Search Results - "Refsnes, M"

Particulate matter properties and health effects: consistency of epidemiological and toxicological studies by Schwarze, P E, Ovrevik, J, Låg, M, Refsnes, M, Nafstad, P, Hetland, R B, Dybing, E

“…Identifying the ambient particulate matter (PM) fractions or constituents, critically involved in eliciting adverse health effects, is crucial to the…”
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Role of size and surface area for pro-inflammatory responses to silica nanoparticles in epithelial lung cells: Importance of exposure conditions by Skuland, T., Øvrevik, J., Låg, M., Refsnes, M.

“…•Si500 were equally or more potent than Si50 at equal surface area concentrations.•The relative cytokine responses were influenced by exposure conditions.•The…”
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Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution by Øvrevik, J, Låg, M, Holme, J.A, Schwarze, P.E, Refsnes, M

“…Abstract Airborne particulate matter (PM) has a complex composition, and the relative contribution of different compounds to PM-induced effects is only partly…”
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Inflammation-Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro by Holme, Jørn A., Magne, Refsnes, Låg, M., Totlandsdal, A. I., Schwarze, Per, Øvrevik, J.

“…Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in humans. In the development of these effects inflammation is regarded as a…”
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Hyphae fragments from A. fumigatus sensitize lung cells to silica particles (Min-U-Sil): Increased release of IL-1β by Øya, E., Zegeye, F.D., Bølling, A.K., Øvstebø, R., Afanou, A.K.J., Øvrevik, J., Refsnes, M., Holme, J.A.

“…Exposure to particulate matter (PM), such as mineral particles and biological particles/components may be linked to aggravation of respiratory diseases,…”
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Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions by Hetland, R.B, Cassee, F.R, Refsnes, M, Schwarze, P.E, Låg, M, Boere, A.J.F, Dybing, E

“…Several studies have shown that particles of smaller size may be more potent than larger to induce inflammatory and toxic responses in cultured lung cells…”
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Enniatin B-induced cell death and inflammatory responses in RAW 267.4 murine macrophages by Gammelsrud, A., Solhaug, A., Dendelé, B., Sandberg, W.J., Ivanova, L., Kocbach Bølling, A., Lagadic-Gossmann, D., Refsnes, M., Becher, R., Eriksen, G., Holme, J.A.

“…The mycotoxin enniatin B (EnnB) is predominantly produced by species of the Fusarium genera, and often found in grain. The cytotoxic effect of EnnB has been…”
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Air pollution-related metals induce differential cytokine responses in bronchial epithelial cells by Låg, M, Øvrevik, J, Totlandsdal, A I, Lilleaas, E M, Thormodsæter, A, Holme, J A, Schwarze, P E, Refsnes, M

“…Different transition metals have been shown to induce inflammatory responses in lung. We have compared eight different metal ions with regard to cytokine…”
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TACE/TGF-α/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components by ØVREVIK, J, REFSNES, M, TOTLANDSDAL, A. I, HOLME, J. A, SCHWARZE, P. E, LAG, M

“…Airborne particulate matter (PM) may induce or exacerbate neutrophilic airway disease by triggering the release of inflammatory mediators, such as CXC…”
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Differential binding of cytokines to environmentally relevant particles: A possible source for misinterpretation of in vitro results? by Kocbach, A., Totlandsdal, A.I., Låg, M., Refsnes, M., Schwarze, P.E.

“…Inflammation is considered as a key event in adverse health effects associated with exposure to ambient particulate matter. The inflammatory potential of…”
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Importance of Size and Composition of Particles for Effects on Cells In Vitro by Schwarze, P. E., Øvrevik, J., Hetland, R. B., Becher, R., Cassee, F. R., Låg, M., Løvik, M., Dybing, E., Refsnes, M.

“…A primary goal of current research on particle-induced health effects is to reveal the critical characteristics that determine their biological effects…”
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Fluoride-induced apoptosis in epithelial lung cells involves activation of MAP kinases p38 and possibly JNK by THRANE, E. V, REFSNES, M, THORESEN, G. H, LAG, M, SCHWARZE, P. E

“…Exposure to fluorides can induce inflammatory reactions, cell cycle arrest, and apoptosis in different experimental systems. Fluorides are known G-protein…”
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Fluoride-induced apoptosis in human epithelial lung cells (A549 cells): role of different G protein-linked signal systems by Refsnes, Magne, Schwarze, Per E, Holme, Jørn A, Låg, Marit

“…In the present study, possible mechanisms involved in fluoride-induced apoptosis in a human epithelial lung cell line (A549) were examined. Sodium fluoride…”
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Zinc- and Copper-Induced Interleukin-6 Release in Primary Cell Cultures From Rat Heart by Ansteinsson, V., Refsnes, M., Skomedal, T., Osnes, J. B., Schiander, I., Låg, M.

“…The metals, zinc (Zn 2+ ) and copper (Cu 2+ ) from inhaled particulate matter may reach the systemic circulation and the cardiac tissue. In the present study,…”
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Cadmium-induced apoptosis of primary epithelial lung cells: Involvement of Bax and p53, but not of oxidative stress by LAG, M, WESTLY, S, LERSTAD, T, BJØRNSRUD, C, REFSNES, M, SCHWARZE, P. E

“…The lung is a target organ for cadmium (Cd) toxicity. Apoptosis induced by cadmium acetate (CdAc) was studied in alveolar type 2 cells and Clara cells isolated…”
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RAT LUNG INFLAMMATORY RESPONSES AFTER IN VIVO AND IN VITRO EXPOSURE TO VARIOUS STONE PARTICLES by Becher, Rune, Hetland, Ragna B., Refsnes, Magne, Dahl, Jon E., Dahlman, Hans Jørgen, Schwarze, Per E.

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Involvement of Protein Kinase C in Fluoride-Induced Apoptosis in Different Types of Lung Cells by REFSNES, M., KERSTEN, H., SCHWARZE, P. E., LÅG, M.

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Importance of soluble metals and reactive oxygen species for cytokine release induced by mineral particles by Hetland, R.B, Myhre, O, Låg, M, Hongve, D, Schwarze, P.E, Refsnes, M

“…The mechanisms for particle-induced health effects are not well understood, but inflammation seems to be of importance. Previously, we have shown that stone…”
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Mechanisms involved in the induction of apoptosis by T-2 and HT-2 toxins in HL-60 human promyelocytic leukemia cells by HOLME, J. A, MORRISON, E, SAMUELSEN, J. T, WIGER, R, LAG, M, SCHWARZE, P. E, BERNHOFT, A, REFSNES, M

“…T-2 and HT-2 toxins belong to a group of mycotoxins that are widely encountered as natural contaminants known to elicit toxic responses in hematopoietic cells…”
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Effect of silver nanoparticles on mitogen-activated protein kinases activation: role of reactive oxygen species and implication in DNA damage by Rinna, Alessandra, Magdolenova, Zuzana, Hudecova, Alexandra, Kruszewski, Marcin, Refsnes, Magne, Dusinska, Maria

“…Large quantities of engineered nanoparticles (NP), such as nanosilver (AgNP), have been widely applied, leading to an increased exposure and potential health…”
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