Search Results - "Refika Yigit"

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study by Eerkens, Anneke L., Brummel, Koen, Vledder, Annegé, Paijens, Sterre T., Requesens, Marta, Loiero, Dominik, van Rooij, Nienke, Plat, Annechien, Haan, Floris-Jan, Klok, Patty, Yigit, Refika, Roelofsen, Thijs, de Lange, Natascha M., Klomp, Rie, Church, David, ter Elst, Arja, Wardenaar, René, Spierings, Diana, Foijer, Floris, Koelzer, Viktor Hendrik, Bosse, Tjalling, Bart, Joost, Jalving, Mathilde, Reyners, Anna K. L., de Bruyn, Marco, Nijman, Hans W.

“…Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in…”
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The risk of lymph node metastasis in the new FIGO 2018 stage IA cervical cancer with >7 mm diameter by Nicolai, Laure, Yigit, Refika, Bleeker, Maaike C G, Bart, Joost, van der Velden, Jacobus, Mom, Constantijne H

“…In the 2018 FIGO staging system, cervical cancers with ≤5 mm depth of invasion (DOI) and a diameter of >7 mm, first classified as stage IB, are classified as…”
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Survival of Ovarian Cancer Patients Is Independent of the Presence of DC and T Cell Subsets in Ascites by Wefers, Christina, Duiveman-de Boer, Tjitske, Yigit, Refika, Zusterzeel, Petra L M, van Altena, Anne M, Massuger, Leon F A G, De Vries, I Jolanda M

“…Ascites is a prominent feature of ovarian cancer and could serve as liquid biopsy to assess the immune status of patients. Tumor-infiltrating T lymphocytes are…”
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The risk of lymph node metastasis in the new FIGO 2018 stage IA cervical cancer with >7 mm diameter by Laure Nicolai, Refika Yigit, Maaike C. G. Bleeker, Joost Bart, Jacobus Van Der Velden, Constantijne H. Mom

“…Objective: In the 2018 FIGO staging system, cervical cancers with ≤5 mm depth of invasion (DOI) and a diameter of >7 mm, first classified as stage IB, are…”
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First-in-Human Phase I Clinical Trial of an SFV-Based RNA Replicon Cancer Vaccine against HPV-Induced Cancers by Komdeur, Fenne L., Singh, Amrita, van de Wall, Stephanie, Meulenberg, Janneke J.M., Boerma, Annemarie, Hoogeboom, Baukje Nynke, Paijens, Sterre T., Oyarce, Cesar, de Bruyn, Marco, Schuuring, Ed, Regts, Joke, Marra, Ruben, Werner, Naomi, Sluis, Jessica, van der Zee, Ate G.J., Wilschut, Jan C., Allersma, Derk P., van Zanten, Coba J., Kosterink, Jos G.W., Jorritsma-Smit, Annelies, Yigit, Refika, Nijman, Hans W., Daemen, Toos

“…A first-in-human phase I trial of Vvax001, an alphavirus-based therapeutic cancer vaccine against human papillomavirus (HPV)-induced cancers was performed…”
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Survival of patients with early-stage cervical cancer after abdominal or laparoscopic radical hysterectomy: a nationwide cohort study and literature review by Wenzel, Hans H.B., Smolders, Ramon G.V., Beltman, Jogchum J., Lambrechts, Sandrina, Trum, Hans W., Yigit, Refika, Zusterzeel, Petra L.M., Zweemer, Ronald P., Mom, Constantijne H., Bekkers, Ruud L.M., Lemmens, Valery E.P.P., Nijman, Hans W., Van der Aa, Maaike A.

“…Recently, the safety of laparoscopic radical hysterectomy (LRH) has been called into question in early-stage cervical cancer. This study aimed to evaluate…”
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Chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning in breast cancer patients by Deprez, Sabine, Amant, Frederic, Yigit, Refika, Porke, Kathleen, Verhoeven, Judith, Stock, Jan Van den, Smeets, Ann, Christiaens, Marie-Rose, Leemans, Alexander, Hecke, Wim Van, Vandenberghe, Joris, Vandenbulcke, Mathieu, Sunaert, Stefan

“…A subgroup of patients with breast cancer suffers from mild cognitive impairment after chemotherapy. To uncover the neural substrate of these mental…”
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CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma by Workel, Hagma H, Komdeur, Fenne L, Wouters, Maartje C.A, Plat, Annechien, Klip, Harry G, Eggink, Florine A, Wisman, G. Bea A, Arts, Henriette J.G, Oonk, Maaike H.M, Mourits, Marian J.E, Yigit, Refika, Versluis, Marco, Duiker, Evelien W, Hollema, Harry, de Bruyn, Marco, Nijman, Hans W

