Search Results - "Rehman, Asim"
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Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures
Published in Journal of advanced research (01-02-2022)“…[Display omitted] •Skin cancer is a fatal public health concern rising continuously all over the world.•Several environmental and genetic risk factors are…”
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Major Depressive Disorder: Existing Hypotheses about Pathophysiological Mechanisms and New Genetic Findings
Published in Genes (06-04-2022)“…Major depressive disorder (MDD) is a common mental disorder generally characterized by symptoms associated with mood, pleasure and effectiveness in daily life…”
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Folate decorated chitosan-chondroitin sulfate nanoparticles loaded hydrogel for targeting macrophages against rheumatoid arthritis
Published in Carbohydrate polymers (01-03-2024)“…Inflammatory cell infiltration, particularly macrophages, plays a major contribution to the pathogenesis of Rheumatoid Arthritis (RA). Exploiting the…”
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Recent applications of PLGA based nanostructures in drug delivery
Published in Colloids and surfaces, B, Biointerfaces (01-11-2017)“…PLGA (Illustrated with purple colour) based nanostructures for drug delivery. Figure illustrates the salient features of PLGA (i.e., biocompatibility,…”
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Microneedle liquid injection system assisted delivery of infection responsive nanoparticles: A promising approach for enhanced site-specific delivery of carvacrol against polymicrobial biofilms-infected wounds
Published in International journal of pharmaceutics (25-09-2020)“…[Display omitted] •AdminPen® 1500/1200 can deliver higher doses of liquid formulation in contrast to AdminPen® 777.•CAR-PCL NPs can kill the biofilm grown…”
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6
Nanotechnology: from In Vivo Imaging System to Controlled Drug Delivery
Published in Nanoscale research letters (17-08-2017)“…Science and technology have always been the vitals of human’s struggle, utilized exclusively for the development of novel tools and products, ranging from…”
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Exploiting proteases for cancer theranostic through molecular imaging and drug delivery
Published in International journal of pharmaceutics (25-09-2020)“…[Display omitted] The measurement of biological processes at a molecular and cellular level serves as a basis for molecular imaging. As compared with…”
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Surfactant-Free, Self-Assembled Nanomicelles-Based Transdermal Hydrogel for Safe and Targeted Delivery of Methotrexate against Rheumatoid Arthritis
Published in ACS nano (28-04-2020)“…Methotrexate (MTX) is the first line agent for therapy against rheumatoid arthritis (RA); however, orally its efficacy is hampered by poor solubility, less…”
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Development and validation of HPLC method for simultaneous determination of Leflunomide and folic acid in the nanoparticulate system by reversed-phase HPLC
Published in Drug development and industrial pharmacy (03-08-2023)“…The main objective of this study was to develop a highly sensitive, accurate, and reproducible analytical method for the simultaneous detection of LEF and FA…”
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Development of novel biopolymer-based nanoparticles loaded cream for potential treatment of topical fungal infections
Published in Drug development and industrial pharmacy (03-07-2021)“…Biodegradable polymers are extensively used due to their efficient safety profiles. The aim of the current study was to fabricate, evaluate, and characterize…”
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Biodegradable Ingredient-Based Emulgel Loaded with Ketoprofen Nanoparticles
Published in AAPS PharmSciTech (01-05-2018)“…Biodegradable materials are extensively employed to design nanocarriers that mimic extracellular environment in arthritis. The aim of this study was to…”
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Ligand decorated chitosan as an advanced nanocarrier for targeted delivery: a critical review
Published in Nanomedicine (London, England) (01-06-2019)“…Nontargeted delivery systems present nonspecific delivery, low transfection efficiency and high toxicity. Ligand-conjugated chitosan (CS) nanocarriers have…”
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Exploiting Recent Trends in the Treatment of Androgenic Alopecia through Topical Nanocarriers of Minoxidil
Published in AAPS PharmSciTech (01-11-2022)“…Androgenic alopecia, a polygenetic disorder, is characterized by well-defined hair loss that progresses gradually. The disease affects both males and females…”
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14
In Silico identification of novel phytochemicals that target SFRP4: An early biomarker of diabesity
Published in PloS one (09-11-2023)“…The simultaneous coexistence of complicated metabolic conditions like obesity and diabetes within an individual is known as diabesity. Obesity is the key…”
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Diagnostic Value of Dynamic Ultrasonography in Detection of Meniscal Injury in Correlation with MRI Knee findings keeping it as Reference Standard
Published in Pakistan journal of medical research (30-06-2023)“…Abstract Background: MRI knee is an expensive modality for diagnosis of meniscal injury. Ultrasound can be confidently used as a diagnostic tool. Objective: To…”
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16
Polysaccharide Chemistry in Drug Delivery, Endocrinology, and Vaccines
Published in Chemistry : a European journal (10-06-2021)“…Polysaccharides, due to their outstanding properties, have attracted the attention of researchers, working in the biomedical field and especially of those…”
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New, Environment Friendly Approach for Synthesis of Amphiphilic PCL–PEG–PCL Triblock Copolymer: An Efficient Carrier for Fabrication of Nanomicelles
Published in Journal of polymers and the environment (01-04-2020)“…Ring opening copolymerization is the most frequently applied reaction for the synthesis of polycaprolactone–polyethylene glycol–polycaprolactone (PCL–PEG–PCL)…”
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Development and Evaluation of Optimized Thiolated Chitosan Proniosomal Gel Containing Duloxetine for Intranasal Delivery
Published in AAPS PharmSciTech (01-10-2019)“…Proniosomes offer excellent potential for improved drug delivery, through versatile routes, by overcoming the permeation barriers faced by several drugs. The…”
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Proniosomes as a carrier system for transdermal delivery of clozapine
Published in Drug development and industrial pharmacy (02-06-2020)“…The current study aimed to formulate the clozapine (CLZ) loaded proniosomal (PN) gel and evaluate its in vitro release, ex vivo permeation and gel properties…”
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Development of an intelligent, stimuli-responsive transdermal system for efficient delivery of Ibuprofen against rheumatoid arthritis
Published in International journal of pharmaceutics (15-12-2021)“…[Display omitted] The present study aimed to fabricate and evaluate the therapeutic efficacy of pH-responsive Ibuprofen (IB) nanoparticles (NPs) loaded…”
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