Search Results - "Rege, Sushil D."
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Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs
Published in Analytical biochemistry (15-12-2010)“…Dot-blot is a versatile and simple analysis to perform. We adapted this method as a simple identity test for monoclonal antibodies to a number of small…”
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An Efficient Synthesis of a Heterobifunctional Coupling Agent
Published in Bioconjugate chemistry (01-09-2005)“…An efficient synthesis of…”
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Investigations into self-association of vancomycin covalent dimers using surface plasmon resonance technology
Published in Bioorganic & medicinal chemistry letters (16-08-1999)“…Covalent dimers of vancomycin linked through the vancosamine sugar moieties of the glycopeptide antibiotic have been synthesized in one step in 67–69% yield…”
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Studies on Intramolecular Higher-Order Cycloaddition Reactions
Published in Journal of organic chemistry (09-02-1996)“…Thermal, metal-free, and metal-promoted intramolecular higher-order cycloadditions are described. Substrates in which the tropone (2,4,6-cycloheptatrien-1-one)…”
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Structure-Binding Relationships for the Interaction between a Vancomycin Monoclonal Antibody Fab Fragment and a Library of Vancomycin Analogues and Tracers
Published in Bioconjugate chemistry (01-03-1999)“…A series of vancomycin analogues and tracers were synthesized, and their binding interactions with an anti-vancomycin Fab fragment were evaluated under mass…”
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Binding interactions of vancomycin tracers with a bacterial cell wall peptidoglycan analogue
Published in Bioorganic & medicinal chemistry letters (17-07-2000)“…Binding interactions between several vancomycin tracers and ( N, N′-diacetyl)K dA dA in solution were evaluated in a competition format using a surface plasmon…”
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Synthesis of labeled galactosylhydroxylysine
Published in Journal of labelled compounds & radiopharmaceuticals (15-03-2001)“…A concise synthesis of isotopically labeled galactosylhydroxylysine (2) was achieved via glycosylation of labeled hydroxylysine derivative (3) with…”
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Stereoselective Synthesis of Ferrocenylamino Acids
Published in Synthetic communications (01-04-2000)“…Enantiopure ferrocenyl-β, and bis-β-amino acids [(R)-(+)-1 and (R, R)-(+)-2] were prepared from (S)-(+)-sulfinimine (3) and (S, S)-(+)-bis-sulfinimine (4)…”
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Synthesis of Galactosylhydroxylysine and its Analogs
Published in Synthetic communications (01-09-2000)“…Synthesis of (--)-galactosylhydroxylysine (GHL, I), and its analogs (+)-2 and (+)-3, which are essential for development of assays for osteoporosis, is…”
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Synthesis of isotopically labeled (+)-deoxypyridinoline
Published in Journal of labelled compounds & radiopharmaceuticals (01-04-2000)“…An efficient synthesis of isotopically labeled (+)‐deoxypyridinoline (3) was achieved via quaternization of (S,S)(−)‐4 with (S)‐(−)‐iodide (5) and subsequent…”
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Development of a quantitative vancomycin immunoassay for the abbott AxSYM analyzer
Published in Therapeutic drug monitoring (01-04-1998)“…A novel fluorescence polarization immunoassay for vancomycin on Abbott AxSYM analyzer is described. The immunoassay allows for the accurate quantification of…”
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