Search Results - "Regina, K."

Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells by Sun, Yang, Hu, Lu, Tao, Zhipeng, Jarugumilli, Gopala K., Erb, Hannah, Singh, Alka, Li, Qi, Cotton, Jennifer L., Greninger, Patricia, Egan, Regina K., Tony Ip, Y., Benes, Cyril H., Che, Jianwei, Mao, Junhao, Wu, Xu

“…Targeting TEAD autopalmitoylation has been proposed as a therapeutic approach for YAP-dependent cancers. Here we show that TEAD palmitoylation inhibitor…”
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Greenhouse gas fluxes in varying soils types under conventional and no-tillage practices by Regina, K., Alakukku, L.

“…Consideration of the environmental effects of the no-tillage practice should be made on the basis of its effects on both carbon and nitrogen cycles. There is a…”
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KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition by Misale, Sandra, Fatherree, Jackson P, Cortez, Eliane, Li, Chendi, Bilton, Samantha, Timonina, Daria, Myers, David T, Lee, Dana, Gomez-Caraballo, Maria, Greenberg, Max, Nangia, Varuna, Greninger, Patricia, Egan, Regina K, McClanaghan, Joseph, Stein, Giovanna T, Murchie, Ellen, Zarrinkar, Patrick P, Janes, Matthew R, Li, Lian-Sheng, Liu, Yi, Hata, Aaron N, Benes, Cyril H

“…KRAS-mutant lung cancers have been recalcitrant to treatments including those targeting the MAPK pathway. Covalent inhibitors of KRAS p.G12C allele allow for…”
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Interspecific interactions within a vector-borne complex are influenced by a co-occurring pathosystem by Cruzado-Gutiérrez, Regina K., Sadeghi, Rohollah, Prager, Sean M., Casteel, Clare L., Parker, Jessica, Wenninger, Erik J., Price, William J., Bosque-Pérez, Nilsa A., Karasev, Alexander V., Rashed, Arash

“…Potato virus Y (PVY) and zebra chip (ZC) disease are major threats to solanaceous crop production in North America. PVY can be spread by aphid vectors and…”
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BRAF and AXL oncogenes drive RIPK3 expression loss in cancer by Najafov, Ayaz, Zervantonakis, Ioannis K, Mookhtiar, Adnan K, Greninger, Patricia, March, Ryan J, Egan, Regina K, Luu, Hoang Son, Stover, Daniel G, Matulonis, Ursula A, Benes, Cyril H, Yuan, Junying

“…Necroptosis is a lytic programmed cell death mediated by the RIPK1-RIPK3-MLKL pathway. The loss of Receptor-interacting serine/threonine-protein kinase 3…”
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Comparative Analysis of Resident Space Object (RSO) Detection Methods by Suthakar, Vithurshan, Sanvido, Aiden Alexander, Qashoa, Randa, Lee, Regina S K

“…In recent years, there has been a significant increase in satellite launches, resulting in a proliferation of satellites in our near-Earth space environment…”
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Sarcopenia risk and associated factors among Chinese community-dwelling older adults living alone by Cheng, Li, Sit, Janet W. H., Chan, Helen Y. L., Choi, Kai Chow, Cheung, Regina K. Y., Wong, Martin M. H., Li, Francis Y. K., Lee, Tin Yan, Fung, Elina S. M., Tai, Keen Man, So, Winnie K. W.

“…Sarcopenia, defined as a progressive loss of muscle mass and reduced muscle strength and functional capacity, is common among older adults. This study aimed to…”
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ST6GAL1 is associated with poor response to chemoradiation in rectal cancer by Smithson, Mary, Diffalha, Sameer Al, Irwin, Regina K., Williams, Gregory, McLeod, M. Chandler, Somasundaram, Vivek, Bellis, Susan L., Hardiman, Karin M.

“…Colorectal cancer is the third most common cause of cancer death. Rectal cancer makes up a third of all colorectal cases. Treatment for locally advanced rectal…”
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A Dual-Purpose Camera for Attitude Determination and Resident Space Object Detection on a Stratospheric Balloon by Chianelli, Gabriel, Kunalakantha, Perushan, Myhre, Marissa, Lee, Regina S K

“…Space systems play an integral role in every facet of our daily lives, including national security, communications, and resource management. Therefore, it is…”
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Stratospheric Night Sky Imaging Payload for Space Situational Awareness (SSA) by Kunalakantha, Perushan, Baires, Andrea Vallecillo, Dave, Siddharth, Clark, Ryan, Chianelli, Gabriel, Lee, Regina S K

“…Space situational awareness (SSA) refers to collecting, analyzing, and keeping track of detailed knowledge of resident space objects (RSOs) in the space…”
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Special Issue "Pediatric Viral Infection Long-Term Consequences" by Rowe, Regina K, Mohr, Emma L

“…This Special Issue was focused on advancing our understanding of the long-term consequences of pediatric viral infections [...]…”
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A landscape of response to drug combinations in non-small cell lung cancer by Nair, Nishanth Ulhas, Greninger, Patricia, Zhang, Xiaohu, Friedman, Adam A., Amzallag, Arnaud, Cortez, Eliane, Sahu, Avinash Das, Lee, Joo Sang, Dastur, Anahita, Egan, Regina K., Murchie, Ellen, Ceribelli, Michele, Crowther, Giovanna S., Beck, Erin, McClanaghan, Joseph, Klump-Thomas, Carleen, Boisvert, Jessica L., Damon, Leah J., Wilson, Kelli M., Ho, Jeffrey, Tam, Angela, McKnight, Crystal, Michael, Sam, Itkin, Zina, Garnett, Mathew J., Engelman, Jeffrey A., Haber, Daniel A., Thomas, Craig J., Ruppin, Eytan, Benes, Cyril H.

