Search Results - "Regla, Ignacio"

Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats by Quiñonez-Bastidas, Geovanna Nallely, Osuna-Martínez, Ulises, Reda-Licea, Ana Laura, López-Ortíz, Manuel, Regla, Ignacio, Navarrete, Andrés

“…In the present study the interaction of cannabinoid, PhAR-DBH-Me [( , )-18-((1 ,4…”
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Phenylpropanoid glycoside analogues: enzymatic synthesis, antioxidant activity and theoretical study of their free radical scavenger mechanism by López-Munguía, Agustín, Hernández-Romero, Yanet, Pedraza-Chaverri, José, Miranda-Molina, Alfonso, Regla, Ignacio, Martínez, Ana, Castillo, Edmundo

“…Phenylpropanoid glycosides (PPGs) are natural compounds present in several medicinal plants that have high antioxidant power and diverse biological activities…”
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Characterization of hypotensive and vasorelaxant effects of PHAR-DBH-Me a new cannabinoid receptor agonist by López-Canales, Oscar Alberto, Pavón, Natalia, Ubaldo-Reyes, Laura Matilde, Juárez-Oropeza, Marco Antonio, Torres-Durán, Patricia Victoria, Regla, Ignacio, Paredes-Carbajal, María Cristina

“…The effect of PHAR-DBH-Me, a cannabinoid receptor agonist, on different cardiovascular responses in adult male rats was analyzed. The blood pressure was…”
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Multicomponent synthesis of some new (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamates and their in vitro anti-proliferative activity against CaSki, MDA-MB-231 and SK-Lu-1 tumour cells as apoptosis inducing agents without necrosis by Laskar, Sujay, Sánchez-Sánchez, Luis, López-Ortiz, Manuel, López-Muñoz, Hugo, Escobar-Sánchez, María L., Sánchez, Arturo T., Regla, Ignacio

“…Identification of a new class of antitumor agent capable to induce apoptosis without triggering necrotic cell death event is challenging. The present…”
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2,4-Bis(fluorocarbon)-substituted phenols for high yield Newman–Kwart rearrangement reactions by Mondragón, Alexander, Monsalvo, Iván, Regla, Ignacio, Castillo, Ivan

“…The O-thiocarbamates of 2,4-disubstituted phenols with fluorinated groups undergo facile and high yielding Newman–Kwart thermal rearrangement reactions to the…”
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Characterization of hypotensive and vasorelaxant effects of PHAR-DBH-Me a new cannabinoid receptor agonist by Lopez-Canales, Oscar Alberto, Pavon, Natalia, Ubaldo-Reyes, Laura Matilde, Juarez-Oropeza, Marco Antonio, Torres-Duran, Patricia Victoria, Regla, Ignacio, Paredes-Carbajal, Maria Cristina

“…The effect of PHAR-DBH-Me, a cannabinoid receptor agonist, on different cardiovascular responses in adult male rats was analyzed. The blood pressure was…”
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Application of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane derivatives in asymmetric organocatalysis: the Biginelli reaction by González-Olvera, Rodrigo, Demare, Patricia, Regla, Ignacio, Juaristi, Eusebio

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Synthesis of Two Local Anesthetics from Toluene: An Organic Multistep Synthesis in a Project-Oriented Laboratory Course by Demare, Patricia, Regla, Ignacio

“…This article describes one of the projects in the advanced undergraduate organic chemistry laboratory course concerning the synthesis of two local anesthetic…”
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Evolutionary, Functional and Structural Studies of the ALDH27 Enzymes by MUÑOZ‐CLARES, ROSARIO A., JUÁREZ‐VÁZQUEZ, ANA L., CARDONACARDONA, YUDY V., GONZÁLEZ‐SEGURA, LILIAN, RIVEROS‐ROSAS, HÉCTOR, REGLA, IGNACIO

“…The ALDH27 family of the aldehyde dehydrogenase superfamily comprises bacterial enzymes poorly studied so far in spite of seemingly being widely distributed,…”
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The critical role of the aldehyde dehydrogenase PauC in spermine, spermidine, and diaminopropane toxicity in Pseudomonas aeruginosa: Its possible use as a drug target by Cardona‐Cardona, Yudy V., Regla, Ignacio, Juárez‐Díaz, Javier Andrés, Carrillo‐Campos, Javier, López‐Ortiz, Manuel, Aguilera‐Cruz, Alejandro, Mújica‐Jiménez, Carlos, Muñoz‐Clares, Rosario A.

