Search Results - "Regan, Daniel"

Canine sarcomas as a surrogate for the human disease by Gustafson, Daniel L., Duval, Dawn L., Regan, Daniel P., Thamm, Douglas H.

“…Pet dogs are becoming increasingly recognized as a population with the potential to inform medical research through their treatment for a variety of maladies…”
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Mesenchymal Stem Cells (MSC) Derived from Induced Pluripotent Stem Cells (iPSC) Equivalent to Adipose‐Derived MSC in Promoting Intestinal Healing and Microbiome Normalization in Mouse Inflammatory Bowel Disease Model by Soontararak, Sirikul, Chow, Lyndah, Johnson, Valerie, Coy, Jonathan, Wheat, William, Regan, Daniel, Dow, Steven

“…Cellular therapy with allogeneic or autologous mesenchymal stem cells (MSC) has emerged as a promising new therapeutic strategy for managing inflammatory bowel…”
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Bony ingrowth potential of 3D-printed porous titanium alloy: a direct comparison of interbody cage materials in an in vivo ovine lumbar fusion model by McGilvray, Kirk C., Easley, Jeremiah, Seim, Howard B., Regan, Daniel, Berven, Sigurd H., Hsu, Wellington K., Mroz, Thomas E., Puttlitz, Christian M.

“…There is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that three-dimensional (3D)-printed…”
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The Angiotensin Receptor Blocker Losartan Suppresses Growth of Pulmonary Metastases via AT1R-Independent Inhibition of CCR2 Signaling and Monocyte Recruitment by Regan, Daniel P, Coy, Jonathan W, Chahal, Kirti Kandhwal, Chow, Lyndah, Kurihara, Jade N, Guth, Amanda M, Kufareva, Irina, Dow, Steven W

“…Inflammatory monocytes have been shown to play key roles in cancer metastasis through promotion of tumor cell extravasation, growth, and angiogenesis. Monocyte…”
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Integrated analysis of canine soft tissue sarcomas identifies recurrent mutations in TP53, KMT genes and PDGFB fusions by Das, Sunetra, Idate, Rupa, Lana, Susan E., Regan, Daniel P., Duval, Dawn L.

“…Soft tissue sarcomas (STS) are a heterogenous group of mesenchymal tumors representing over 50 distinct types with overlapping histological features and…”
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Author Correction: Integrated analysis of canine soft tissue sarcomas identifies recurrent mutations in TP53, KMT genes and PDGFB fusions by Das, Sunetra, Idate, Rupa, Lana, Susan E., Regan, Daniel P., Duval, Dawn L.

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Losartan Blocks Osteosarcoma-Elicited Monocyte Recruitment, and Combined With the Kinase Inhibitor Toceranib, Exerts Significant Clinical Benefit in Canine Metastatic Osteosarcoma by Regan, Daniel P, Chow, Lyndah, Das, Sunetra, Haines, Laurel, Palmer, Eric, Kurihara, Jade N, Coy, Jonathan W, Mathias, Alissa, Thamm, Douglas H, Gustafson, Daniel L, Dow, Steven W

“…There is increasing recognition that progress in immuno-oncology could be accelerated by evaluating immune-based therapies in dogs with spontaneous cancers…”
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Cancer immunotherapy in veterinary medicine: Current options and new developments by Regan, Daniel, Guth, Amanda, Coy, Jonathan, Dow, Steven

“…•Developments in tumor immunotherapy are advancing rapidly.•Autologous tumor vaccines are showing significant promise.•Antibody targeted therapeutics will soon…”
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Mesenchymal Stem Cells Recruit CCR2 + Monocytes To Suppress Allergic Airway Inflammation by Takeda, Katsuyuki, Webb, Tracy L, Ning, Fangkun, Shiraishi, Yoshiki, Regan, Daniel P, Chow, Lyndah, Smith, Mia J, Ashino, Shigeru, Guth, Amanda M, Hopkins, Sophie, Gelfand, Erwin W, Dow, Steven

“…Mesenchymal stem cells (MSC) exert immune modulatory properties and previous studies demonstrated suppressive effects of MSC treatment in animal models of…”
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NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer by Schmahl, Michelle J, Regan, Daniel P, Rivers, Adam C, Joesten, William C, Kennedy, Michael A

“…Pancreatic cancer is the third leading cause of cancer deaths in the United States with more than 53,000 expected to be diagnosed with the disease in 2018. The…”
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Molecular landscape of canine soft tissue sarcoma by Das, Sunetra, Idate, Rupa, Regan, Daniel P., Lana, Susan E., Duval, Dawn L.

