Search Results - "Reginauld, Shawn H."
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Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP
Published in JACC. Heart failure (01-10-2019)“…This study investigated the differential regulation of circulating atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) in patients with acute…”
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Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation
Published in International journal of molecular sciences (10-05-2023)“…The natriuretic peptide system (NPS) and renin-angiotensin-aldosterone system (RAAS) function oppositely at multiple levels. While it has long been suspected…”
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Reply: The Role of miRNAs and lncRNAs in ANP Production Downregulation in Heart Failure
Published in JACC. Heart failure (01-01-2020)Get full text
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Prognostic Value of Urinary and Plasma C-Type Natriuretic Peptide in Acute Decompensated Heart Failure
Published in JACC. Heart failure (01-09-2021)“…This study sought to characterize urinary and plasma C-type natriuretic peptide (CNP) in acute decompensated heart failure (ADHF) to define their relationship…”
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Abstract 13473: Impaired Atrial Natriuretic Peptide Potency in Human Acute Decompensated Heart Failure and Therapeutic Potential of a Novel Designer Peptide (MANP) Using an Innovative Ex-Vivo Precision Medicine Assay
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionAtrial natriuretic peptide (ANP) is the most potent endogenous activator of the guanylyl cyclase A receptor (GC-A) mediating cardiorenal protective…”
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Abstract 15838: Atrial Natriuretic Peptide Compensatory Response is Impaired in Human Acute Decompensated Heart Failure
Published in Circulation (New York, N.Y.) (17-11-2020)“…Atrial and B-type natriuretic peptides (ANP and BNP) are cardiac hormones secreted as compensatory measures to preserve cardiorenal homeostasis. Treating heart…”
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Cardiac Natriuretic Peptide And Cgmp Impairment In Human Decompensated Heart Failure: Employing A Novel Ex Vivo Natriuretic Peptide/GC-A/cGMP Potency Assay To Evaluate Natriuretic Peptide Therapeutic Capacity
Published in Journal of cardiac failure (01-04-2022)“…In acute decompensated heart failure (ADHF), atrial and b-type natriuretic peptides (ANP and BNP) are elevated as a compensatory mechanism to maintain…”
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Prognostic Implications of Urinary and Plasma C-type Natriuretic Peptide in Human Acute Decompensated Heart Failure
Published in Journal of cardiac failure (01-10-2020)“…C-type natriuretic peptide (CNP) is a cardiorenal-derived hormone that possesses potent anti-fibrotic, anti-hypertrophic, anti-apoptotic and cardiac unloading…”
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Abstract 14706: Reconsidering Natriuretic Peptide Targeted Therapies in Acute Decompensated Heart Failure: Addressing a Relative Deficient State of Circulating ANP
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionThe endocrine heart releases atrial and b-type natriuretic peptides (ANP and BNP) which serve as blood pressure and body fluid regulating hormones…”
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