Search Results - "Regal, JF"

Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus by Teske, Sabine, Bohn, Andrea A, Regal, Jean F, Neumiller, Joshua J, Lawrence, B Paige

“…Unlike their role in bacterial infection, less is known about the role of neutrophils during pulmonary viral infection. Exposure to pollutant…”
Get more information

Arginase Activity Differs with Allergen in the Effector Phase of Ovalbumin- versus Trimellitic Anhydride-Induced Asthma by Greene, Amy L., Rutherford, Mark S., Regal, Ronald R., Flickinger, Gail H., Hendrickson, Julie A., Giulivi, Cecilia, Mohrman, Margaret E., Fraser, Daniel G., Regal, Jean F.

“…Both trimellitic anhydride (TMA), a small molecular weight chemical, and ovalbumin (OVA), a reference protein allergen, cause asthma with eosinophilia. To test…”
Get full text

Trimellitic anhydride (TMA) dust induces airway obstruction and eosinophilia in non-sensitized guinea pigs by Larsen, Christen P, Regal, Jean F

“…Trimellitic anhydride (TMA) causes asthma after a latency period of sensitization. In non-sensitized humans and animals, limited studies indicate that TMA…”
Get full text

Trimellitic anhydride-induced allergic response in the guinea pig lung involves antibody-dependent and -independent complement system activation by Larsen, C P, Regal, R R, Regal, J F

“…Trimellitic anhydride (TMA) is one of many low molecular weight compounds known to cause occupational asthma. In our previous studies the TMA-induced allergic…”
Get more information

Trimellitic Anhydride-Induced Eosinophilia in a Mouse Model of Occupational Asthma by Regal, Jean F., Mohrman, Margaret E., Sailstad, Denise M.

“…Trimellitic anhydride (TMA) is a low-molecular-weight chemical known to cause occupational asthma. The present study was designed to determine if TMA elicited…”
Get full text

Trimellitic anhydride-induced cellular infiltration into Guinea pig lung varies with age but not gender by Larsen, Christen P, Regal, Jean F

“…In humans the incidence of asthma changes with age and gender. Immature guinea pigs have been used to model the allergic response to the occupational allergen…”
Get more information

Role of the complement system in pulmonary disorders by Regal, Jean F.

“…Immune injury in the lung is classically divided into types I-IV hypersensitivity, with the complement system being involved in types II and III…”
Get full text

OZONE DIFFERENTIALLY MODULATES AIRWAY RESPONSIVENESS IN ATOPIC VERSUS NONATOPIC GUINEA PIGS by Schlesinger, Richard B., Cohen, Mitchell D., Gordon, Terry, Nadziejko, Christine, Zelikoff, Judith T., Sisco, Maureen, Regal, Jean F., Ménache, Margaret G.

“…While acute exposures to ozone (O 3) can alter airway responsiveness, effects from long-term exposures at low concentrations are less clear. This study…”
Get full text

The Role of IgG1 and IgG2 in Trimellitic Anhydride-Induced Allergic Response in the Guinea Pig Lung by Fraser, Daniel G., Graziano, Frank M., Larsen, Christen P., Regal, Jean F.

“…Trimellitic anhydride (TMA) is a small molecular weight chemical used in the paint and plastics industry that can cause asthma-like symptoms in humans. Guinea…”
Get full text

Trimellitic anhydride-induced allergic response in the lung: role of the complement system in cellular changes by Fraser, D G, Regal, J F, Arndt, M L

“…Trimellitic anhydride (TMA) is a small molecular weight industrial compound that will cause asthma-like symptoms in humans. Some of these TMA-induced symptoms…”
Get more information

Minor role of the C3a receptor in systemic anaphylaxis in the guinea pig by Regal, Jean F, Klos, Andreas

“…Previously, Regal et al. [Regal, J.F., Fraser, D.G., Toth, C.A., 1993. Role of the complement system in antigen-induced bronchoconstriction and changes in…”
Get full text

Systemic complement system depletion does not inhibit cellular accumulation in antihistamine pretreated allergic guinea pig lung by Regal, J F, Fraser, D G

“…The present study was designed to determine if depletion of the complement system in the circulation with cobra venom factor (CVF) prevented the cellular…”
Get more information

Role of the complement system in antigen-induced bronchoconstriction and changes in blood pressure in the guinea pig by Regal, J F, Fraser, D G, Toth, C A

“…Systemic anaphylaxis involves life-threatening bronchoconstriction and a serious hypotensive response often complicated by cardiac arrhythmias. The purpose of…”
Get more information

Role of arachidonate metabolites in C5a-induced bronchoconstriction by Regal, J F

“…The complement cleavage product, C5a, causes a bronchoconstriction in the guinea pig as evidenced by a decrease in dynamic lung compliance and an increase in…”
Get more information

Enhancement of antigen-induced bronchoconstriction in the guinea pig after intravascular complement activation with cobra venom factor by Regal, J F

“…The purpose of the present studies was to begin to test the hypothesis that the complement system is important for antigen-induced bronchoconstriction in the…”
Get more information

Enhancement of antigen-induced bronchoconstriction after intravascular complement activation with cobra venom factor. Reversal by granulocyte depletion by Regal, JF, Fraser, DG, Anderson, DE, Solem, LE

“…Our previous studies have demonstrated that activation of the C system with cobra venom factor (CVF) in a passively sensitized guinea pig results in an…”
Get full text

Role of circulating white blood cells in the enhancement of antigen-induced bronchoconstriction after intravascular complement activation with cobra venom factor by Regal, J F, Fraser, D G

Get more information

Reduced anaphylactic responsiveness of strain 2 guinea pigs by Heller, L J, Regal, J F

“…Strain 2 guinea pigs have been shown to have diminished anaphylactic responsiveness. In the present study, experiments were conducted comparing various…”
Get more information

C5a-induced bronchoconstriction: absence of a role of circulating white blood cells and platelets by Regal, J F

“…C5a causes an intense bronchoconstriction when injected intravenously into the guinea pig. The present study was designed to determine if circulating white…”
Get more information

C5a-induced tracheal contraction: effect of an SRS-A antagonist and inhibitors of arachidonate metabolism by Regal, JF, Pickering, RJ

“…C5a, a peptide derived from the fifth component of complement, has been shown to cause significant prolonged smooth muscle contraction in isolated guinea pig…”
Get full text