“…Abstract Introduction Intraepithelial CD8+ tumour-infiltrating T-lymphocytes (TIL) are associated with a prolonged survival in endometrial cancer (EC). By…”
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Ovarian cancer creates a suppressive microenvironment to escape immune elimination by Yigit, Refika, Massuger, Leon F.A.G, Figdor, Carl G, Torensma, Ruurd

“…Abstract Background Considering the high mortality rate of ovarian cancer due to the absence of curative treatment in advanced stage or at recurrence, new…”
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B cells critical for outcome in high grade serous ovarian carcinoma by Vledder, Annegé, Paijens, Sterre T., Loiero, Dominik, Maagdenberg, Alexis, Duiker, Evelien W., Bart, Joost, Hendriks, Anne M., Jalving, Mathilde, Werner, Naomi, Rooij, Nienke, Plat, Annechien, Wisman, G. Bea A., Yigit, Refika, Roelofsen, Thijs, Kruse, Arnold J., Lange, Nastascha M., Koelzer, Viktor H., Bruyn, Marco, Nijman, Hans W.

“…Recent work has shown evidence for the prognostic significance of tumor infiltrating B cells (B‐TIL) in high grade serous ovarian carcinoma (HGSOC), the…”
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Abstract 4044: Draining lymph nodes in ovarian cancer patients have a naïve immune cell signature by Brunekreeft, Kim, Komdeur, Fenne, Workel, Hagma, Eggink, Florine, Plat, Annechien, Yigit, Refika, Hollema, Harry, Duiker, Evelien, Nijman, Hans, Bruyn, Marco

“…Abstract Purpose: Ovarian cancer (OC) is characterized by an immunosuppressive tumor micro-environment (TME). We speculated that the effects of this…”
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Impact of hormonal biomarkers on response to hormonal therapy in advanced and recurrent endometrial cancer by van Weelden, Willem Jan, Lalisang, Roy I., Bulten, Johan, Lindemann, Kristina, van Beekhuizen, Heleen J., Trum, Hans, Boll, Dorry, Werner, Henrica M.J., van Lonkhuijzen, Luc R.C.W., Yigit, Refika, Forsse, David, Witteveen, Petronella O., Galaal, Khadra, van Ginkel, Alexandra, Bignotti, Eliana, Weinberger, Vit, Sweegers, Sanne, Kroep, Judith R., Cabrera, Silvia, Snijders, Marc P.L.M., Inda, Márcia A., Eriksson, Ane Gerda Z., Krakstad, Camilla, Romano, Andrea, van de Stolpe, Anja, Pijnenborg, Johanna M.A.

“…Approximately 20% of women with endometrial cancer have advanced-stage disease or suffer from a recurrence. For these women, prognosis is poor, and palliative…”
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Optimising follow-up strategy based on cytology and human papillomavirus after fertility-sparing surgery for early stage cervical cancer: a nationwide, population-based, retrospective cohort study by Schuurman, Teska N, Schaafsma, Mirte, To, Kaylee H, Verhoef, Viola M J, Sikorska, Karolina, Siebers, Albert G, Wenzel, Hans H B, Bleeker, Maaike C G, Roes, Eva Maria, Zweemer, Ronald P, de Vos van Steenwijk, Peggy J, Yigit, Refika, Beltman, Jogchum J, Zusterzeel, Petra L M, Lok, Christianne A R, Bekkers, Ruud L M, Mom, Constantijne H, van Trommel, Nienke E

“…The optimal follow-up strategy to detect recurrence after fertility-sparing surgery for early stage cervical cancer is unknown. Tailored surveillance based on…”
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Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer by Wouters, Maartje C A, Komdeur, Fenne L, Workel, Hagma H, Klip, Harry G, Plat, Annechien, Kooi, Neeltje M, Wisman, G Bea A, Mourits, Marian J E, Arts, Henriette J G, Oonk, Maaike H M, Yigit, Refika, de Jong, Steven, Melief, Cornelis J M, Hollema, Harry, Duiker, Evelien W, Daemen, Toos, de Bruyn, Marco, Nijman, Hans W