“…The opportunistic human pathogen Pseudomonas aeruginosa exhibits great resistance to antibiotics; so, new therapeutic agents are urgently needed. Since…”
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Identification of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamate-nitrostyrene hybrid as potent antiproliferative and apoptotic inducing agent against cervical cancer cell lines by Laskar, Sujay, Sánchez-Sánchez, Luis, Flores, Sebastián M., López-Muñoz, Hugo, Escobar-Sánchez, María L., López-Ortiz, Manuel, Hernández-Rodríguez, Marcos, Regla, Ignacio

“…The present study seeks to describe the design and synthesis of six new Michael adducts of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-dithiocarbamate with…”
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Directed ortho-metalation versus reductive amination in the preparation of polytopic, highly substituted, and sterically congested amine-S-arylthiocarbamates as thiophenol precursors by Mondragón, Alexander, Monsalvo, Iván, Regla, Ignacio, Flores-Alamo, Marcos, Castillo, Ivan

“…The synthesis of polydentate amine-S-arythiocarbamates was tested by directed ortho-lithiation of 2,4-disubstituted thiophenols, or the corresponding O- and…”
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Preclinical safety evaluation of amphotericin A21: A novel antifungal by Ortega‐Blake, Ivan, Fernández‐Zertuche, Mario, Regla, Ignacio, Sánchez‐Peña, Walfred, Gómez‐Solis, Antonieta, Jaimes‐Chavez, Paola, Galván‐Hernández, Arturo, Tovar‐Garduño, Erika, Rodríguez‐Fragoso, Lourdes

“…Safety studies are essential in drug development. This study evaluates the safety of Amphotericin A21 (AmB‐A21), a derivative of amphotericin B with antifungal…”
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Sustainable Process for Sparteine Sulfate Preparation by Regla, Ignacio, López-Ortiz, Manuel, Jiménez, Otoniel, Hernández-Ortega, Simón, Ramírez-Betancourt, Astrid, Bermúdez-Torres, Kalina

“…(−)-Sparteine sulfate is a stable salt of the quinolizidine chiral diamine alkaloid (−)-sparteine. This compound, in addition to presenting various biological…”
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Evaluation of safety and efficacy antifungal of an amide derivative of amphotericin B as scaling product on in vitro models (844.12) by Rodriguez ‐Lopez, Anahí, Ortega, Ivan, Fernandez‐Zertuche, Mario, Regla, Ignacio, Reyes‐Esparza, Jorge, Rodríguez‐Fragoso, Lourdes

“…To evaluate the efficacy and safety of amide derivative of amphotericin B, as scaling product at in vitro experimental assays. Amphotericin B (AmB) has been…”
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Evaluation of the antitumour activity of Rinvanil and Phenylacetylrinvanil on the cervical cancer tumour cell lines HeLa, CaSKi and ViBo by Sánchez-Sánchez, Luis, Alvarado-Sansininea, Jesús J., Escobar, María L., López-Muñoz, Hugo, Hernández-Vázquez, José M.V., Monsalvo-Montiel, Iván, Demare, Patricia, Regla, Ignacio, Weiss-Steider, Benny

“…Capsaicin is a potent inducer of apoptosis in tumourreceptor potential vanilloid 1 (TRPV1). The present study determined the IC50 and cytotoxic and apoptotic…”
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Copper(II) complexes of piperazine-derived tetradentate ligands and their chiral diazabicyclic analogues for catalytic phenol oxidative C–C coupling by Castillo, Ivan, Pérez, Viridiana, Monsalvo, Iván, Demare, P., Regla, Ignacio

“…Reaction of the chiral ligands (1S,4S)-2,5-bis(6-methylpyridyl)-diazabicyclo[2.2.1]heptane (L1) and…”
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Copper Versus Thioether-Centered Oxidation: Mechanistic Insights into the Non-Innocent Redox Behavior of Tripodal Benzimidazolylaminothioether Ligands by Martínez-Alanis, Paulina R., Sánchez Eguía, Brenda N., Ugalde-Saldívar, Víctor M., Regla, Ignacio, Demare, Patricia, Aullón, Gabriel, Castillo, Ivan

“…A series of Cu+ complexes with ligands that feature varying numbers of benzimidazole/thioether donors and methylene or ethylene linkers between the central…”
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Multigram Scale Synthesis of A21, A New Antibiotic Equally Effective and Less Toxic than Amphotericin B by Flores-Romero, José David, Rodríguez-Lozada, Josué, López-Ortiz, Manuel, Magaña, Ricardo, Ortega-Blake, Iván, Regla, Ignacio, Fernández-Zertuche, Mario

“…A21 (2) is a new polyene macrolide Amphotericin B amide antibiotic derived from amphotericin B AmB (1), which has been tested extensively on preclinical trials…”
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Effects of Ranolazine on Vasomotor Responses of Rat Aortic Rings by Paredes-Carbajal, Ma. Cristina, Monsalvo, Ivan, Hernández-Díaz, Carlos, Regla, Ignacio, Demare, Patricia, Mascher, Dieter

“…Background and Aims Ranolazine is a piperazine derivative that was approved in 2006 for the treatment of chronic stable angina. Compared with first-line drugs…”
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