Search Results - "Reeves, Raymond"

High mobility group (HMG) proteins: Modulators of chromatin structure and DNA repair in mammalian cells by Reeves, Raymond

“…•Members of the HMGN family seem to be mainly involved in ‘decompacting’ or loosening up chromatin structure to allow access of repair enzymes and complexes to…”
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Molecular biology of HMGA proteins: hubs of nuclear function by Reeves, Raymond

“…Members of the HMGA (a.k.a. HMGI/Y) family of ‘high mobility group’ (HMG) proteins participate in a wide variety of nuclear processes ranging from chromosome…”
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Trichomonosis, a common curable STI, and prostate carcinogenesis--a proposed molecular mechanism by Sutcliffe, Siobhan, Neace, Calvin, Magnuson, Nancy S, Reeves, Raymond, Alderete, J F

“…[...]as further epidemiologic evidence for an association between trichomonosis and prostate cancer risk, African Americans, who have the highest incidence of…”
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Why target PIM1 for cancer diagnosis and treatment? by Magnuson, Nancy S, Wang, Zeping, Ding, Gang, Reeves, Raymond

“…The highly conserved proto-oncogenic protein PIM1 is an unusual serine or threonine kinase, in part because it is constitutively active. Overexpression of PIM1…”
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Metabolomics of colorectal cancer: past and current analytical platforms by Williams, Michael D., Reeves, Raymond, Resar, Linda S., Hill, Herbert H.

“…Metabolomics is coming of age as an important area of investigation which may help reveal answers to questions left unanswered or only partially understood…”
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Network of Dynamic Interactions between Histone H1 and High-Mobility-Group Proteins in Chromatin by Catez, Frédéric, Yang, Huan, Tracey, Kevin J., Reeves, Raymond, Misteli, Tom, Bustin, Michael

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HMGA1 Drives Metabolic Reprogramming of Intestinal Epithelium during Hyperproliferation, Polyposis, and Colorectal Carcinogenesis by Williams, Michael D, Zhang, Xing, Belton, Amy S, Xian, Lingling, Huso, Tait, Park, Jeong-Jin, Siems, William F, Gang, David R, Resar, Linda M. S, Reeves, Raymond, Hill, Herbert H

“…Although significant progress has been made in the diagnosis and treatment of colorectal cancer (CRC), it remains a leading cause of cancer death worldwide…”
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Role of high mobility group (HMG) chromatin proteins in DNA repair by Reeves, Raymond, Adair, Jennifer E.

“…While the structure and composition of chromatin not only influences the type and extent of DNA damage incurred by eukaryotic cells, it also poses a major…”
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Nuclear functions of the HMG proteins by Reeves, Raymond

“…Although the three families of mammalian HMG proteins (HMGA, HMGB and HMGN) participate in many of the same nuclear processes, each family plays its own unique…”
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Architectural Transcription Factor HMGI(Y) Promotes Tumor Progression and Mesenchymal Transition of Human Epithelial Cells by Reeves, Raymond, Edberg, Dale D., Li, Ying

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HMGA proteins: flexibility finds a nuclear niche? by Reeves, Raymond

“…The mammalian HMGA family of chromatin proteins possesses an unusual constellation of physical, biochemical, and biological characteristics that distinguish…”
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HMGA1 Levels Influence Mitochondrial Function and Mitochondrial DNA Repair Efficiency by Mao, Li, Wertzler, Kelsey J., Maloney, Scott C., Wang, Zeping, Magnuson, Nancy S., Reeves, Raymond

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Recruitment of SWI/SNF to the Human Immunodeficiency Virus Type 1 Promoter by Henderson, Angus, Holloway, Adele, Reeves, Raymond, Tremethick, David John

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Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia by Baron, Rebecca M, Lopez-Guzman, Silvia, Riascos, Dario F, Macias, Alvaro A, Layne, Matthew D, Cheng, Guiying, Harris, Cailin, Chung, Su Wol, Reeves, Raymond, von Andrian, Ulrich H, Perrella, Mark A

“…The architectural transcription factor High Mobility Group-A1 (HMGA1) binds to the minor groove of AT-rich DNA and forms transcription factor complexes…”
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Inhibition of Nucleotide Excision Repair by High Mobility Group Protein HMGA1 by Adair, Jennifer E., Kwon, YoungHo, Dement, Gregory A., Smerdon, Michael J., Reeves, Raymond

“…The mammalian non-histone “high mobility group” A (HMGA) proteins are the primary nuclear proteins that bind to the minor groove of AT-rich DNA. They may,…”
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HMGA1a: sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA by Manabe, Takayuki, Ohe, Kenji, Katayama, Taiichi, Matsuzaki, Shinsuke, Yanagita, Takeshi, Okuda, Hiroaki, Bando, Yoshio, Imaizumi, Kazunori, Reeves, Raymond, Tohyama, Masaya, Mayeda, Akila

“…Aberrant exon 5 skipping of presenilin-2 (PS2) pre-mRNA produces a deleterious protein isoform PS2V, which is almost exclusively observed in the brains of…”
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Dynamic mitochondrial localization of nuclear transcription factor HMGA1 by Dement, Gregory A., Treff, Nathan R., Magnuson, Nancy S., Franceschi, Vincent, Reeves, Raymond

“…It has been well established that high mobility group A1 (HMGA1) proteins act within the nucleus of mammalian cells as architectural transcription factors that…”
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NMR resonance assignments of the human high mobility group protein HMGA1 by Buchko, Garry W, Ni, Shuisong, Lourette, Natacha M, Reeves, Raymond, Kennedy, Michael A

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Dynamic and Differential in Vivo Modifications of the Isoform HMGA1a and HMGA1b Chromatin Proteins by Edberg, Dale D., Adkins, Joshua N., Springer, David L., Reeves, Raymond

“…Most naturally occurring mammalian cancers and immortalized tissue culture cell lines share a common characteristic, the overexpression of full-length HMGA1…”
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A Scalable Asymmetric Synthesis of (R)-2-Amino-1-(3-pyridinyl)ethanol Dihydrochloride via an Oxazaborolidine Catalyzed Borane Reduction by Duquette, Jason, Zhang, Mingbao, Zhu, Lei, Reeves, Raymond S

“…This report describes a scalable process for the asymmetric synthesis of (R)-2-amino-1-(3-pyridinyl)ethanol dihydrochloride. The stereochemistry of the product…”
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