Search Results - "Refolo, Maria Grazia"
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Inflammatory Mechanisms of HCC Development
Published in Cancers (10-03-2020)“…HCC (hepatocellular carcinoma) is the second leading cause of cancer deaths worldwide, with several etiologic causes, mostly inflammation-associated. Different…”
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Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines
Published in Journal of cellular physiology (01-12-2015)“…Quercetin, the major constituent of flavonoid and widely present in fruits and vegetables, is an attractive compound for cancer prevention due to its…”
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Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro
Published in BMC cancer (27-01-2014)“…Thrombocytopenia has been reported to be associated with small size HCCs, and thrombocytosis to be associated with large size HCCs. The aim was to examine the…”
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4
Nonalcoholic Fatty Liver Disease: Focus on New Biomarkers and Lifestyle Interventions
Published in International journal of molecular sciences (09-04-2021)“…Nonalcoholic fatty liver disease (NAFLD) is considered a hepatic manifestation of metabolic syndrome, characterized from pathological changes in lipid and…”
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Stearoyl-CoA Desaturase-1 Enzyme Inhibition by Grape Skin Extracts Affects Membrane Fluidity in Human Colon Cancer Cell Lines
Published in Nutrients (04-03-2020)“…The polyphenolic compounds present in grape extracts have chemopreventive and anticancer properties. Here, we studied the ability of two grape skin extracts…”
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6
The role of miRNA-133b and its target gene SIRT1 in FAP-derived desmoid tumor
Published in Oncotarget (30-06-2020)“…Signaling pathways have a key role in driving the uncontrolled development of familial adenomatous polyposis (FAP)- associated and sporadic desmoid tumors…”
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Corrigendum: Variations in circulating levels of angiopoietin-2 over time are predictive of ramucirumab-paclitaxel therapy outcome in advanced gastric cancer: results of prospective study
Published in Frontiers in oncology (14-04-2023)“…[This corrects the article DOI: 10.3389/fonc.2022.862116.]…”
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Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab-Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study
Published in Frontiers in oncology (06-04-2022)“…The combination of paclitaxel and ramucirumab is the second-line therapy of choice in the treatment of advanced gastric cancer. To date, no biomarkers are…”
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The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines
Published in Frontiers in oncology (16-02-2023)“…Paclitaxel (PTX) interferes with microtubule architecture by binding to β-tubulin, thereby blocking progression at the G2/M phase and inducing apoptosis. This…”
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10
Quercetin Inhibits Human DLD-1 Colon Cancer Cell Growth and Polyamine Biosynthesis
Published in Anticancer research (01-09-2010)“…Polyamines and ornithine decarboxylase are involved in cell growth and differentiation. The polyphenol quercetin may exert anti-tumour properties by…”
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Modulation of Regorafenib effects on HCC cell lines by epidermal growth factor
Published in Cancer chemotherapy and pharmacology (01-06-2015)“…Purpose Blood platelet numbers are correlated to growth and aggressiveness of several tumor types, including hepatocellular carcinoma (HCC). We previously…”
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VEGFA Status as a Predictive Marker of Therapy Outcome in Metastatic Gastric Cancer Patients Following Ramucirumab-Based Treatment
Published in Biomedicines (07-10-2023)“…Metastatic gastric cancer (mGC) often has a poor prognosis and may benefit from a few targeted therapies. Ramucirumab-based anti-angiogenic therapy targeting…”
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13
Modulation of Doxorubicin mediated growth inhibition of hepatocellular carcinoma cells by platelet lysates
Published in Anti-cancer agents in medicinal chemistry (01-01-2014)“…Platelet extracts can stimulate cell growth and contribute to tumor biology. It was recently shown that they stimulate the growth of hepatocellular carcinoma…”
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Integrated immune gene expression signature and molecular classification in gastric cancer: New insights
Published in Journal of leukocyte biology (01-08-2020)“…Gastric cancer (GC) is characterized by extreme heterogeneity due to histopathological differences, molecular characteristics, and immune gene expression…”
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Chlorogenic Acid Improves the Regorafenib Effects in Human Hepatocellular Carcinoma Cells
Published in International journal of molecular sciences (19-05-2018)“…Chlorogenic acid (CGA) is a polyphenol present in many human dietary foods. Several studies indicated a beneficial role of CGA in the prevention of cancer and…”
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Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines
Published in Scientific reports (28-04-2020)“…Ramucirumab is approved both as monotherapy and in combination with Paclitaxel for advanced gastric cancer in patients with disease progression after…”
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IGF-1R tyrosine kinase inhibitors and Vitamin K1 enhance the antitumor effects of Regorafenib in HCC cell lines
Published in Oncotarget (28-11-2017)“…The recent RESORCE trial showed that treatment with Regorafenib after Sorafenib failure provided a significant improvement in overall survival in HCC patients…”
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Abstract 259: Modulation of doxorubicin actions on HCC cells by insulin-like growth factor-I
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Tumor microenvironment is increasingly understood to influence tumor biology in many tumor types, including HCC. We recently showed that platelets…”
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Cannabinoid Receptor-1 Up-regulation in Azoxymethane (AOM)-treated Mice After Dietary Treatment with Quercetin
Published in Anticancer research (01-08-2018)“…The expression of cannabinoid receptor-1 (CB1-R) seems to be modulated by bioactive natural components such as the flavonoid quercetin. The aim of this study…”
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Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: Growth inhibition, quiescence, and recovery
Published in Journal of cellular physiology (01-02-2013)“…To evaluate the growth‐inhibitory properties of the potent multi‐kinase antagonist Regorafenib (Fluoro‐Sorafenib), which was synthesized as a more potent…”
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