Search Results - "Regondi, Viola"

Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers by Di Modica, Martina, Regondi, Viola, Sandri, Marco, Iorio, Marilena V, Zanetti, Adriana, Tagliabue, Elda, Dr, Casalini, Patrizia, Triulzi, Tiziana

“…Abstract Exosomes-secreted microRNAs play an important role in metastatic spread. During this process breast cancer cells acquire the ability to transmigrate…”
Get full text

Infrared Spectroscopic Imaging Visualizes a Prognostic Extracellular Matrix-Related Signature in Breast Cancer by Tiwari, Saumya, Triulzi, Tiziana, Holton, Sarah, Regondi, Viola, Paolini, Biagio, Tagliabue, Elda, Bhargava, Rohit

“…Molecular analysis techniques such as gene expression analysis and proteomics have contributed greatly to our understanding of cancer heterogeneity. In prior…”
Get full text

HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy by Triulzi, Tiziana, Forte, Luca, Regondi, Viola, Di Modica, Martina, Ghirelli, Cristina, Carcangiu, Maria Luisa, Sfondrini, Lucia, Balsari, Andrea, Tagliabue, Elda

“…Through whole-transcriptome profiling of HER2+ breast carcinomas (BCs), we previously showed that those sensitive to trastuzumab are addicted to this…”
Get full text

Gut Microbiota Condition the Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer by Di Modica, Martina, Gargari, Giorgio, Regondi, Viola, Bonizzi, Arianna, Arioli, Stefania, Belmonte, Beatrice, De Cecco, Loris, Fasano, Elena, Bianchi, Francesca, Bertolotti, Alessia, Tripodo, Claudio, Villani, Laura, Corsi, Fabio, Guglielmetti, Simone, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda

“…Emerging evidence indicates that gut microbiota affect the response to anticancer therapies by modulating the host immune system. In this study, we…”
Get full text

Combined targeting of EGFR and HER2 against prostate cancer stem cells by Rossini, Anna, Giussani, Marta, Ripamonti, Francesca, Aiello, Piera, Regondi, Viola, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda

“…Progression of prostate cancer has been associated with EGFR and HER2 activation and to tumor-initiating cells contribution toward chemotherapy resistance. We…”
Get full text

Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit by Triulzi, Tiziana, Regondi, Viola, De Cecco, Loris, Cappelletti, Maria Rosa, Di Modica, Martina, Paolini, Biagio, Lollini, Pier Luigi, Di Cosimo, Serena, Sfondrini, Lucia, Generali, Daniele, Tagliabue, Elda

“…Background Optimising the selection of HER2-targeted regimens by identifying subsets of HER2-positive breast cancer (BC) patients who need more or less therapy…”
Get full text

SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness by Rybinska, Ilona, Mangano, Nunzia, Romero-Cordoba, Sandra L, Regondi, Viola, Ciravolo, Valentina, De Cecco, Loris, Maffioli, Elisa, Paolini, Biagio, Bianchi, Francesca, Sfondrini, Lucia, Tedeschi, Gabriella, Agresti, Roberto, Tagliabue, Elda, Triulzi, Tiziana

“…Triple negative breast cancers (TNBC) are characterized by a poor prognosis and a lack of targeted treatments. Their progression depends on tumor cell…”
Get full text

Abstract P4-10-32: Commensal gut microbiota influences efficacy of trastuzumab in patients with HER2-positive breast carcinoma by Tagliabue, Elda, Modica, Martina Di, Gargari, Giorgio, Regondi, Viola, Bonizzi, Arianna, Arioli, Stefania, Corsi, Fabio, Guglielmetti, Simone, Triulzi, Tiziana

“…Abstract Although the clinical benefit of trastuzumab for the management of HER2-positive breast carcinomas (BCs) has been largely demonstrated, many women,…”
Get full text

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition by Di Modica, Martina, Sfondrini, Lucia, Regondi, Viola, Varchetta, Stefania, Oliviero, Barbara, Mariani, Gabriella, Bianchi, Giulia Valeria, Generali, Daniele, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda

“…Recent clinical data indicate a synergistic therapeutic effect between trastuzumab and taxanes in neoadjuvantly treated HER2-positive breast cancer (BC)…”
Get full text

