Search Results - "Regulatory toxicology and pharmacology"

Integrating habits and practices data for soaps, cosmetics and air care products into an existing aggregate exposure model by Comiskey, D., Api, A.M., Barrett, C., Ellis, G., McNamara, C., O'Mahony, C., Robison, S.H., Rose, J., Safford, B., Smith, B., Tozer, S.

“…In order to accurately assess aggregate exposure to a fragrance material in consumers, data are needed on consumer habits and practices, as well as the…”
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Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products by Safford, B., Api, A.M., Barratt, C., Comiskey, D., Ellis, G., McNamara, C., O'Mahony, C., Robison, S., Rose, J., Smith, B., Tozer, S.

“…As part of a joint project between the Research Institute for Fragrance Materials (RIFM) and Creme Global, a Monte Carlo model (here named the Creme RIFM…”
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Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials by Api, Anne Marie, Basketter, David, Bridges, James, Cadby, Peter, Ellis, Graham, Gilmour, Nicola, Greim, Helmut, Griem, Peter, Kern, Petra, Khaiat, Alain, O'Brien, John, Rustemeyer, Thomas, Ryan, Cindy, Safford, Bob, Smith, Benjamin, Vey, Matthias, White, Ian R.

“…In 2008, a proposal for assessing the risk of induction of skin sensitization to fragrance materials Quantitative Risk Assessment 1 (QRA1) was published. This…”
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Arsenic exposure: A public health problem leading to several cancers by Palma-Lara, I., Martínez-Castillo, M., Quintana-Pérez, J.C., Arellano-Mendoza, M.G., Tamay-Cach, F., Valenzuela-Limón, O.L., García-Montalvo, E.A., Hernández-Zavala, A.

“…Arsenic, a metalloid and naturally occurring element, is one of the most abundant elements in the earth's crust. Water is contaminated by arsenic through…”
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Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products by Safford, B., Api, A.M., Barratt, C., Comiskey, D., Daly, E.J., Ellis, G., McNamara, C., O’Mahony, C., Robison, S., Smith, B., Thomas, R., Tozer, S.

“…•A probabilistic model to estimate aggregate exposure to fragrances is described.•The model can determine both systemic and dermal aggregate…”
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A strategy for structuring and reporting a read-across prediction of toxicity by Schultz, T.W., Amcoff, P., Berggren, E., Gautier, F., Klaric, M., Knight, D.J., Mahony, C., Schwarz, M., White, A., Cronin, M.T.D.

“…•A strategy to evaluate chemical category membership is presented.•Templates to assess similarity and characterise uncertainty are developed.•A strategy to…”
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Novel database for exposure to fragrance ingredients in cosmetics and personal care products by Comiskey, D., Api, A.M., Barratt, C., Daly, E.J., Ellis, G., McNamara, C., O’Mahony, C., Robison, S.H., Safford, B., Smith, B., Tozer, S.

“…•A database of cosmetics and personal care product use data for the analysis of fragrance ingredient exposure was developed.•The data and modelling methods…”
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Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review by Hadrup, Niels, Sharma, Anoop K., Loeschner, Katrin

“…Silver is used in different applications that result in contact with skin and mucosal surfaces (e.g., jewelry, wound dressings, or eye drops). Intact skin…”
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The safety of green tea and green tea extract consumption in adults – Results of a systematic review by Hu, Jiang, Webster, Donna, Cao, Joyce, Shao, Andrew

“…A systematic review of published toxicology and human intervention studies was performed to characterize potential hazards associated with consumption of green…”
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Regulatory landscape of dietary supplements and herbal medicines from a global perspective by Thakkar, Shraddha, Anklam, Elke, Xu, Alex, Ulberth, Franz, Li, Jing, Li, Bo, Hugas, Marta, Sarma, Nandakumara, Crerar, Scott, Swift, Sibyl, Hakamatsuka, Takashi, Curtui, Valeriu, Yan, William, Geng, Xingchao, Slikker, William, Tong, Weida

“…The number of Individuals that use dietary supplements and herbal medicine products are continuous to increase in many countries. The context of usage of a…”
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Health safety issues of synthetic food colorants by Amchova, Petra, Kotolova, Hana, Ruda-Kucerova, Jana

“…Increasing attention has been recently paid to the toxicity of additives used in food. The European Parliament and the Council published the REGULATION (EC)…”
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Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol by Schaller, Jean-Pierre, Keller, Daniela, Poget, Laurent, Pratte, Pascal, Kaelin, Etienne, McHugh, Damian, Cudazzo, Gianluca, Smart, Daniel, Tricker, Anthony R., Gautier, Lydia, Yerly, Michel, Reis Pires, Roger, Le Bouhellec, Soazig, Ghosh, David, Hofer, Iris, Garcia, Eva, Vanscheeuwijck, Patrick, Maeder, Serge

“…The chemical composition, in vitro genotoxicity, and cytotoxicity of the mainstream aerosol from the Tobacco Heating System 2.2 (THS2.2) were compared with…”
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Regulatory landscape of nanotechnology and nanoplastics from a global perspective by Allan, Jacqueline, Belz, Susanne, Hoeveler, Arnd, Hugas, Marta, Okuda, Haruhiro, Patri, Anil, Rauscher, Hubert, Silva, Primal, Slikker, William, Sokull-Kluettgen, Birgit, Tong, Weida, Anklam, Elke