“…Combination of anti-cancer drugs is broadly seen as way to overcome the often-limited efficacy of single agents. The design and testing of combinations are…”
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Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin by Yoo, Byunghee, Greninger, Patricia, Stein, Giovanna T, Egan, Regina K, McClanaghan, Joseph, Moore, Anna, Benes, Cyril H, Medarova, Zdravka

“…Since microRNAs (miRNAs, miRs) have been implicated in oncogenesis, many of them have been identified as therapeutic targets. Previously we have demonstrated…”
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Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer by Smithson, Mary, Irwin, Regina K., Williams, Gregory, McLeod, M. Chandler, Choi, E. Karen, Ganguly, Anutosh, Pepple, Ashley, Cho, Clifford S., Willey, Christopher D., Leopold, Judith, Hardiman, Karin M.

“…Treatment of locally advanced rectal cancer includes chemoradiation and surgery, but patient response to treatment is variable. Patients who have a complete…”
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Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma by Saha, Supriya K, Gordan, John D, Kleinstiver, Benjamin P, Vu, Phuong, Najem, Mortada S, Yeo, Jia-Chi, Shi, Lei, Kato, Yasutaka, Levin, Rebecca S, Webber, James T, Damon, Leah J, Egan, Regina K, Greninger, Patricia, McDermott, Ultan, Garnett, Mathew J, Jenkins, Roger L, Rieger-Christ, Kimberly M, Sullivan, Travis B, Hezel, Aram F, Liss, Andrew S, Mizukami, Yusuke, Goyal, Lipika, Ferrone, Cristina R, Zhu, Andrew X, Joung, J Keith, Shokat, Kevan M, Benes, Cyril H, Bardeesy, Nabeel

“…Intrahepatic cholangiocarcinoma (ICC) is an aggressive liver bile duct malignancy exhibiting frequent isocitrate dehydrogenase (IDH1/IDH2) mutations. Through a…”
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Differential Effector Engagement by Oncogenic KRAS by Yuan, Tina L., Amzallag, Arnaud, Bagni, Rachel, Yi, Ming, Afghani, Shervin, Burgan, William, Fer, Nicole, Strathern, Leslie A., Powell, Katie, Smith, Brian, Waters, Andrew M., Drubin, David, Thomson, Ty, Liao, Rosy, Greninger, Patricia, Stein, Giovanna T., Murchie, Ellen, Cortez, Eliane, Egan, Regina K., Procter, Lauren, Bess, Matthew, Cheng, Kwong Tai, Lee, Chih-Shia, Lee, Liam Changwoo, Fellmann, Christof, Stephens, Robert, Luo, Ji, Lowe, Scott W., Benes, Cyril H., McCormick, Frank

“…KRAS can bind numerous effector proteins, which activate different downstream signaling events. The best known are RAF, phosphatidylinositide (PI)-3′ kinase,…”
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The prevalence of childhood asthma: interpreting falling rates in the context of shifting measurement and the COVID-19 pandemic by Frey, Sean M., Rowe, Regina K., Halterman, Jill S.

“…The estimated prevalence of childhood asthma in the United States, as measured by the National Health Information Survey (NHIS), has decreased by 30% since…”
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Mechanistic biomarkers for clinical decision making in rheumatic diseases by Robinson, William H., Lindstrom, Tamsin M., Cheung, Regina K., Sokolove, Jeremy

“…Biomarkers have the potential to improve all aspects of clinical practice, from diagnosis to monitoring of treatment effectiveness. In this Review, the authors…”
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Author Correction: Sarcopenia risk and associated factors among Chinese community-dwelling older adults living alone by Cheng, Li, Sit, Janet W. H., Chan, Helen Y. L., Choi, Kai Chow, Cheung, Regina K. Y., Wong, Martin M. H., Li, Francis Y. K., Lee, Tin Yan, Fung, Elina S. M., Tai, Keen Man, So, Winnie K. W.

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Survival of Adult Female Bighorn Sheep Following a Pneumonia Epizootic by DEKELAITA, DANIELLA J., EPPS, CLINTON W., STEWART, KELLEY M., SEDINGER, JAMES S., POWERS, JENNY G., GONZALES, BEN J., ABELLA-VU, REGINA K., DARBY, NEAL W., HUGHSON, DEBRA L.

“…Beginning in the early 1900s, poly-factorial, poly-microbial pneumonia was identified as a disease affecting bighorn sheep (Ovis canadensis) and it continues…”
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