Abstract 4959: The gut microbiota contributes to the effectiveness of HER2-targeted therapy by Modica, Martina Di, Regondi, Viola, Gargari, Giorgio, Bonizzi, Arianna, Arioli, Stefania, Belmonte, Beatrice, Tripodo, Claudio, Guglielmetti, Simone, Corsi, Fabio, Triulzi, Tiziana, Tagliabue, Elda

“…Abstract Recently, the composition of the gut microbiota, due to its influence on host immune system, has been linked to the effectiveness of chemotherapy and…”
Get full text

Abstract 6838: Adipose tissue features in breast cancer patients: Impact and modifications induced by tumor according to body mass index by Romero-Cordoba, Sandra, Agresti, Roberto, Regondi, Viola, Trecate, Giovanna, Bianchi, Francesca, Sfondrini, Lucia, Pupa, Serenella M., Tagliabue, Elda, Triulzi, Tiziana

“…Abstract Adipose tissue (AT) is emerging as a contributing factor to cancer development and progression, especially in obesity. However, the mechanisms…”
Get full text

Abstract 748: Targeting the crosstalk between tumor cells and adipocytes to block breast cancer progression by Triulzi, Tiziana, Ciravolo, Valentina, Regondi, Viola, Di Modica, Martina, Chiodoni, Claudia, Tagliabue, Elda

“…Abstract It is now well-established that the local microenvironment of an emerging tumor plays a vital role in various steps of tumorigenesis. Stromal cells,…”
Get full text

HER2 mRNA Levels, Estrogen Receptor Activity and Susceptibility to Trastuzumab in Primary Breast Cancer by Triulzi, Tiziana, Regondi, Viola, Venturelli, Elisabetta, Gasparini, Patrizia, Ghirelli, Cristina, Groppelli, Jessica, Di Modica, Martina, Bianchi, Francesca, De Cecco, Loris, Sfondrini, Lucia, Tagliabue, Elda

“…While the results thus far demonstrate the clinical benefit of trastuzumab in breast cancer (BC), some patients do not respond to this drug. HER2 mRNA, alone…”
Get full text

Abstract 5207: miR-491 and miR-218: Two possible tools to reduce FOXP3 expression in breast carcinomas by Modica, Martina D., Triulzi, Tiziana, Regondi, Viola, Iorio, Marilena V., Balsari, Andrea, Tagliabue, Elda, Casalini, Patrizia

“…Abstract The Forkhead box P3 (FOXP3) gene is a member of the forkhead/winged-helix family of transcription factors implicated in the regulation of immune…”
Get full text

Abstract 5015: Tumor dependence on HER2 signaling as a player in immune infiltration required for trastuzumab activity by Triulzi, Tiziana, Regondi, Viola, De Cecco, Loris, Ghedini, Gaia, Carcangiu, Maria Luisa, Pupa, Serenella M., Tagliabue, Elda

“…Abstract The identification of a robust clinical or molecular predictor of trastuzumab benefit has proven challenging. Recent clinical studies have shown that…”
Get full text

Abstract P4-15-06: Correlation between ERBB2 mRNA levels, HER2-dependence and susceptibility to trastuzumab in human breast cancer by Tagliabue, Elda, Regondi, Viola, De Cecco, Loris, Pupa, Serenella M, Campiglio, Manuela, Carcangiu, Maria Luisa, Ménard, Sylvie, Triulzi, Tiziana

“…Abstract While results thus far demonstrate the clinical benefit of trastuzumab in breast cancer, some patients do not respond to this reagent. Identifying a…”
Get full text

Maspin influences response to doxorubicin by changing the tumor microenvironment organization by Triulzi, Tiziana, Ratti, Manuela, Tortoreto, Monica, Ghirelli, Cristina, Aiello, Piera, Regondi, Viola, Di Modica, Martina, Cominetti, Denis, Carcangiu, Maria L., Moliterni, Angela, Balsari, Andrea, Casalini, Patrizia, Tagliabue, Elda

“…Altered degradation and deposition of extracellular matrix are hallmarks of tumor progression and response to therapy. From a microarray supervised analysis on…”
Get full text

Chemotherapy can enhance trastuzumab-mediated ADCC by Tiziana, Triulzi, Lucia, Sfondrini, Stefania, Varchetta, Viola, Regondi, Marianna, Sasso, Patrizia, Casalini, Andrea, Balsari, Giulia, Bianchi, Gabriella, Mariani, Elda, Tagliabue

“…Abstract only…”
Get full text