“…Nanotechnology and more particularly nanotechnology-based products and materials have provided a huge potential for novel solutions to many of the current…”
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Distribution of fluoride contamination in drinking water resources and health risk assessment using geographic information system, northwest Iran by Yousefi, Mahmood, Ghalehaskar, Sahar, Asghari, Farzaneh Baghal, Ghaderpoury, Afshin, Dehghani, Mohammad Hadi, Ghaderpoori, Mansour, Mohammadi, Ali Akbar

“…This paper considers exposure to the concentration of fluoride in drinking water resources of Showt city in West Azerbaijan Province in, Iran, and its related…”
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In silico toxicology protocols by Myatt, Glenn J, Ahlberg, Ernst, Akahori, Yumi, Allen, David, Amberg, Alexander, Anger, Lennart T, Aptula, Aynur, Auerbach, Scott, Beilke, Lisa, Bellion, Phillip, Benigni, Romualdo, Bercu, Joel, Booth, Ewan D, Bower, Dave, Brigo, Alessandro, Burden, Natalie, Cammerer, Zoryana, Cronin, Mark T D, Cross, Kevin P, Custer, Laura, Dettwiler, Magdalena, Dobo, Krista, Ford, Kevin A, Fortin, Marie C, Gad-McDonald, Samantha E, Gellatly, Nichola, Gervais, Véronique, Glover, Kyle P, Glowienke, Susanne, Van Gompel, Jacky, Gutsell, Steve, Hardy, Barry, Harvey, James S, Hillegass, Jedd, Honma, Masamitsu, Hsieh, Jui-Hua, Hsu, Chia-Wen, Hughes, Kathy, Johnson, Candice, Jolly, Robert, Jones, David, Kemper, Ray, Kenyon, Michelle O, Kim, Marlene T, Kruhlak, Naomi L, Kulkarni, Sunil A, Kümmerer, Klaus, Leavitt, Penny, Majer, Bernhard, Masten, Scott, Miller, Scott, Moser, Janet, Mumtaz, Moiz, Muster, Wolfgang, Neilson, Louise, Oprea, Tudor I, Patlewicz, Grace, Paulino, Alexandre, Lo Piparo, Elena, Powley, Mark, Quigley, Donald P, Reddy, M Vijayaraj, Richarz, Andrea-Nicole, Ruiz, Patricia, Schilter, Benoit, Serafimova, Rositsa, Simpson, Wendy, Stavitskaya, Lidiya, Stidl, Reinhard, Suarez-Rodriguez, Diana, Szabo, David T, Teasdale, Andrew, Trejo-Martin, Alejandra, Valentin, Jean-Pierre, Vuorinen, Anna, Wall, Brian A, Watts, Pete, White, Angela T, Wichard, Joerg, Witt, Kristine L, Woolley, Adam, Woolley, David, Zwickl, Craig, Hasselgren, Catrin

“…The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It…”
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Azo dyes in clothing textiles can be cleaved into a series of mutagenic aromatic amines which are not regulated yet by Brüschweiler, Beat J., Merlot, Cédric

“…Azo dyes represent the by far most important class of textile dyes. Their biotransformation by various skin bacteria may release aromatic amines (AAs) which…”
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Regulatory aspects of nanotechnology in the agri/feed/food sector in EU and non-EU countries by Amenta, Valeria, Aschberger, Karin, Arena, Maria, Bouwmeester, Hans, Botelho Moniz, Filipa, Brandhoff, Puck, Gottardo, Stefania, Marvin, Hans J.P., Mech, Agnieszka, Quiros Pesudo, Laia, Rauscher, Hubert, Schoonjans, Reinhilde, Vettori, Maria Vittoria, Weigel, Stefan, Peters, Ruud J.

“…Nanotechnology has the potential to innovate the agricultural, feed and food sectors (hereinafter referred to as agri/feed/food). Applications that are…”
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Comparative assessment of nanomaterial definitions and safety evaluation considerations by Boverhof, Darrell R., Bramante, Christina M., Butala, John H., Clancy, Shaun F., Lafranconi, Mark, West, Jay, Gordon, Steve C.

“…Nanomaterials continue to bring promising advances to science and technology. In concert have come calls for increased regulatory oversight to ensure their…”
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An evaluation framework for new approach methodologies (NAMs) for human health safety assessment by Parish, Stanley T., Aschner, Michael, Casey, Warren, Corvaro, Marco, Embry, Michelle R., Fitzpatrick, Suzanne, Kidd, Darren, Kleinstreuer, Nicole C., Lima, Beatriz Silva, Settivari, Raja S., Wolf, Douglas C., Yamazaki, Daiju, Boobis, Alan

“…The need to develop new tools and increase capacity to test pharmaceuticals and other chemicals for potential adverse impacts on human health and the…”
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A review on arsenic carcinogenesis: Epidemiology, metabolism, genotoxicity and epigenetic changes by Zhou, Qing, Xi, Shuhua

“…Long-term exposure to arsenic (inorganic arsenic) is a world-wide environmental health concern. Arsenic is classified as the Group 1 human carcinogen by the…”
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