“…Canine soft tissue sarcomas (STS) are a heterogenous group of malignant tumors arising from mesenchymal cells of soft tissues. This simplified collective of…”
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Transcriptional regulation of alcohol induced liver fibrosis in a translational porcine hepatocellular carcinoma model by Yasmin, Alvi, Regan, Daniel P., Schook, Lawrence B., Gaba, Ron C., Schachtschneider, Kyle M.

“…Hepatocellular carcinoma (HCC) is the 5th most common and 2nd deadliest cancer worldwide. HCC risk factors include alcohol induced liver cirrhosis, which…”
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Effects of recent cannabis consumption on eye-tracking and pupillometry by Haider, Mohammad N, Regan, Daniel, Hoque, Mahamudul, Ali, Fahed, Ilowitz, Andrew

“…Cannabis consumption is known to immediately affect ocular and oculomotor function, however, cannabis consumption is also known to affect it for a prolonged…”
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Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease by Barnard, Rebecca A, Regan, Daniel P, Hansen, Ryan J, Maycotte, Paola, Thorburn, Andrew, Gustafson, Daniel L

“…The autophagy pathway has been recognized as a mechanism of survival and therapy resistance in cancer, yet the extent of autophagy's function in metastatic…”
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Improved Recovery of Captured Airborne Bacteria and Viruses with Liquid-Coated Air Filters by Regan, Daniel P., Fong, ChunKi, Bond, Avery C. S., Desjardins, Claudia, Hardcastle, Justin, Hung, Shao-Hsiang, Holmes, Andrew P., Schiffman, Jessica D., Maginnis, Melissa S., Howell, Caitlin

“…The COVID-19 pandemic has revealed the importance of the detection of airborne pathogens. Here, we present composite air filters featuring a bioinspired liquid…”
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Investigation of Gastrointestinal Toxicities Associated with Concurrent Abdominal Radiation Therapy and the Tyrosine Kinase Inhibitor Sunitinib in a Mouse Model by Prebble, Amber R, Latka, Bailey, Burdekin, Braden, Leary, Del, Harris, Mac, Regan, Daniel, Boss, Mary-Keara

“…Tyrosine kinase inhibitors (TKIs) may be combined with radiation therapy (RT) to enhance tumor control; however, increased incidences of gastrointestinal (GI)…”
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Canine oral squamous cell carcinoma as a spontaneous, translational model for radiation and immunology research by Boss, Mary-Keara, Harrison, Lauren G, Gold, Alexandra, Karam, Sana D, Regan, Daniel P

“…Improving outcomes for oral squamous cell carcinoma (OSCC) patients has been hindered by a lack of effective predictive animal models. Spontaneously occurring…”
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Antimicrobial efficacy of cyclic α- and β-peptides incorporated in polyurethane coatings by Lu, Qin, Regan, Daniel P, Barlow, Daniel E, Fears, Kenan P

“…Microbial growth on surfaces poses health concerns and can accelerate the biodegradation of engineered materials and coatings. Cyclic peptides are promising…”
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Biphasic Interpositional Allograft for Rotator Cuff Repair Augmentation Is Safe in an Ovine Model by Credille, Kevin T, Wang, Zachary R C, Horner, Nolan S, Regan, Daniel P, Gadomski, Benjamin C, Easley, Jeremiah T, Garrigues, Grant E, Yanke, Adam B

“…To perform a preclinical histologic assessment of a biphasic acellular interpositional cancellous allograft in an ovine model of rotator cuff repair (RCR)…”
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Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis by Zhou, Hengbo, Blevins, Melanie A, Hsu, Jessica Y, Kong, Deguang, Galbraith, Matthew D, Goodspeed, Andrew, Culp-Hill, Rachel, Oliphant, Michael U J, Ramirez, Dominique, Zhang, Lingdi, Trinidad-Pineiro, Jennyvette, Mathews Griner, Lesley, King, Rebecca, Barnaeva, Elena, Hu, Xin, Southall, Noel T, Ferrer, Marc, Gustafson, Daniel L, Regan, Daniel P, D'Alessandro, Angelo, Costello, James C, Patnaik, Samarjit, Marugan, Juan, Zhao, Rui, Ford, Heide L

“…Metastasis is the major cause of mortality for patients with cancer, and dysregulation of developmental signaling pathways can significantly contribute to the…”
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