Search Results - "Regina Martinez, Glaucia"

Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: Antioxidants, lipid peroxidation and DNA damage by Alves de Almeida, Eduardo, Celso Dias Bainy, Afonso, Paula de Melo Loureiro, Ana, Regina Martinez, Glaucia, Miyamoto, Sayuri, Onuki, Janice, Fujita Barbosa, Lívea, Carrião Machado Garcia, Camila, Manso Prado, Fernanda, Eliza Ronsein, Graziella, Alexandre Sigolo, Carlos, Barbosa Brochini, Cláudia, Maria Gracioso Martins, Ana, Helena Gennari de Medeiros, Marisa, Di Mascio, Paolo

“…Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative…”
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Selective Cytotoxicity of 1,3,4-Thiadiazolium Mesoionic Derivatives on Hepatocarcinoma Cells (HepG2) by Gozzi, Gustavo Jabor, Pires, Amanda do Rocio Andrade, Valdameri, Glaucio, Rocha, Maria Eliane Merlin, Martinez, Glaucia Regina, Noleto, Guilhermina Rodrigues, Acco, Alexandra, Alves de Souza, Carlos Eduardo, Echevarria, Aurea, Moretto Dos Reis, Camilla, Di Pietro, Attilio, Suter Correia Cadena, Sílvia Maria

“…In this work, we evaluated the cytotoxicity of mesoionic 4-phenyl-5-(2-Y, 4-X or 4-X-cinnamoyl)-1,3,4-thiadiazolium-2-phenylamine chloride derivatives (MI-J:…”
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Effects of the melanin precursor 5,6-dihydroxy-indole-2-carboxylic acid (DHICA) on DNA damage and repair in the presence of reactive oxygen species by Pellosi, Maria Carolina, Suzukawa, Andréia Akemi, Scalfo, Alexsandra Cristina, Di Mascio, Paolo, Martins Pereira, Carolina Parga, de Souza Pinto, Nadja Cristhina, de Luna Martins, Daniela, Martinez, Glaucia Regina

“…•DHICA causes single strand breaks in plasmid DNA in the absence of light radiation.•DHICA oxidized by 1O2 loses the capacity to induce DNA damage.•DHICA…”
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Antioxidant effect of 1,3,4-thiadiazolium mesoionic derivatives on isolated mitochondria by Andrade Pires, Amanda do Rocio, Jabor Gozzi, Gustavo, Rodrigues Noleto, Guilhermina, Echevarria, Aurea, Moretto Reis, Camilla, Merlin Rocha, Maria Eliane, Regina Martinez, Glaucia, Correia Cadena, Silvia Maria Suter

“…Mesoionic compounds have shown antitumor and citotoxic activity against different tumor cells lines, which has been attributed to their physical and chemical…”
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Plasmid DNA damage induced by singlet molecular oxygen released from the naphthalene endoperoxide DHPNO2 and photoactivated methylene blue by Berra, Carolina Maria, Menck, Carlos Frederico Martins, Martinez, Glaucia Regina, Oliveira, Carla Santos de, Baptista, Maurício da Silva, Di Mascio, Paolo

“…To investigate oxidative lesions and strand breaks induction by singlet molecular oxygen (¹O2), supercoiled-DNA plasmid was treated with thermo-dissociated…”
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Structure and intracellular antioxidant activity of pectic polysaccharide from acerola (Malpighia emarginata) by Klosterhoff, Rafael Roberto, Bark, Juliana Müller, Glänzel, Nícolas Manzke, Iacomini, Marcello, Martinez, Gláucia Regina, Winnischofer, Sheila M.B., Cordeiro, Lucimara M.C.

“…Malpighia emarginata is a tropical fruit plant, found naturally in the Caribbean islands and South America that produces an edible fruit known as acerola or…”
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Pectin from Brassica oleracea var. italica triggers immunomodulating effects in vivo by Busato, Bianca, de Almeida Abreu, Elaine Cristina, de Oliveira Petkowicz, Carmen Lucia, Martinez, Glaucia Regina, Rodrigues Noleto, Guilhermina

“…The immunomodulatory ability of pectins is related with structural features such as the degree of methyl-esterification and branching, as well as the molecular…”
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Unveiling novel targets in melanoma under melanogenesis stimulation and photodynamic therapy by redox proteomics by Mazepa, Ester, Cunha, Elizabeth Sousa, Valerio, Hellen Paula, Di Mascio, Paolo, Batista, Michel, Marchini, Fabricio Klerynton, Meira, Willian Vanderlei, Noleto, Guilhermina Rodrigues, Winnischofer, Sheila Maria Brochado, Martinez, Glaucia Regina

“…Melanogenesis-stimulated B16-F10 cells enter in a quiescent state, present inhibited mitochondrial respiration and increased reactive oxygen species levels…”
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Effects of redox modulation on quiescin/sulfhydryl oxidase activity of melanoma cells by Mazepa, Ester, Furlanetto, Ana Luiza Dorigan de Matos, Brum, Hulyana, Nakao, Lia Sumie, Martinez, Pierina Alexandra, Cadena, Silvia Maria Suter Correia, Rocha, Maria Eliane Merlin, Cunha, Elizabeth Sousa, Martinez, Glaucia Regina

“…Secreted quiescin/sulfhydryl oxidase (QSOX) is overexpressed in many tumor cell lines, including melanoma, and is usually associated with a pro-invasive…”
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High Melanin Content in Melanoma Cells Contributes to Enhanced DNA Damage after Rose Bengal Photosensitization by Kalegari, Paloma, Leme, Daniela Morais, Disner, Geonildo Rodrigo, Cestari, Marta Margarete, Lima Bellan, Daniel, Meira, Willian Vanderlei, Mazepa, Ester, Martinez, Glaucia Regina

“…Melanoma is a type of tumor that originates from melanocytes. Irradiation of melanin with UVA and visible light can produce reactive oxygen species (ROS) such…”
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Modified pectin from Theobroma cacao induces potent pro-inflammatory activity in murine peritoneal macrophage by Amorim, Juliana C., Vriesmann, Lucia Cristina, Petkowicz, Carmen L.O., Martinez, Glaucia Regina, Noleto, Guilhermina R.