“…Tumor-infiltrating lymphocytes (TIL) are associated with a better prognosis in high-grade serous ovarian cancer (HGSC). However, it is largely unknown how this…”
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Evaluation of the recently established Dutch nationwide Archipelago of Ovarian Cancer Research biobank by Zelisse, Hein S., van Gent, Mignon D.J.M., Mom, Constantijne H., de Ridder, Sander, Snijders, Malou L.H., Heeling, Marlou, Stoter, Matthijs, Broeks, Annegien, Horlings, Hugo M., Lok, Christianne A.R., Bosch, Steven L., Piek, Jurgen M., Bart, Joost, Reyners, Anna K.L., Wisman, G. Bea A., Yigit, Refika, Boere, Ingrid A., Collée, Margriet, Groenendijk, Floris H., Jansen, Maurice P.H.M., Roes, Eva-Maria, Hofhuis, Ward, Hoogduin, Klaas J., Alcalá, Luthy S.M., Smedts, Huberdina P.M., Makkus, Alexander C.F., Nieuwenhuyzen-de Boer, Gatske M., van Es, Nicole, Vencken, Peggy M.L.H., van Altena, Anne M., Simons, Michiel, Hazelbag, Hans Marten, Kagie, Marjolein J., Aliredjo, Riena, Bonestroo, Tijmen J.J., Bosse, Tjalling, de Kroon, Cor D., Brinkhuis, Mariël, Janssen, Marc-Jan, Koster, Nils C., Kruse, Arnold-Jan, Gerestein, Cornelis G., Jonges, Trudy G.N., Zweemer, Ronald P., Kooreman, Loes F.S., Lambrechts, Sandrina, Ebisch, Inge M.W., de Kievit van der Heijden, Ineke M., Voorham, Quirinus J., van der Aa, Maaike A., Belien, Jeroen A.M., van de Vijver, Marc J., Dijk, Frederike

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Hormone Receptor Expression and Activity for Different Tumour Locations in Patients with Advanced and Recurrent Endometrial Carcinoma by Luijten, Maartje M W, van Weelden, Willem Jan, Lalisang, Roy I, Bulten, Johan, Lindemann, Kristina, van Beekhuizen, Heleen J, Trum, Hans, Boll, Dorry, Werner, Henrica M J, van Lonkhuijzen, Luc R C W, Yigit, Refika, Krakstad, Camilla, Witteveen, Petronella O, Galaal, Khadra, van Ginkel, Alexandra A, Bignotti, Eliana, Weinberger, Vit, Sweegers, Sanne, Eriksson, Ane Gerda Z, Keizer, Diederick M, van de Stolpe, Anja, Romano, Andrea, Pijnenborg, Johanna M A, European Network For Individualized Treatment In Endometrial Cancer

“…Response to hormonal therapy in advanced and recurrent endometrial cancer (EC) can be predicted by oestrogen and progesterone receptor immunohistochemical…”
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Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research by Zelisse, Hein S, van Gent, Mignon D J M, de Ridder, Sander, van der Aa, Maaike A, van Altena, Anne M, Bart, Joost, Belien, Jeroen A M, Boere, Ingrid A, Bosch, Steven L, Broeks, Annegien, Bulten, Johan, Collée, Margriet, Groenendijk, Floris H, Horlings, Hugo M, Jansen, Maurice P H M, Jonges, Trudy G N, Kooreman, Loes F S, de Kroon, Cornelis D, Lambrechts, Sandrina, Lok, Christianne A R, Piek, Jurgen M, Reyners, Anna K L, Roes, Eva-Maria, Simons, Michiel, Wisman, G Bea A, Yigit, Refika, Zweemer, Ronald P, Mom, Constantijne H, van de Vijver, Marc J, Dijk, Frederike

“…Ovarian cancer has the worst overall survival rate of all gynecologic malignancies. For the majority of patients, the 5-year overall survival rate of less than…”
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Cytokine analysis as a tool to understand tumour–host interaction in ovarian cancer by Yigit, Refika, Figdor, Carl G, Zusterzeel, Petra L.M, Pots, Jeanette M, Torensma, Ruurd, Massuger, Leon F.A.G

“…Abstract Epithelial ovarian cancer (EOC) is an immunogenic tumour and exploits many suppressive ways to escape immune eradication. EOC is known to spread…”
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Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study by Eerkens, Anneke L., Brummel, Koen, Vledder, Annegé, Paijens, Sterre T., Requesens, Marta, Loiero, Dominik, van Rooij, Nienke, Plat, Annechien, Haan, Floris-Jan, Klok, Patty, Yigit, Refika, Roelofsen, Thijs, de Lange, Natascha M., Klomp, Rie, Church, David, ter Elst, Arja, Wardenaar, René, Spierings, Diana, Foijer, Floris, Koelzer, Viktor Hendrik, Bosse, Tjalling, Bart, Joost, Jalving, Mathilde, Reyners, Anna K. L., de Bruyn, Marco, Nijman, Hans W.

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Cytokine profiles in cyst fluids from ovarian tumors reflect immunosuppressive state of the tumor by Yigit, Refika, Massuger, Leon F A G, Zusterzeel, Petra L M, Pots, Jeanette, Figdor, Carl G, Torensma, Ruurd

“…Ovarian tumors, both benign and malignant, often contain cystic lesions. Analysis of cytokine levels of this enclosed fluid may be a pure way to study cytokine…”
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