Search Results - "Reh, Shelley"

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    Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses by Lange, Sabine S, Bedford, Ella, Reh, Shelley, Wittschieben, John P, Carbajal, Steve, Kusewitt, Donna F, DiGiovanni, John, Wood, Richard D

    “…DNA polymerase ζ (polζ) is critical for bypass of DNA damage and the associated mutagenesis, but also has unique functions in mammals. It is required for…”
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    Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs by Takata, Kei-ichi, Reh, Shelley, Tomida, Junya, Person, Maria D., Wood, Richard D.

    Published in Nature communications (04-09-2013)
    “…Mammalian HELQ is a 3′–5′ DNA helicase with strand displacement activity. Here we show that HELQ participates in a pathway of resistance to DNA interstrand…”
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  4. 4

    Defining the mutation signatures of DNA polymerase θ in cancer genomes by Hwang, Taejoo, Reh, Shelley, Dunbayev, Yerkin, Zhong, Yi, Takata, Yoko, Shen, Jianjun, McBride, Kevin M, Murnane, John P, Bhak, Jong, Lee, Semin, Wood, Richard D, Takata, Kei-Ichi

    Published in NAR cancer (01-09-2020)
    “…DNA polymerase theta (POLQ)-mediated end joining (TMEJ) is a distinct pathway for mediating DNA double-strand break (DSB) repair. TMEJ is required for the…”
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    Journal Article
  5. 5

    Conserved Overlapping Gene Arrangement, Restricted Expression, and Biochemical Activities of DNA Polymerase ν (POLN) by Takata, Kei-ichi, Tomida, Junya, Reh, Shelley, Swanhart, Lisa M., Takata, Minoru, Hukriede, Neil A., Wood, Richard D.

    Published in The Journal of biological chemistry (02-10-2015)
    “…DNA polymerase ν (POLN) is one of 16 DNA polymerases encoded in vertebrate genomes. It is important to determine its gene expression patterns, biological…”
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    Dual role for mammalian DNA polymerase [zeta] in maintaining genome stability and proliferative responses by Lange, Sabine S, Bedford, Ella, Reh, Shelley, Wittschieben, John P, Carbajal, Steve, Kusewitt, Donna F, DiGiovanni, John, Wood, Richard D

    “…DNA polymerase ... (pol...) is critical for bypass of DNA damage and the associated mutagenesis, but also has unique functions in mammals. It is required for…”
    Get full text
    Journal Article
  10. 10

    DNA polymerase ζ deficiency causes impaired wound healing and stress-induced skin pigmentation by Lange, Sabine S, Bhetawal, Sarita, Reh, Shelley, Powell, Katherine Leslie, Kusewitt, Donna F, Wood, Richard D

    Published in Life science alliance (01-06-2018)
    “…DNA polymerase ζ (pol ζ) is a specialized enzyme important for DNA damage tolerance, facilitating synthesis past lesions caused by radiation or chemical…”
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    Journal Article