md Tabish, Hasan, Gulam Mustafa, Islam, Asimul, Hassan, Md Imtaiyaz

“…Microtubule affinity-regulating kinase (MARK4) plays a key role in Alzheimer's disease (AD) development as its overexpression is directly linked to increased…”
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Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study by Parvez, Mohammad K., Tabish Rehman, Md, Alam, Perwez, Al-Dosari, Mohammed S., Alqasoumi, Saleh I., Alajmi, Mohammed F.

“…Despite high anti-HBV efficacies, while the nucleoside analogs (e.g., lamivudine) lead to the emergence of drug-resistance, interferons (e.g., IFN-α causes…”
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Biosynthesized Silver Nanoparticle (AgNP) From Pandanus odorifer Leaf Extract Exhibits Anti-metastasis and Anti-biofilm Potentials by Hussain, Afzal, Alajmi, Mohamed F, Khan, Meraj A, Pervez, Syed A, Ahmed, Faheem, Amir, Samira, Husain, Fohad M, Khan, Mohd S, Shaik, Gouse M, Hassan, Iftekhar, Khan, Rais A, Rehman, Md Tabish

“…Cancer and the associated secondary bacterial infections are leading cause of mortality, due to the paucity of effective drugs. Here, we have synthesized…”
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Box-Behnken Design (BBD)-Based Optimization of Microwave-Assisted Extraction of Parthenolide from the Stems of Tarconanthus camphoratus and Cytotoxic Analysis by Alam, Perwez, Siddiqui, Nasir Ali, Rehman, Md Tabish, Hussain, Afzal, Akhtar, Ali, Mir, Showkat R, Alajmi, Mohamed Fahad

“…Parthenolide, a strong cytotoxic compound found in different parts of which motivated the authors to develop an optimized microwave-assisted extraction (MEA)…”
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Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1 by Choudhury, Arunabh, Mohammad, Taj, Samarth, Nikhil, Hussain, Afzal, Rehman, Md. Tabish, Islam, Asimul, Alajmi, Mohamed F., Singh, Shailza, Hassan, Md. Imtaiyaz

“…Conserved telomere maintenance component 1 (CTC1) is an important component of the CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of…”
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Comprehensive in silico discovery of c-Src tyrosine kinase inhibitors in cancer treatment: A unified approach combining pharmacophore modeling, 3D QSAR, DFT, and molecular dynamics simulation by Khamouli, Saida, Tabish Rehman, Md, Zegheb, Nadjiba, Hussain, Afzal, Khan, Meraj A.

“…To investigate c-Src, a non-receptor tyrosine kinase dysregulated in various cancer types including colon, breast, and pancreatic cancers, as a potential drug…”
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Design, Synthesis, and Biological Evaluation of Benzimidazole-Derived Biocompatible Copper(II) and Zinc(II) Complexes as Anticancer Chemotherapeutics by AlAjmi, Mohamed F, Hussain, Afzal, Rehman, Md Tabish, Khan, Azmat Ali, Shaikh, Perwez Alam, Khan, Rais Ahmad

“…Herein, we have synthesized and characterized a new benzimidazole-derived "BnI" ligand and its copper(II) complex, [Cu(BnI)₂], , and zinc(II) complex,…”
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Unraveling Binding Mechanism of Alzheimer's Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases by Shamsi, Anas, Mohammad, Taj, Khan, Mohd Shahnawaz, Shahwan, Moyad, Husain, Fohad Mabood, Rehman, Md Tabish, Hassan, Md Imtaiyaz, Ahmad, Faizan, Islam, Asimul

“…Studying drug-protein interactions has gained significant attention lately, and this is because the majority of drugs interact with proteins, thereby altering…”
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Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight by Shamsi, Anas, Shahwan, Moyad, Khan, Mohd Shahnawaz, Husain, Fohad Mabood, Alhumaydhi, Fahad A, Aljohani, Abdullah S. M, Rehman, Md. Tabish, Hassan, Md. Imtaiyaz, Islam, Asimul

“…Recent research has advocated the significant contribution of metal dyshomeostasis in developing and progressing Alzheimer’s disease (AD). Disruption of…”
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Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome by Amir, Mohd, Mohammad, Taj, Kumar, Vijay, Alajmi, Mohammed F, Rehman, Md Tabish, Hussain, Afzal, Alam, Perwez, Dohare, Ravins, Islam, Asimul, Ahmad, Faizan, Hassan, Md Imtaiyaz

“…The human CST complex (CTC1-STN1-TEN1) is associated with telomere functions including genome stability. We have systemically analyzed the sequence of STN and…”
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Identification of Sphingosine Kinase‑1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy by Jairajpuri, Deeba Shamim, Mohammad, Taj, Adhikari, Kirtika, Gupta, Preeti, Hasan, Gulam Mustafa, Alajmi, Mohamed F, Rehman, Md. Tabish, Hussain, Afzal, Hassan, Md. Imtaiyaz

“…Sphingosine kinase 1 (SphK1) is an oncogenic lipid kinase that catalyzes the formation of sphingosine-1-phosphate via phosphorylation of sphingosine and known…”
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Cytotoxicity and molecular docking analysis of racemolactone I, a new sesquiterpene lactone isolated from Inula racemosa by Alam, Perwez, Tyagi, Rama, Farah, Mohammad Abul, Rehman, Md. Tabish, Hussain, Afzal, AlAjmi, Mohamed Fahad, Siddiqui, Nasir Ali, Al-Anazi, Khalid Mashay, Amin, Saima, Mujeeb, Mohd, Mir, Showkat R.

“…Traditionally, Inula racemosa Hook. f. (Asteraceae) has been reported to be effective in cancer treatment which motivated the authors to explore the plant for…”
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