“…⿢Studied pectins modulate macrophages.⿢They presented distinct pattern on murine peritoneal macrophage activation.⿢Acetylated pectin (OP) from cacao pod husks…”
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Mitochondrial bioenergetics and enzymatic antioxidant defense differ in Paraná pine cell lines with contrasting embryogenic potential by Dorigan de Matos Furlanetto, Ana Luiza, Kaziuk, Fernando Diego, Martinez, Glaucia Regina, Donatti, Lucelia, Merlin Rocha, Maria Eliane, Dos Santos, André Luis Wendt, Floh, Eny Iochevet Segal, Cadena, Silvia Maria Suter Correia

“…is classified as a critically endangered species by the International Union for Conservation of Nature. This threat is worsened by the inefficiency of methods…”
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The metabolic response of Araucaria angustifolia embryogenic cells to heat stress is associated with their maturation potential by Kaziuk, Fernando Diego, Furlanetto, Ana Luiza Dorigan de Matos, Dos Santos, André Luis Wendt, Floh, Eny Iochevet Senegal, Donatti, Lucelia, Merlin Rocha, Maria Eliane, Fortes, Fabiane, Martinez, Glaucia Regina, Cadena, Silvia Maria Suter Correia

“…Araucaria angustifolia is a critically endangered species and its distribution can be affected by an increase in temperature. In this study, we evaluated the…”
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Melanogenesis inhibits respiration in B16-F10 melanoma cells whereas enhances mitochondrial cell content by Meira, Willian Vanderlei, Heinrich, Tassiele Andréa, Cadena, Silvia Maria Suter Correia, Martinez, Glaucia Regina

“…Melanoma is a rare and aggressive skin tumor; the survival of patients diagnosed late is fairly low. This high mortality rate is due to the characteristics of…”
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Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions by Cunha - de Padua, Monique Meyenberg, Suter Correia Cadena, Silvia Maria, de Oliveira Petkowicz, Carmen Lucia, Martinez, Glaucia Regina, Merlin Rocha, Maria Eliane, Mercê, Ana Lucia Ramalho, Noleto, Guilhermina Rodrigues

“…•Galactomannan from S. amazonicum (SAGM) was modified by acidic hydrolysis (MSAGM).•SAGM and MSAGM were complexed with oxovanadium resulting in SAGM:VO and…”
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Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells by Farias, Carolina Lane Alves, Martinez, Glaucia Regina, Cadena, Silvia Maria Suter Correia, Mercê, Ana Lucia Ramalho, de Oliveira Petkowicz, Carmen Lucia, Noleto, Guilhermina Rodrigues

“…The aim of this study was to investigate the effects of xyloglucan extracted from Copaifera langsdorffii seeds (XGC) and its complex with oxovanadium (XGC:VO)…”
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The alternatively spliced RECK transcript variant 3 is a predictor of poor survival for melanoma patients being upregulated in aggressive cell lines and modulating MMP gene expression in vitro by Jacomasso, Thiago, Ribas, Hennrique Taborda, Trombetta-Lima, Marina, Silberspitz Konig, Michelle, Trindade, Edvaldo da Silva, Martinez, Glaucia Regina, Sogayar, Mari Cleide, Winnischofer, Sheila Maria Brochado

“…The reversion-inducing cysteine-rich protein with kazal motifs (RECK) gene was described as a tumor suppressor gene two decades ago. Recently, novel…”
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Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells by Cunha de Padua, Monique Meyenberg, Suter Correia Cadena, Silvia Maria, de Oliveira Petkowicz, Carmen Lucia, Martinez, Glaucia Regina, Rodrigues Noleto, Guilhermina

“…This study evaluated the effects of native galactomannan from Schizolobium amazonicum seeds and its sulfated forms on certain metabolic parameters of HepG2…”
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Simvastatin rises reactive oxygen species levels and induces senescence in human melanoma cells by activation of p53/p21 pathway by Guterres, Fernanda Augusta de Lima Barbosa, Martinez, Glaucia Regina, Rocha, Maria Eliane Merlin, Winnischofer, Sheila Maria Brochado

“…Recent studies demonstrated that simvastatin has antitumor properties in several types of cancer cells, mainly by inducing apoptosis and inhibiting growth. The…”
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Cytotoxic effects of 4′-hydroxychalcone on human neuroblastoma cells (SH-SY5Y) by de Moura Escobar, Stephane Janaina, Simone, Martin, Martin, Nathan, de Oliveira Ribeiro, Ciro Alberto, Martinez, Glaucia Regina, Winnischofer, Sheila Maria Brochado, Witting, Paul Kenneth, Rocha, Maria Eliane Merlin

“…Neuroblastoma is an aggressive form of cancer with high mortality. Hydroxychalcones have received considerable attention because of their cytotoxic activities…”
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